Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HF584_RS12355 Genome accession   NZ_CP051165
Coordinates   2569299..2570015 (-) Length   238 a.a.
NCBI ID   WP_249740032.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NGA84b     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2564299..2575015
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HF584_RS12335 (HF584_10250) - 2565383..2566333 (+) 951 WP_054189588.1 LacI family DNA-binding transcriptional regulator -
  HF584_RS12340 (HF584_10245) - 2566482..2567966 (+) 1485 WP_054189589.1 sucrose-6-phosphate hydrolase -
  HF584_RS12345 (HF584_10240) - 2567963..2568922 (+) 960 WP_054189590.1 carbohydrate kinase -
  HF584_RS12350 (HF584_13875) - 2569119..2569227 (-) 109 Protein_2426 hypothetical protein -
  HF584_RS12355 (HF584_10235) agrA 2569299..2570015 (-) 717 WP_249740032.1 LytTR family DNA-binding domain-containing protein Regulator
  HF584_RS12360 (HF584_10230) - 2570034..2571326 (-) 1293 WP_054189592.1 GHKL domain-containing protein -
  HF584_RS12365 (HF584_10225) - 2571351..2571491 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  HF584_RS12370 (HF584_10220) - 2571488..2572057 (-) 570 WP_054189593.1 accessory gene regulator AgrB -
  HF584_RS12375 (HF584_13880) hld 2572347..2572427 (+) 81 WP_000046022.1 delta-hemolysin -
  HF584_RS12380 (HF584_10210) - 2573023..2573808 (-) 786 WP_054189594.1 carbon-nitrogen family hydrolase -
  HF584_RS12385 (HF584_10205) - 2574129..2574755 (-) 627 WP_054189595.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27881.88 Da        Isoelectric Point: 6.1590

>NTDB_id=436468 HF584_RS12355 WP_249740032.1 2569299..2570015(-) (agrA) [Staphylococcus aureus strain NGA84b]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDNRFFRCHNSFVVNRNNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=436468 HF584_RS12355 WP_249740032.1 2569299..2570015(-) (agrA) [Staphylococcus aureus strain NGA84b]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACCGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACTTTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCCGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACTAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATAATCGCTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCAATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.16

100

0.992