Detailed information NTG0438810

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: HGO93_RS00460
• Genome accession: NZ_CP051482
• Coordinates: 82396..83439 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain NGA104a
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 77396..88439

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HGO93_RS00430 (HGO93_09910)	-	77762..77873 (+)	112	Protein_85	hypothetical protein	-
HGO93_RS00435 (HGO93_09905)	-	77902..78315 (+)	414	WP_001837236.1	hypothetical protein	-
HGO93_RS00440 (HGO93_09900)	-	78805..79791 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
HGO93_RS00445 (HGO93_09895)	map	80322..81080 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
HGO93_RS00450 (HGO93_09890)	-	81297..81683 (+)	387	WP_001110179.1	hypothetical protein	-
HGO93_RS00455 (HGO93_09885)	liaF	81698..82399 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
HGO93_RS00460 (HGO93_09880)	vraS	82396..83439 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
HGO93_RS00465 (HGO93_09875)	vraR	83429..84058 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
HGO93_RS00470 (HGO93_09870)	-	84170..85381 (-)	1212	WP_000037091.1	YihY/virulence factor BrkB family protein	-
HGO93_RS00475 (HGO93_09865)	-	85659..85934 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
HGO93_RS00480 (HGO93_09860)	-	85941..86405 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
HGO93_RS00485 (HGO93_09855)	-	86552..86752 (+)	201	WP_078153768.1	DUF1128 family protein	-
HGO93_RS00490 (HGO93_09850)	-	86755..88011 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=438810 HGO93_RS00460 WP_001017131.1 82396..83439(+) (vraS) [Staphylococcus aureus strain NGA104a]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=438810 HGO93_RS00460 WP_001017131.1 82396..83439(+) (vraS) [Staphylococcus aureus strain NGA104a]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1