Detailed information NTG0435892

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: GRB95_RS02790
• Genome accession: NZ_CP051004
• Coordinates: 504087..506348 (-)
• Length: 753 a.a.
• NCBI ID: WP_000882546.1
• Uniprot ID: A0AAD3A2V3
• Organism: Streptococcus agalactiae 515
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 499087..511348

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GRB95_RS02770 (GRB95_02770)	-	499116..499886 (+)	771	WP_001131467.1	DivIVA domain-containing protein	-
GRB95_RS02775 (GRB95_02775)	ileS	500171..502963 (+)	2793	WP_000768156.1	isoleucine--tRNA ligase	-
GRB95_RS02780 (GRB95_02780)	-	503080..503382 (-)	303	WP_001237035.1	DUF1827 family protein	-
GRB95_RS02785 (GRB95_02785)	-	503446..503901 (-)	456	WP_000184290.1	NUDIX hydrolase	-
GRB95_RS02790 (GRB95_02790)	clpE	504087..506348 (-)	2262	WP_000882546.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GRB95_RS02795 (GRB95_02795)	-	506646..506876 (+)	231	WP_000443582.1	DUF1797 family protein	-
GRB95_RS02800 (GRB95_02800)	-	507017..507709 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
GRB95_RS02805 (GRB95_02805)	-	507702..508436 (+)	735	WP_000230128.1	amino acid ABC transporter ATP-binding protein	-
GRB95_RS02810 (GRB95_02810)	-	508723..510417 (+)	1695	WP_001106854.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83803.04 Da
• Isoelectric Point: 5.2771

>NTDB_id=435892 GRB95_RS02790 WP_000882546.1 504087..506348(-) (clpE) [Streptococcus agalactiae 515]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQSGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENLKAQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVVKIAKAIRRNRVGLGIP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESTKG

Nucleotide

• Length: 2262 bp

>NTDB_id=435892 GRB95_RS02790 WP_000882546.1 504087..506348(-) (clpE) [Streptococcus agalactiae 515]
ATGCTCTGTCAAAACTGCAAACTTAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAATCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGTGAACCCGGCGTAGGGAAAACTGCTGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCTACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGCATGCAACCTGTAAAAGTCG
ATGAGCCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGCGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAACAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AACATGTGATCGGCCAGGATGACGCTGTCGTTAAGATTGCAAAAGCTATTCGTCGTAATCGAGTTGGTCTTGGTATCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGACATGTCAGAGTACATGGAAAAGCATGCCGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAATTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCTGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GCGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGACAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCAAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAAGAAAGTACAAAAGGTTGA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

• AAA lid domain (AAA_lid_9) (297-394)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.676	100	0.858
clpE	Streptococcus pneumoniae Rx1	85.581	99.469	0.851
clpE	Streptococcus pneumoniae D39	85.581	99.469	0.851
clpE	Streptococcus pneumoniae R6	85.581	99.469	0.851
clpE	Streptococcus pneumoniae TIGR4	85.447	99.469	0.85
clpC	Lactococcus lactis subsp. cremoris KW2	74.867	99.867	0.748
clpC	Bacillus subtilis subsp. subtilis str. 168	51.327	90.04	0.462
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.528	83.267	0.396
clpC	Streptococcus pneumoniae Rx1	46.845	84.197	0.394
clpC	Streptococcus pneumoniae D39	46.845	84.197	0.394
clpC	Streptococcus pneumoniae TIGR4	46.688	84.197	0.393
clpC	Streptococcus mutans UA159	47.03	82.736	0.389
clpC	Streptococcus thermophilus LMD-9	46.276	83.798	0.388
clpC	Streptococcus thermophilus LMG 18311	45.959	83.798	0.385