Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HCU70_RS09235 Genome accession   NZ_CP050690
Coordinates   1892177..1892893 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain PMB179-1     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1887177..1897893
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCU70_RS09215 (HCU70_09215) - 1888269..1889219 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  HCU70_RS09220 (HCU70_09220) - 1889368..1890852 (+) 1485 WP_000141411.1 sucrose-6-phosphate hydrolase -
  HCU70_RS09225 (HCU70_09225) - 1890849..1891808 (+) 960 WP_001253291.1 carbohydrate kinase -
  HCU70_RS09230 (HCU70_09230) - 1891996..1892105 (-) 110 Protein_1807 hypothetical protein -
  HCU70_RS09235 (HCU70_09235) agrA 1892177..1892893 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  HCU70_RS09240 (HCU70_09240) - 1892912..1894195 (-) 1284 WP_000447888.1 sensor histidine kinase -
  HCU70_RS09245 (HCU70_09245) - 1894225..1894368 (-) 144 WP_001094921.1 cyclic lactone autoinducer peptide -
  HCU70_RS09250 (HCU70_09250) - 1894371..1894934 (-) 564 WP_001105696.1 accessory gene regulator ArgB-like protein -
  HCU70_RS13600 hld 1895224..1895304 (+) 81 WP_000046022.1 delta-hemolysin -
  HCU70_RS09260 (HCU70_09260) - 1895904..1896689 (-) 786 WP_167774999.1 carbon-nitrogen family hydrolase -
  HCU70_RS09265 (HCU70_09265) - 1897050..1897676 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=433947 HCU70_RS09235 WP_000688498.1 1892177..1892893(-) (agrA) [Staphylococcus aureus strain PMB179-1]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=433947 HCU70_RS09235 WP_000688498.1 1892177..1892893(-) (agrA) [Staphylococcus aureus strain PMB179-1]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996