Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   HIB_RS02860 Genome accession   NC_016809
Coordinates   550876..552213 (-) Length   445 a.a.
NCBI ID   WP_015701646.1    Uniprot ID   -
Organism   Haemophilus influenzae 10810     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 545876..557213
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIB_RS02835 (HIB_05390) - 547606..547878 (-) 273 WP_005630954.1 HU family DNA-binding protein -
  HIB_RS02840 (HIB_05400) - 548018..548608 (-) 591 WP_015701643.1 YjaG family protein -
  HIB_RS02845 (HIB_05410) nudC 548644..549438 (-) 795 WP_015701644.1 NAD(+) diphosphatase -
  HIB_RS02850 (HIB_05420) nfuA 549505..550101 (-) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  HIB_RS02855 (HIB_05430) - 550177..550863 (-) 687 WP_015701645.1 ComF family protein -
  HIB_RS02860 (HIB_05440) comE 550876..552213 (-) 1338 WP_015701646.1 type IV pilus secretin PilQ family protein Machinery gene
  HIB_RS02865 (HIB_05450) comD 552223..552636 (-) 414 WP_015701647.1 pilus assembly protein PilP Machinery gene
  HIB_RS02870 (HIB_05460) comC 552633..553154 (-) 522 WP_015701648.1 competence protein ComC Machinery gene
  HIB_RS02875 (HIB_05470) comB 553151..553657 (-) 507 WP_011272049.1 competence protein ComB Machinery gene
  HIB_RS02880 (HIB_05480) comA 553658..554455 (-) 798 WP_005693722.1 competence protein A Machinery gene
  HIB_RS02885 (HIB_05490) - 554554..557148 (+) 2595 WP_015701649.1 penicillin-binding protein 1A -

Sequence

Protein


Download         Length: 445 a.a.        Molecular weight: 49207.47 Da        Isoelectric Point: 7.8816

>NTDB_id=43600 HIB_RS02860 WP_015701646.1 550876..552213(-) (comE) [Haemophilus influenzae 10810]
MKKYFLKCGYFLVCFCLPLIVFANPKTDNERFFIRLSQAPLAQTLEQLAFQHDVNLVMGERLEGNISLKLNNIDMPRLLK
IIAKSKHLTLNKDDGVYYLNGSQSGKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPDGSITFDDRSN
LLVIQDEPRSVQNIKKLIAEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNVN
FATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREAV
LGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGDI
PIIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1338 bp        

>NTDB_id=43600 HIB_RS02860 WP_015701646.1 550876..552213(-) (comE) [Haemophilus influenzae 10810]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTTTAGTGTGTTTTTGTTTGCCATTAATCGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTAGCTCAAACACTAGAGCAATTAGCTTTTCAACATGATG
TCAATTTAGTGATGGGTGAGAGGTTAGAAGGCAATATTTCTTTGAAATTAAACAATATTGATATGCCACGTTTGCTAAAA
ATAATCGCAAAAAGTAAGCATCTTACTTTGAATAAAGATGATGGAGTTTATTATTTAAACGGCAGCCAATCTGGCAAAGG
TCAAGTTGCAGGAAATCTTACGACAAATGAACCACACTTAGTGAGTCACACGGTAAAACTTCATTTTGCTAAAGCCTCTG
AATTAATGAAATCCTTAACAACAGGAAGTGGATCTTTGCTTTCTCCCGATGGGAGCATTACCTTTGATGATCGCAGTAAT
TTGCTGGTTATTCAGGATGAACCTCGTTCTGTGCAAAATATCAAAAAACTGATTGCTGAAATGGATAAGCCTATTGAACA
GATCGCTATTGAAGCGCGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTAATC
CAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTAAAT
TTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTTGCCAAAATTAATGGGCGATTGCTTGATTTAGAATT
GAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGAGCA
TTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCGGTG
CTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCCTGG
TTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAGCAAGAAATTAATACTCAGGTTTTTGCCAAAGATG
GGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGATATA
CCCATTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTGACGCCACATAT
TTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(269-429)

Bacterial type II/III secretion system short domain (Secretin_N)

(123-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae 86-028NP

98.652

100

0.987
  comE Haemophilus influenzae Rd KW20

97.528

100

0.975
  comE Glaesserella parasuis strain SC1401

52

95.506

0.497
  pilQ Vibrio campbellii strain DS40M4

42.959

94.157

0.404
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.99

92.584

0.389
  pilQ Vibrio cholerae strain A1552

41.99

92.584

0.389

Multiple sequence alignment