Detailed information NTG0043619

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: HIB_RS05920
• Genome accession: NC_016809
• Coordinates: 1148717..1149838 (-)
• Length: 373 a.a.
• NCBI ID: WP_015701982.1
• Uniprot ID: -
• Organism: Haemophilus influenzae 10810
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1143717..1154838

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HIB_RS05890 (HIB_11180)	dusB	1144161..1145141 (+)	981	WP_015701977.1	tRNA dihydrouridine synthase DusB	-
HIB_RS05895 (HIB_11190)	fis	1145135..1145434 (+)	300	WP_005651583.1	DNA-binding transcriptional regulator Fis	-
HIB_RS05900 (HIB_11200)	smpB	1145529..1146014 (-)	486	WP_015701978.1	SsrA-binding protein SmpB	-
HIB_RS05905 (HIB_11210)	pfkA	1146253..1147218 (-)	966	WP_015701979.1	6-phosphofructokinase	-
HIB_RS05910 (HIB_11220)	-	1147314..1147895 (-)	582	WP_015701980.1	hypothetical protein	-
HIB_RS05915 (HIB_11230)	yaaA	1147888..1148664 (-)	777	WP_015701981.1	peroxide stress protein YaaA	-
HIB_RS05920 (HIB_11240)	dprA	1148717..1149838 (-)	1122	WP_015701982.1	DNA-processing protein DprA	Machinery gene
HIB_RS05925 (HIB_11260)	leuA	1150413..1151960 (+)	1548	WP_015701984.1	2-isopropylmalate synthase	-
HIB_RS05930 (HIB_11270)	leuB	1152044..1153120 (+)	1077	WP_015701985.1	3-isopropylmalate dehydrogenase	-
HIB_RS05935 (HIB_11280)	leuC	1153297..1154706 (+)	1410	WP_015701986.1	3-isopropylmalate dehydratase large subunit	-

Sequence

Protein

• Length: 373 a.a.
• Molecular weight: 41612.68 Da
• Isoelectric Point: 6.4124

>NTDB_id=43619 HIB_RS05920 WP_015701982.1 1148717..1149838(-) (dprA) [Haemophilus influenzae 10810]
MNDITYTLLRLMQVPKLGGAGIDKILSNITLNELLNYDDVAFRQMGWGAIQIRRWFKPEAKFIEPALVWSQKEGNHLVNY
FSPFYPFLLKQTASFPPLLFVKGNLTALSQRQMAMVGSRYCTTYGEYWAKHFATELSLAGFTITSGLALGIDGHCHQAVV
NIQGQTIAVLGSGLEQIYPSKHQRLSAQIIENNGALVSEFLPNQAPIAANFPRRNRIISGLSVGTLVVEATEKSGSLITA
RYALEQNREVFAVPGNIQNESSQGCHRLIKQGAMLVENAKDILETLYQHSIHSQTEIDFDQIAVPNYTPPPDPRRLVEAP
SHPKLYSRIGYTPVSIDDLAEEFNLSVDVLLVQLLDLELQDLIISENGLYKRV

Nucleotide

• Length: 1122 bp

>NTDB_id=43619 HIB_RS05920 WP_015701982.1 1148717..1149838(-) (dprA) [Haemophilus influenzae 10810]
ATGAATGACATTACCTACACATTACTCCGTTTAATGCAAGTGCCTAAACTTGGCGGCGCTGGCATTGATAAAATTTTGTC
CAATATTACCTTAAATGAATTACTTAATTATGATGATGTTGCTTTCCGACAAATGGGGTGGGGAGCCATTCAAATTCGCC
GTTGGTTCAAGCCTGAAGCAAAATTTATTGAGCCTGCACTTGTGTGGTCACAAAAAGAGGGAAATCATTTAGTGAATTAT
TTTTCCCCTTTTTATCCCTTTTTGTTGAAACAGACCGCAAGTTTTCCGCCACTATTATTTGTAAAAGGAAATTTAACCGC
ACTTTCACAACGCCAAATGGCAATGGTTGGAAGCCGTTATTGCACGACTTACGGAGAATATTGGGCAAAACATTTTGCGA
CAGAACTTTCATTAGCTGGCTTTACGATTACTAGTGGACTTGCATTAGGAATTGATGGACATTGCCATCAAGCTGTGGTC
AATATTCAAGGGCAAACTATTGCGGTTTTAGGCAGTGGATTAGAACAAATCTATCCCTCTAAACATCAAAGATTATCGGC
ACAAATCATCGAAAATAATGGCGCATTAGTCTCTGAATTCTTACCAAACCAAGCCCCCATTGCCGCTAATTTCCCACGTC
GTAATCGGATTATTAGCGGGCTTTCAGTCGGCACGCTTGTTGTTGAAGCCACAGAAAAAAGCGGCTCGCTTATTACTGCG
CGATATGCGTTGGAACAAAACCGAGAGGTTTTTGCTGTGCCGGGAAACATTCAAAATGAATCAAGTCAAGGTTGTCATCG
CCTAATTAAACAAGGTGCAATGTTAGTAGAAAATGCTAAAGATATTTTGGAAACCCTCTACCAACATTCTATCCATAGCC
AAACTGAAATTGATTTTGACCAGATCGCCGTGCCTAATTACACGCCTCCACCTGATCCTCGTCGATTAGTAGAAGCACCA
AGCCACCCGAAACTTTATTCGCGTATTGGTTACACGCCTGTGAGCATTGATGATTTAGCTGAAGAATTTAATTTAAGCGT
CGATGTTTTGCTTGTTCAGTTGCTCGATCTTGAGTTGCAAGATCTTATCATAAGTGAAAATGGCTTATATAAACGCGTTT
AG

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (311-366)

• DNA recombination-mediator protein A (DNA_processg_A) (71-277)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Haemophilus influenzae Rd KW20	99.464	100	0.995
dprA	Glaesserella parasuis strain SC1401	52.011	93.298	0.485
dprA	Vibrio campbellii strain DS40M4	43.351	100	0.437
dprA	Vibrio cholerae strain A1552	43.288	97.855	0.424
dprA	Legionella pneumophila strain ERS1305867	40.634	93.029	0.378