Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   Y1U_RS11935 Genome accession   NC_017927
Coordinates   1533221..1534057 (+) Length   278 a.a.
NCBI ID   WP_232973989.1    Uniprot ID   -
Organism   Streptococcus thermophilus MN-ZLW-002     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1528221..1539057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Y1U_RS07970 (Y1U_C1572) - 1528843..1529097 (-) 255 WP_014608660.1 Blp family class II bacteriocin -
  Y1U_RS12230 - 1529348..1529749 (-) 402 WP_024703992.1 hypothetical protein -
  Y1U_RS07985 (Y1U_C1576) - 1530754..1530984 (-) 231 WP_014608662.1 bacteriocin class II family protein -
  Y1U_RS07990 (Y1U_C1577) - 1531340..1531540 (-) 201 WP_011681569.1 hypothetical protein -
  Y1U_RS07995 (Y1U_C1578) - 1531559..1531735 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  Y1U_RS08000 (Y1U_C1579) - 1531986..1532723 (+) 738 WP_011681571.1 LytR/AlgR family response regulator transcription factor -
  Y1U_RS11935 comD/blpH 1533221..1534057 (+) 837 WP_232973989.1 ATP-binding protein Regulator
  Y1U_RS08010 (Y1U_C1581) - 1534075..1534236 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  Y1U_RS08015 (Y1U_C1582) comB 1534251..1535618 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  Y1U_RS08020 (Y1U_C1583) comA/nlmT 1535634..1537787 (-) 2154 WP_014727675.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 278 a.a.        Molecular weight: 32011.66 Da        Isoelectric Point: 4.7428

>NTDB_id=43179 Y1U_RS11935 WP_232973989.1 1533221..1534057(+) (comD/blpH) [Streptococcus thermophilus MN-ZLW-002]
MFGYTLLLQSLMYLENTTHSSTLELRKLCIVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNS
VRSFRHDYSNLLVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQI
SIPEPIHLIGMETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFERGVSNKGRER
GIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 837 bp        

>NTDB_id=43179 Y1U_RS11935 WP_232973989.1 1533221..1534057(+) (comD/blpH) [Streptococcus thermophilus MN-ZLW-002]
ATGTTTGGGTACACCCTACTGTTACAGTCCCTCATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAA
ACTCTGTATTGTTATTTCACTTGTCCTCTTCTTCATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAG
GACAATTGGACTTCCAGAAAAATCTCCAGCTAGAGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCT
GTTCGTAGTTTTAGACACGATTATAGTAATCTCTTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGT
CAAAGAAGTCTATGATAGTGTGCTTCAAGAATCCGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTA
ATATTCAGGATAATACTTTGAAAAGCCTTCTGTCCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATT
AGCATCCCAGAACCCATCCACTTGATTGGGATGGAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGC
TATTGAAGGTGCCATTCAAACTCAAAACCCTAAAATTACTATTAGCTTTTGGGAAGATCATTGTTCACAGCTATTATCTA
TTAGCAATACCATAAGTGAAGAAAAAACAGAAACCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGA
GGCATTGGCCTTGCTAATGTCACAGAAATCTTAGATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTC
ATTCACACAACAATTAACAATAACTAAAAAGGCCTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(171-274)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

37.591

98.561

0.371

Multiple sequence alignment