Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HC354_RS12845 Genome accession   NZ_CP050650
Coordinates   2625378..2627186 (-) Length   602 a.a.
NCBI ID   WP_002309974.1    Uniprot ID   A0AAW9N0L2
Organism   Enterococcus faecium strain BIOPOP-3 WT     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 2620378..2632186
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HC354_RS12820 (HC354_12820) - 2621425..2622324 (-) 900 WP_002335218.1 RluA family pseudouridine synthase -
  HC354_RS12825 (HC354_12825) - 2622326..2623123 (-) 798 WP_002315658.1 NAD kinase -
  HC354_RS12830 (HC354_12830) - 2623098..2623805 (-) 708 WP_002309982.1 GTP pyrophosphokinase family protein -
  HC354_RS12835 (HC354_12835) - 2623936..2624511 (+) 576 WP_002314142.1 CYTH domain-containing protein -
  HC354_RS12840 (HC354_12840) - 2624629..2625306 (+) 678 WP_002309978.1 ClpXP adapter SpxH family protein -
  HC354_RS12845 (HC354_12845) pepF 2625378..2627186 (-) 1809 WP_002309974.1 oligoendopeptidase F Regulator
  HC354_RS12850 (HC354_12850) - 2627365..2628363 (-) 999 WP_167778943.1 competence protein CoiA family protein -
  HC354_RS12855 (HC354_12855) - 2628461..2629114 (-) 654 WP_002309970.1 adaptor protein MecA -
  HC354_RS12860 (HC354_12860) spxA 2629446..2629844 (-) 399 WP_002296384.1 transcriptional regulator SpxA -
  HC354_RS12865 (HC354_12865) - 2630609..2631316 (+) 708 WP_167778944.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 602 a.a.        Molecular weight: 69695.09 Da        Isoelectric Point: 4.7352

>NTDB_id=433905 HC354_RS12845 WP_002309974.1 2625378..2627186(-) (pepF) [Enterococcus faecium strain BIOPOP-3 WT]
MEVKQLPKREELPENLTWDLTKIFSSDKEFDEKYLELSEKLKKSEKYKGTLNQGASQFLDAIEFVLSVYRQTEIIYVYAH
LKNDQDTGNTEYQALYARASSLFSKVSEAVSWFEPEILQLSDERIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSADQESL
LAGAGEIFEASSDTFAVLNNADLVFPTIEGENGEKVQLSHGVYGQLLESTDRSVREAAFKGLYSVYEQFRNTFASTLSTH
IKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVDVVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTY
EEAKEKALEALKPMGEEYMTIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHEMGHSVHSY
FTRSSQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHYLDGFKGTVFRQTQFAEFEHFMHTEDEKGVP
LTSEYLSDSYGKLNAKYYGPAVEEDPEIKFEWSRIPHFYYNYYVFQYSTGFSAASALAKRILSQEPDALENYLAYLKAGN
SDYPVEVMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL

Nucleotide


Download         Length: 1809 bp        

>NTDB_id=433905 HC354_RS12845 WP_002309974.1 2625378..2627186(-) (pepF) [Enterococcus faecium strain BIOPOP-3 WT]
ATGGAAGTAAAGCAGTTGCCAAAACGCGAAGAATTGCCTGAAAATTTAACTTGGGACTTGACCAAGATCTTTTCAAGCGA
CAAAGAATTTGATGAGAAATATCTAGAATTATCAGAAAAGTTAAAAAAATCTGAAAAATATAAAGGAACACTTAATCAAG
GCGCTTCTCAATTTCTTGATGCGATTGAATTTGTGTTGAGTGTTTATCGCCAAACCGAAATCATTTATGTCTATGCACAC
CTTAAAAACGATCAAGATACTGGGAATACAGAATATCAAGCGCTTTATGCAAGAGCAAGTAGTTTGTTTTCAAAGGTTAG
TGAAGCTGTTTCCTGGTTTGAACCAGAAATATTGCAGTTATCAGATGAACGGATTTGGCAATATTTCAAAGAAGAACCGA
AGTTAGAAGTCTATCGTCACTATATCCAGCAAATAGTAGATAATCGTGCCCATGTTTTATCTGCCGATCAGGAATCGCTT
CTTGCAGGAGCAGGAGAAATCTTTGAGGCTTCAAGTGATACATTTGCTGTTTTGAATAATGCAGATTTAGTTTTCCCAAC
GATCGAAGGAGAGAATGGTGAAAAAGTCCAATTATCTCATGGTGTGTACGGTCAGTTGCTAGAAAGCACGGATCGAAGTG
TTCGCGAAGCCGCATTTAAAGGGTTGTACAGTGTTTATGAGCAATTTAGAAATACGTTTGCTTCTACTTTAAGTACGCAT
ATAAAAGGACATAATTTTAAAGCAAAAGTTCGTAATTACAGCTCTGCCAGAGAAGCATCTTTGAGCAATAATCACATTCC
TGAAAGTGTATACGACACTTTGGTAGATGTAGTAAACAAGCATTTGCCTTTGCTGCATCGATATATGGAATTACGGAAAC
GTTTATTAGAAGTGGAAAAACTGCACATGTACGATCTTTATACACCGGTCTTAGGAGAAGCTCCAATCACCTTTACGTAT
GAAGAAGCAAAAGAGAAAGCTTTGGAAGCACTGAAGCCAATGGGCGAAGAGTACATGACTATTGTAGAAAAAGCATTCTC
TGAACGTTGGATCGATGTTGTCGAAAATAAAGGAAAACGAAGTGGTGCCTATTCTTCGGGAAGCTATGACACAAATCCAT
ATATTTTATTGAATTGGCATGATACATTGGATCAATTGTTTACGCTTGTCCACGAAATGGGACATAGTGTCCACAGTTAT
TTCACACGATCGAGCCAACCTTATGTATACGGTGACTACTCCATCTTTTTAGCAGAAATAGCTTCGACAACGAACGAAAA
TATCCTAACAGAATATTTATTGGAAACAGAAAAAGACCCTCGCGTCCGAGCTTATGTGCTCAACCATTACTTGGATGGAT
TTAAAGGAACAGTTTTCCGCCAGACACAATTTGCTGAATTCGAGCACTTCATGCATACGGAAGATGAAAAAGGTGTGCCA
TTGACTAGTGAATATCTAAGTGATAGTTATGGTAAATTGAATGCAAAATATTATGGTCCGGCAGTCGAAGAAGACCCAGA
AATCAAATTTGAATGGTCACGGATCCCGCATTTTTACTATAATTACTATGTCTTCCAATACTCTACTGGTTTTTCTGCTG
CTTCAGCGTTGGCGAAAAGAATACTTAGTCAGGAACCAGATGCGCTAGAGAACTATTTGGCTTATCTAAAAGCTGGTAAC
AGTGATTATCCTGTTGAAGTGATGAAAAAAGCAGGAGTAGATATGACACAGGCTGCGTATATCGAAGATGCAATGTCGAT
GTTTGAACAACGACTAAACGAATTAGAAGAATTGATTGATCGTTTATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(206-586)

Oligopeptidase F (Peptidase_M3_N)

(116-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

55.649

98.505

0.548