Detailed information NTG0043130

Bioinformatically predicted

Overview

• Name: vraR
• Type: Regulator
• Locus tag: Y1U_RS06770
• Genome accession: NC_017927
• Coordinates: 1293476..1294120 (-)
• Length: 214 a.a.
• NCBI ID: WP_002951384.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus MN-ZLW-002
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1288476..1299120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Y1U_RS06745 (Y1U_C1321)	-	1290577..1291575 (-)	999	WP_014608529.1	NAD(P)/FAD-dependent oxidoreductase	-
Y1U_RS06750 (Y1U_C1322)	trmD	1291577..1292296 (-)	720	WP_011226285.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
Y1U_RS06755 (Y1U_C1323)	rimM	1292286..1292804 (-)	519	WP_011226286.1	ribosome maturation factor RimM	-
Y1U_RS06770 (Y1U_C1324)	vraR	1293476..1294120 (-)	645	WP_002951384.1	response regulator transcription factor	Regulator
Y1U_RS06775 (Y1U_C1325)	-	1294110..1295120 (-)	1011	WP_011227402.1	sensor histidine kinase	-
Y1U_RS06780 (Y1U_C1326)	liaF	1295117..1295815 (-)	699	WP_014621793.1	cell wall-active antibiotics response protein LiaF	-
Y1U_RS11905 (Y1U_C1327)	-	1296070..1296237 (-)	168	WP_014727613.1	potassium channel family protein	-
Y1U_RS06785 (Y1U_C1328)	stkP/pknB	1296872..1298743 (-)	1872	WP_014727614.1	Stk1 family PASTA domain-containing Ser/Thr kinase	Regulator

Sequence

Protein

• Length: 214 a.a.
• Molecular weight: 24048.39 Da
• Isoelectric Point: 4.5864

>NTDB_id=43130 Y1U_RS06770 WP_002951384.1 1293476..1294120(-) (vraR) [Streptococcus thermophilus MN-ZLW-002]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide

• Length: 645 bp

>NTDB_id=43130 Y1U_RS06770 WP_002951384.1 1293476..1294120(-) (vraR) [Streptococcus thermophilus MN-ZLW-002]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCATGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-118)

• Bacterial regulatory proteins, luxR family (GerE) (149-203)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraR	Staphylococcus aureus N315	50.485	96.262	0.486
degU	Bacillus subtilis subsp. subtilis str. 168	36.161	100	0.379