Detailed information NTG0438800

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HF085_RS10535
• Genome accession: NZ_CP051479
• Coordinates: 2145085..2145972 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NGA76
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2140085..2150972

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HF085_RS10505 (HF085_13480)	-	2140817..2141578 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
HF085_RS10510 (HF085_13475)	-	2141823..2142278 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HF085_RS10515	-	2142400..2142501 (+)	102	WP_000731972.1	SE2200 family small protein	-
HF085_RS10520 (HF085_13465)	-	2142561..2143985 (-)	1425	WP_000953744.1	alkaline phosphatase	-
HF085_RS10525 (HF085_13460)	-	2144183..2144383 (+)	201	WP_000604727.1	hypothetical protein	-
HF085_RS10530 (HF085_13455)	braR	2144409..2145074 (+)	666	WP_000697887.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HF085_RS10535 (HF085_13450)	braS	2145085..2145972 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HF085_RS10540 (HF085_13445)	-	2146080..2146835 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HF085_RS10545 (HF085_13440)	-	2146832..2148832 (+)	2001	WP_000776733.1	ABC transporter permease	-
HF085_RS10550 (HF085_13435)	-	2149491..2149604 (+)	114	WP_011447078.1	hypothetical protein	-
HF085_RS10555 (HF085_13430)	-	2149986..2150246 (+)	261	WP_001789307.1	hypothetical protein	-
HF085_RS10560 (HF085_13425)	-	2150256..2150753 (+)	498	WP_001065268.1	glutathione peroxidase	-
HF085_RS10565 (HF085_13420)	-	2150861..2150944 (-)	84	WP_031797553.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=438800 HF085_RS10535 WP_000143419.1 2145085..2145972(+) (braS) [Staphylococcus aureus strain NGA76]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=438800 HF085_RS10535 WP_000143419.1 2145085..2145972(+) (braS) [Staphylococcus aureus strain NGA76]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997