Detailed information NTG0043538

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SMUGS5_RS06390
• Genome accession: NC_018089
• Coordinates: 1343264..1345846 (-)
• Length: 860 a.a.
• NCBI ID: WP_002270957.1
• Uniprot ID: -
• Organism: Streptococcus mutans GS-5
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1338264..1350846

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMUGS5_RS06370 (SMUGS5_06340)	-	1338289..1339542 (-)	1254	WP_002279611.1	dihydrolipoamide acetyltransferase family protein	-
SMUGS5_RS06375 (SMUGS5_06345)	-	1339555..1340586 (-)	1032	WP_002267205.1	alpha-ketoacid dehydrogenase subunit beta	-
SMUGS5_RS06380 (SMUGS5_06350)	-	1340599..1341672 (-)	1074	WP_002263117.1	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	-
SMUGS5_RS06385 (SMUGS5_06355)	lpdA	1341698..1343035 (-)	1338	WP_002264928.1	dihydrolipoyl dehydrogenase	-
SMUGS5_RS06390 (SMUGS5_06360)	clpC	1343264..1345846 (-)	2583	WP_002270957.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SMUGS5_RS06395 (SMUGS5_06365)	glmM	1346040..1347389 (-)	1350	WP_002267731.1	phosphoglucosamine mutase	-
SMUGS5_RS06400 (SMUGS5_06370)	-	1347440..1348396 (-)	957	WP_002265809.1	YbbR-like domain-containing protein	-
SMUGS5_RS06405 (SMUGS5_06375)	cdaA	1348389..1349243 (-)	855	WP_002263112.1	diadenylate cyclase CdaA	-
SMUGS5_RS06410 (SMUGS5_06380)	murT	1349352..1350695 (+)	1344	WP_002270956.1	lipid II isoglutaminyl synthase subunit MurT	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98068.62 Da
• Isoelectric Point: 6.4498

>NTDB_id=43538 SMUGS5_RS06390 WP_002270957.1 1343264..1345846(-) (clpC) [Streptococcus mutans GS-5]
MIDKMTQLVEDSLEEAKELAIAHRNYQLDIPHLWAVLVKPDQFAFQFYQSLEINTNQLIEIINKEIDKIPVLSSTEKSSY
ARLYSQRLKNLLDDAHREMIDLKDQVLTVEHLILALFNQQRNPITVFLLEQGLNKEKLYQKMHRIRKGKPAISSSQETIY
DALEKYAVNLNQRALDEPVNKIIGRQNEMNDIIRILSRKNKNNAVLVGHSGVGKTAIIEGFVQRLVKNQVPKNLRGKIIY
SLDIGALLAGTKYRGEFEERFKALLNDIIDSNGQIILFIDEIHSIVSAGRTEGSVDAASILKPLLARGKIRIIGSTTHAE
YRESIEYDRALERRFQRILVHEPDLDYTMEILKGLKPIYENFHGVRLEEDSLEAAASLSKRYISDRFLPDKALDLIDEAC
AAKRLASHAYPVQMTNLSQQLISEKIRLLRLTDSDTDDKFKLNSHLEQLEEQKSQLLANWQRERELLDQVQELRSHLTAL
EEQANLALENNQVADYVRLEDEEIKICHQKMTALEKERLDSQKIINVTVTREDIAAVVERLTGIKVQGVMENERDRLLHL
EELLHQKIVGQDQAVQKVSQAIIRSRAGIQNPKRPIGSFLFLGPTGVGKTALAKRLAEVLFGSELEMVRLDMSEYMEKHA
VARLVGPPPGYVGYEEGGQLTEAVRQRLYSIVLLDEIEKAHPDVFNTLLQVLDEGRLTDSKGRTIDFKNTILIMTSNIGS
TNILQSLQDSGCITSEVRHKVLDELNHSFRPEFLNRIDETVLFNALSEKDMTGVVKVMVSDLQARLLEQDVHLTLTESVY
TLLAKEGFDAAFGARPMQRTIMQKLENPLALHLIQNQKNKEKETFVTVSVKDKKLKFTFS

Nucleotide

• Length: 2583 bp

>NTDB_id=43538 SMUGS5_RS06390 WP_002270957.1 1343264..1345846(-) (clpC) [Streptococcus mutans GS-5]
ATGATCGATAAAATGACTCAGTTAGTTGAAGATTCTTTAGAAGAAGCAAAGGAATTGGCTATTGCTCATCGTAATTATCA
GCTGGACATTCCCCATTTATGGGCTGTCTTGGTAAAACCTGATCAATTTGCTTTTCAATTCTATCAATCTTTAGAAATAA
ATACCAATCAGCTGATTGAGATTATCAATAAAGAAATAGATAAAATCCCAGTCCTTTCAAGTACAGAAAAAAGCAGTTAT
GCACGTTTATACAGTCAGCGTTTAAAAAATTTATTGGATGACGCACATCGGGAAATGATTGATTTAAAGGATCAGGTGCT
GACTGTAGAACACTTGATCTTGGCACTTTTTAACCAACAACGCAATCCCATTACTGTTTTTTTGCTTGAACAGGGTCTAA
ACAAAGAAAAACTTTATCAAAAGATGCATAGGATTCGTAAAGGGAAACCTGCTATTTCTTCCAGTCAAGAAACTATTTAT
GATGCTTTAGAAAAGTATGCTGTCAACTTAAATCAGCGTGCTTTAGATGAACCTGTTAATAAAATTATTGGCCGTCAGAA
TGAAATGAATGATATTATTCGTATTTTATCGCGTAAGAATAAGAATAATGCCGTTTTGGTTGGTCATTCAGGTGTTGGAA
AAACAGCCATTATTGAAGGATTTGTTCAGCGGTTAGTTAAAAATCAAGTTCCGAAAAATTTGCGAGGTAAGATCATTTAC
AGTCTTGACATAGGAGCCTTGCTGGCAGGAACTAAATACCGCGGTGAATTTGAAGAACGTTTCAAAGCTCTTCTCAATGA
TATTATAGACTCAAACGGTCAGATTATTCTTTTCATAGATGAAATTCATTCTATTGTCAGTGCAGGACGGACAGAGGGTT
CTGTTGATGCGGCCAGTATTTTGAAGCCGCTTTTGGCTAGAGGAAAAATTAGAATTATTGGTTCCACTACCCATGCAGAA
TACCGTGAAAGTATTGAATACGATAGGGCGTTAGAAAGACGTTTTCAAAGGATCTTAGTTCATGAACCAGATCTTGATTA
TACCATGGAAATTCTTAAAGGTCTCAAGCCCATTTATGAAAATTTTCATGGTGTCAGACTTGAAGAAGATAGTTTGGAAG
CTGCCGCAAGCTTGTCCAAGCGTTATATTTCTGATCGCTTTTTGCCAGATAAGGCTCTGGATTTAATTGACGAAGCCTGT
GCTGCTAAGCGGCTTGCTTCTCATGCTTATCCCGTGCAAATGACCAATTTGTCTCAGCAACTTATTTCTGAGAAAATTCG
TTTATTGCGTTTGACCGATTCTGACACTGACGATAAGTTTAAATTAAACAGTCATCTTGAGCAATTAGAGGAGCAAAAAA
GCCAATTATTAGCAAATTGGCAAAGGGAAAGAGAGCTCCTAGATCAGGTACAAGAGCTTCGTTCACATTTAACGGCTTTA
GAAGAGCAGGCTAATCTTGCTCTTGAAAATAATCAAGTCGCAGATTATGTCCGTCTAGAAGATGAGGAAATAAAGATATG
TCATCAAAAGATGACAGCTTTAGAAAAGGAACGTTTAGACAGTCAGAAGATAATTAATGTTACTGTGACTAGAGAAGATA
TAGCAGCTGTTGTTGAACGCTTGACAGGCATCAAAGTACAGGGTGTTATGGAAAACGAGCGTGATCGTCTCTTGCACTTA
GAAGAATTATTGCACCAAAAAATTGTTGGTCAAGATCAAGCCGTACAAAAGGTATCTCAGGCCATCATTCGCTCTCGTGC
TGGCATTCAAAACCCTAAACGTCCAATTGGCTCCTTCCTCTTTTTGGGACCGACTGGTGTGGGGAAAACAGCGCTTGCTA
AACGTTTGGCGGAAGTTCTTTTTGGCAGTGAACTTGAGATGGTGCGTCTCGATATGTCTGAATATATGGAAAAACATGCT
GTCGCACGTTTAGTAGGACCACCACCAGGTTATGTCGGATATGAAGAAGGAGGCCAATTAACTGAGGCTGTTCGTCAGCG
CTTATACTCTATCGTCCTACTTGATGAGATTGAAAAAGCTCATCCTGATGTTTTTAATACCTTACTGCAGGTTTTAGATG
AAGGGCGTTTGACGGATTCAAAAGGGCGAACCATTGATTTTAAAAATACCATCTTAATTATGACCAGCAATATTGGCTCA
ACCAATATTTTACAAAGTCTGCAAGATAGTGGCTGCATTACTTCAGAAGTCCGTCATAAAGTTCTAGATGAGCTGAATCA
CAGTTTCAGGCCAGAGTTTCTTAATCGGATTGATGAGACGGTACTCTTTAATGCTCTTTCTGAAAAAGATATGACAGGTG
TTGTTAAGGTCATGGTTTCTGATTTGCAAGCTCGCCTCTTAGAACAAGATGTTCATCTGACATTGACTGAATCGGTTTAT
ACCCTCTTAGCTAAAGAAGGTTTTGATGCAGCTTTTGGTGCCAGACCCATGCAGAGGACAATTATGCAAAAGTTAGAAAA
CCCTTTGGCTTTACATCTTATTCAAAATCAGAAAAATAAAGAAAAAGAGACTTTTGTGACAGTATCTGTTAAGGATAAGA
AACTCAAATTCACATTCTCATAG

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (205-338)

• AAA domain (Cdc48 subfamily) (AAA_2) (594-759)

• AAA lid domain (AAA_lid_9) (346-436)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-842)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-144)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (16-66)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	41.02	100	0.412
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	37.175	100	0.383
clpC	Streptococcus pneumoniae Rx1	38.037	94.767	0.36
clpC	Streptococcus pneumoniae D39	38.037	94.767	0.36
clpC	Streptococcus pneumoniae TIGR4	38.177	94.419	0.36