Detailed information NTG0433943

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: HCU70_RS06150
• Genome accession: NZ_CP050690
• Coordinates: 1286652..1287539 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143417.1
• Uniprot ID: A0A641A7I7
• Organism: Staphylococcus aureus strain PMB179-1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1281652..1292539

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HCU70_RS06120 (HCU70_06120)	-	1282384..1283145 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
HCU70_RS06125 (HCU70_06125)	-	1283390..1283845 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
HCU70_RS13670	-	1283967..1284068 (+)	102	WP_000731972.1	SE2200 family small protein	-
HCU70_RS06135 (HCU70_06135)	-	1284128..1285552 (-)	1425	WP_000953748.1	alkaline phosphatase	-
HCU70_RS06140 (HCU70_06140)	-	1285750..1285950 (+)	201	WP_000604727.1	hypothetical protein	-
HCU70_RS06145 (HCU70_06145)	braR	1285976..1286641 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
HCU70_RS06150 (HCU70_06150)	braS	1286652..1287539 (+)	888	WP_000143417.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
HCU70_RS06155 (HCU70_06155)	-	1287647..1288402 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
HCU70_RS06160 (HCU70_06160)	-	1288399..1290399 (+)	2001	WP_000776740.1	ABC transporter permease	-
HCU70_RS06165 (HCU70_06165)	-	1291058..1291171 (+)	114	Protein_1207	hypothetical protein	-
HCU70_RS06170 (HCU70_06170)	-	1291553..1291813 (+)	261	WP_001791974.1	hypothetical protein	-
HCU70_RS06175 (HCU70_06175)	-	1291823..1292320 (+)	498	WP_001065268.1	glutathione peroxidase	-
HCU70_RS06180 (HCU70_06180)	-	1292428..1292520 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34027.28 Da
• Isoelectric Point: 5.8962

>NTDB_id=433943 HCU70_RS06150 WP_000143417.1 1286652..1287539(+) (braS) [Staphylococcus aureus strain PMB179-1]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLLIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=433943 HCU70_RS06150 WP_000143417.1 1286652..1287539(+) (braS) [Staphylococcus aureus strain PMB179-1]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTACTGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (192-294)

3D structure

• AlphaFold DB: A0A641A7I7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	98.983	100	0.99