Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   IOO21_RS06000 Genome accession   NZ_CP063357
Coordinates   1162323..1164125 (-) Length   600 a.a.
NCBI ID   WP_002869075.1    Uniprot ID   A1W0N0
Organism   Campylobacter jejuni strain R4B202     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1157323..1169125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IOO21_RS05975 - 1157452..1158651 (+) 1200 WP_002856604.1 MFS transporter -
  IOO21_RS05980 ciaC 1158707..1159027 (+) 321 WP_002866237.1 invasion antigen CiaC -
  IOO21_RS05985 hemE 1159207..1160229 (+) 1023 WP_002856507.1 uroporphyrinogen decarboxylase -
  IOO21_RS05990 - 1160226..1161128 (+) 903 WP_002869073.1 radical SAM protein -
  IOO21_RS05995 - 1161125..1162321 (-) 1197 WP_002869074.1 hypothetical protein -
  IOO21_RS06000 uvrC 1162323..1164125 (-) 1803 WP_002869075.1 excinuclease ABC subunit UvrC Machinery gene
  IOO21_RS06005 - 1164118..1164612 (-) 495 WP_002869076.1 hypothetical protein -
  IOO21_RS06010 guaA 1164751..1166286 (+) 1536 WP_002869077.1 glutamine-hydrolyzing GMP synthase -
  IOO21_RS06015 - 1166372..1167832 (+) 1461 WP_002869078.1 hypothetical protein -

Sequence

Protein


Download         Length: 600 a.a.        Molecular weight: 69788.90 Da        Isoelectric Point: 9.4998

>NTDB_id=438076 IOO21_RS06000 WP_002869075.1 1162323..1164125(-) (uvrC) [Campylobacter jejuni strain R4B202]
MTKENLENELKTLPNSAGVYQYFNQEGKLLYVGKAKNLKNRVKSYFAFTPNLHANPRNSLRIQKMIEETVHLEFITTNSE
ADALILENSFIKQLHPKYNILLRDDKTYPYIYVNFEEEFPRFEITRKLVKKSKIKYFGPFFKGARELLDALYLYYPLKQK
ASCKSPCIFYQISRCLAPCDKRISKEKYLEILDEAMHALLNPSILIKNLEKQMLVLAQNENYEEAAKVRDQIVTIKDLEV
KVEMDVAKLEDFEVFALAFEDSMLSTLRFVVQNGKIISANSKITPIKNDIQWDQNEIYKQLILENFSMDIPLLANVIYVY
EEFEDRVLLEEILSQRFDKKISIKIPKIGEKRRICDLAFQNALLNIEKEQKNHDFTIQKELKFYFELENLPNDIEIFDNS
HLQGVANVGAMVTYRINSWDKSKYRKFHLKHKNDYDQMREVLTRRALDFDKIPPPDLWLIDGGKVLLDLAKKIIVSSGAN
VDILAISKEKIDAKAHRAKGGAKDKIHSLKGEFSLSINDKKLQFLQKLRDEAHRFAISFHQNTKKKQDLKSSKLANLGLS
SGVIQKLLAYYGNFESIYKADFKDLTMLVGRKAAQKIKEN

Nucleotide


Download         Length: 1803 bp        

>NTDB_id=438076 IOO21_RS06000 WP_002869075.1 1162323..1164125(-) (uvrC) [Campylobacter jejuni strain R4B202]
TTGACTAAAGAGAATTTAGAAAATGAGCTAAAAACTCTTCCCAATAGTGCTGGAGTTTATCAATACTTTAATCAAGAAGG
AAAGCTTTTATATGTAGGTAAGGCTAAAAATCTTAAAAATCGTGTCAAATCTTATTTTGCTTTTACTCCAAATTTACATG
CAAATCCAAGAAATTCTTTAAGAATTCAAAAAATGATTGAAGAAACAGTGCATTTGGAATTTATCACTACTAATTCAGAA
GCCGATGCTTTGATTTTGGAAAATTCTTTTATCAAACAACTGCATCCAAAATATAATATTTTGCTAAGAGATGATAAAAC
TTATCCTTATATTTATGTCAATTTTGAAGAAGAATTTCCACGCTTTGAGATCACTAGAAAATTAGTAAAAAAAAGCAAAA
TTAAATATTTTGGCCCTTTTTTTAAAGGCGCTAGAGAGCTTTTAGATGCGCTTTATTTATACTATCCTTTAAAGCAAAAA
GCAAGTTGTAAATCCCCTTGTATTTTTTATCAAATTTCTCGTTGCCTTGCGCCTTGTGATAAACGCATCAGCAAAGAAAA
ATACCTTGAAATTTTAGATGAGGCTATGCACGCGCTTTTAAATCCTAGTATTTTAATAAAAAATTTAGAAAAACAAATGC
TTGTTTTAGCACAGAATGAAAATTATGAAGAAGCAGCTAAAGTAAGAGATCAGATTGTAACGATTAAGGATTTAGAAGTT
AAGGTTGAAATGGATGTTGCAAAATTAGAAGATTTTGAAGTGTTTGCTTTAGCTTTTGAAGATTCTATGCTTTCAACCTT
GCGTTTTGTAGTGCAAAATGGAAAAATTATCAGTGCAAATTCTAAAATTACTCCTATAAAAAATGATATACAATGGGATC
AAAATGAAATTTATAAGCAACTGATTTTAGAAAATTTTAGCATGGATATTCCTTTGCTTGCAAATGTTATTTATGTTTAT
GAAGAATTTGAAGATAGAGTGCTTTTAGAAGAAATTTTAAGCCAAAGGTTTGATAAAAAAATCAGTATTAAAATCCCTAA
AATAGGAGAAAAAAGAAGAATTTGTGATTTGGCTTTTCAAAATGCCCTTTTAAATATAGAAAAAGAGCAAAAAAATCATG
ATTTTACTATACAAAAAGAATTAAAGTTTTATTTTGAGCTTGAAAATTTACCAAATGATATAGAAATTTTTGACAATTCT
CATTTGCAAGGCGTGGCAAATGTTGGAGCTATGGTAACTTATAGAATAAATTCTTGGGATAAGTCAAAATATAGAAAATT
TCATTTAAAACATAAAAATGACTATGATCAAATGCGTGAAGTTTTAACGCGTAGGGCTTTGGACTTTGATAAAATACCTC
CTCCTGATTTATGGCTTATAGATGGGGGAAAGGTTTTGCTTGATTTGGCTAAAAAAATCATTGTAAGTAGTGGGGCAAAT
GTCGATATTTTAGCTATTTCAAAAGAAAAAATCGATGCAAAAGCACATAGAGCTAAAGGGGGTGCTAAGGATAAAATTCA
TTCCTTAAAAGGAGAATTTAGTCTAAGCATTAACGATAAAAAACTACAATTCTTACAGAAATTAAGAGATGAAGCACACC
GTTTTGCTATTAGCTTTCATCAAAATACTAAGAAAAAACAGGACTTGAAAAGTTCTAAGCTTGCAAATTTAGGACTTAGT
TCAGGGGTTATACAAAAACTTTTAGCGTATTATGGAAATTTTGAATCTATATATAAGGCTGATTTTAAAGATCTTACAAT
GCTTGTAGGCAGGAAAGCGGCGCAAAAGATAAAGGAAAATTGA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(205-236)

GIY-YIG catalytic domain (GIY-YIG)

(18-99)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-537)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A1W0N0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

46.907

97

0.455