Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   HCC49_RS05615 Genome accession   NZ_CP050462
Coordinates   1070204..1070860 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain Htq6     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1065204..1075860
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HCC49_RS05590 (HCC49_05590) oppF 1065733..1066650 (+) 918 WP_020955632.1 oligopeptide ABC transporter ATP-binding protein OppF -
  HCC49_RS05595 (HCC49_05595) - 1066757..1067944 (+) 1188 WP_053104215.1 putative glycoside hydrolase -
  HCC49_RS05600 (HCC49_05600) - 1068062..1068640 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  HCC49_RS05605 (HCC49_05605) spx 1068819..1069214 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  HCC49_RS05610 (HCC49_05610) - 1069272..1069928 (-) 657 WP_015417213.1 TerC family protein -
  HCC49_RS05615 (HCC49_05615) mecA 1070204..1070860 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  HCC49_RS05620 (HCC49_05620) - 1071011..1072171 (+) 1161 WP_167860048.1 competence protein CoiA family protein -
  HCC49_RS05625 (HCC49_05625) pepF 1072399..1074228 (+) 1830 WP_113629831.1 oligoendopeptidase F Regulator
  HCC49_RS05630 (HCC49_05630) - 1074266..1074433 (-) 168 WP_003155026.1 hypothetical protein -
  HCC49_RS05635 (HCC49_05635) spxH 1074719..1075621 (-) 903 WP_007409106.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=432941 HCC49_RS05615 WP_003155032.1 1070204..1070860(+) (mecA) [Bacillus velezensis strain Htq6]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=432941 HCC49_RS05615 WP_003155032.1 1070204..1070860(+) (mecA) [Bacillus velezensis strain Htq6]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895