Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HGI44_RS04205 Genome accession   NZ_CP051291
Coordinates   867753..869537 (+) Length   594 a.a.
NCBI ID   WP_202136054.1    Uniprot ID   -
Organism   Helicobacter pylori strain ASHA-002     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 862753..874537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HGI44_RS04175 (HGI44_04170) motB 863408..864175 (+) 768 WP_202136051.1 flagellar motor protein MotB -
  HGI44_RS04180 (HGI44_04175) - 864179..864628 (+) 450 WP_001031788.1 hypothetical protein -
  HGI44_RS04185 (HGI44_04180) - 864802..866463 (+) 1662 WP_202136052.1 ABC transporter permease/substrate-binding protein -
  HGI44_RS04190 (HGI44_04185) - 866467..867108 (+) 642 WP_202136053.1 ATP-binding cassette domain-containing protein -
  HGI44_RS04195 (HGI44_04190) - 867120..867299 (-) 180 WP_000468794.1 hypothetical protein -
  HGI44_RS04200 (HGI44_04195) - 867291..867752 (+) 462 WP_000437188.1 hypothetical protein -
  HGI44_RS04205 (HGI44_04200) uvrC 867753..869537 (+) 1785 WP_202136054.1 excinuclease ABC subunit UvrC Machinery gene
  HGI44_RS04210 (HGI44_04205) - 869548..870813 (+) 1266 WP_202136055.1 homoserine dehydrogenase -
  HGI44_RS04215 (HGI44_04210) - 870814..871158 (+) 345 WP_001211675.1 YraN family protein -
  HGI44_RS04220 (HGI44_04215) trxA 871247..871567 (+) 321 WP_000020204.1 thioredoxin -
  HGI44_RS04225 (HGI44_04220) trxB 871573..872508 (+) 936 WP_202135856.1 thioredoxin-disulfide reductase -
  HGI44_RS04230 (HGI44_04225) - 872675..873496 (+) 822 WP_202135855.1 glycosyltransferase family 25 protein -
  HGI44_RS04235 (HGI44_04230) - 873701..873949 (-) 249 WP_000790556.1 RNA-binding protein -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68798.10 Da        Isoelectric Point: 9.6531

>NTDB_id=437249 HGI44_RS04205 WP_202136054.1 867753..869537(+) (uvrC) [Helicobacter pylori strain ASHA-002]
MADLLSSLKNLSHSSGVYQYFDKNHQLLYIGKAKNLKKRIKSYFSVRNNEITPNYRTSLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCENKITKEEYLKIAKECLEMIENKDKLIKELELKMERLSNNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGKGNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLN
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEAQSLFKLECMPYRVEIFDT
SHHANSQCVGGMVVYENHEFQKNSYRRYHLKGSNEYTQMSELLTRRALDFAKEPPPNLWVIDGGRVQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTASDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRI

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=437249 HGI44_RS04205 WP_202136054.1 867753..869537(+) (uvrC) [Helicobacter pylori strain ASHA-002]
ATGGCTGATTTATTGTCCAGTTTGAAAAACCTTTCTCATAGCAGTGGCGTGTATCAATATTTTGACAAAAACCACCAATT
ACTCTATATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGCAATAATGAAATCACGCCCA
ATTATCGCACCAGCTTACGCATCCAAATGATGGTCAAACAGATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTAGAAAATTCTTTAATCAAGCAGCTCAAACCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAAGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGAATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAAACTCATCAAAGAGCTTGAATTAA
AAATGGAGCGCCTTTCTAATAACTTGCGTTTTGAAGAAGCCCTCATTTATAGGGATAGGATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTATGATTTGGATATTTTTGCTTTTTATGGCAAGGGTAATAAGGCGGT
GTTGGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCTCTTAATGGGTTTGACA
CTGATGAAGCAATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCAGAACAGATTTTATTGAAC
GCTTGCTCTAATGAAACGCTTAAAGAATTGCAAGAATTTATCTCTCACCAATACTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAGGAAAAAACCTCTA
ATGAGGATCTGATTTTAGAAGAAGCGCAATCGCTCTTTAAATTAGAGTGCATGCCTTATAGAGTGGAAATCTTTGACACA
AGCCACCATGCCAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAATCATGAATTTCAAAAAAACTCCTATCGGCG
CTACCATTTAAAAGGCTCTAATGAATACACTCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTATGGGTGATCGATGGAGGGAGGGTGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGAGGCGCTAAAGACATTAT
CCACACCGCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCATAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGTATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCTGTTTTAAAAAAACGAATTTAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(384-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.97

100

0.97