Detailed information NTG0437323

Bioinformatically predicted

Overview

• Name: cytR
• Type: Regulator
• Locus tag: INR48_RS00280
• Genome accession: NZ_CP063153
• Coordinates: 46638..47663 (-)
• Length: 341 a.a.
• NCBI ID: WP_000644904.1
• Uniprot ID: P0ACN8
• Organism: Escherichia coli strain M7424
• Function: promote competence gene expression (predicted from homology) Competence regulation

Genomic Context

Location: 41638..52663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
INR48_RS00255 (INR48_00255)	rraA	42052..42537 (-)	486	WP_000872908.1	ribonuclease E activity regulator RraA	-
INR48_RS00260 (INR48_00260)	menA	42630..43556 (-)	927	WP_000139496.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
INR48_RS00265 (INR48_00265)	hslU	43623..44954 (-)	1332	WP_001293344.1	HslU--HslV peptidase ATPase subunit	-
INR48_RS00270 (INR48_00270)	hslV	44964..45494 (-)	531	WP_000208242.1	ATP-dependent protease subunit HslV	-
INR48_RS00275 (INR48_00275)	ftsN	45587..46546 (-)	960	WP_000068844.1	cell division protein FtsN	-
INR48_RS00280 (INR48_00280)	cytR	46638..47663 (-)	1026	WP_000644904.1	DNA-binding transcriptional regulator CytR	Regulator
INR48_RS00285 (INR48_00285)	priA	47819..50017 (-)	2199	WP_001309891.1	primosomal protein N'	Machinery gene
INR48_RS00290 (INR48_00290)	rpmE	50220..50432 (+)	213	WP_000710769.1	50S ribosomal protein L31	-
INR48_RS00295 (INR48_00295)	yiiX	50493..51101 (-)	609	WP_000702318.1	YiiX family permuted papain-like enzyme	-
INR48_RS00300 (INR48_00300)	metJ	51161..51478 (-)	318	WP_000852812.1	met regulon transcriptional regulator MetJ	-

Sequence

Protein

• Length: 341 a.a.
• Molecular weight: 37819.78 Da
• Isoelectric Point: 6.3842

>NTDB_id=437323 INR48_RS00280 WP_000644904.1 46638..47663(-) (cytR) [Escherichia coli strain M7424]
MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRVEKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDP
FFSEIIRGIEVTAANHGYLVLIGDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVDPQYIARGDFTFEAGSKAMQQLL
DLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLSIIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHV
GSGSRLMDCELIIRGSTRALP

Nucleotide

• Length: 1026 bp

>NTDB_id=437323 INR48_RS00280 WP_000644904.1 46638..47663(-) (cytR) [Escherichia coli strain M7424]
GTGAAAGCGAAGAAGCAGGAAACTGCCGCGACCATGAAAGACGTTGCCCTCAAGGCAAAAGTCTCTACAGCGACTGTCTC
CCGAGCATTAATGAATCCCGATAAAGTCTCCCAGGCCACCCGTAATCGGGTTGAAAAAGCGGCCCGGGAAGTGGGTTATT
TACCGCAGCCTATGGGACGCAACGTCAAGCGTAATGAATCCCGCACCATTCTGGTGATTGTCCCGGATATCTGCGATCCC
TTCTTTAGCGAAATTATTCGCGGTATCGAAGTTACGGCGGCAAATCACGGATATCTGGTGCTGATTGGCGACTGTGCGCA
TCAAAATCAGCAGGAAAAAACCTTTATCGATTTGATCATCACCAAGCAAATTGATGGCATGTTGCTGCTGGGTTCAAGGC
TGCCGTTTGATGCCAGCATTGAGGAACAGCGTAATCTGCCGCCGATGGTGATGGCGAACGAATTTGCACCGGAACTGGAG
CTGCCTACCGTTCATATCGACAATCTGACCGCCGCATTTGATGCAGTAAATTATTTATATGAGCAAGGGCATAAACGGAT
TGGCTGTATAGCCGGTCCCGAAGAGATGCCGCTGTGTCACTACCGCCTGCAAGGCTACGTTCAGGCGCTGCGTCGCTGCG
GCATTATGGTTGATCCGCAATACATCGCCCGTGGCGACTTCACCTTCGAAGCCGGAAGCAAAGCAATGCAACAGCTGCTT
GATCTTCCACAACCGCCTACTGCTGTCTTCTGCCATAGCGATGTGATGGCGCTCGGCGCACTTTCGCAGGCAAAACGCCA
GGGGCTGAAAGTCCCGGAAGACCTTTCCATAATCGGTTTTGATAACATCGACCTGACGCAATTTTGTGATCCGCCGCTGA
CAACCATCGCGCAGCCGCGTTACGAAATCGGTCGGGAAGCTATGCTGTTATTGCTTGATCAAATGCAGGGGCAACACGTT
GGCAGTGGCTCTCGTTTAATGGACTGCGAACTTATCATCCGGGGATCAACACGCGCGTTACCTTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (11-56)

• Periplasmic binding protein-like domain (Peripla_BP_3) (176-337)

3D structure

• AlphaFold DB: P0ACN8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cytR	Vibrio parahaemolyticus RIMD 2210633	64.179	98.24	0.63
cytR	Vibrio cholerae C6706	65.443	95.894	0.628