Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   ILP78_RS11485 Genome accession   NZ_CP062465
Coordinates   2298870..2299544 (-) Length   224 a.a.
NCBI ID   WP_001166500.1    Uniprot ID   Q99VW2
Organism   Staphylococcus aureus strain MRSA - AMRF 6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2293870..2304544
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ILP78_RS11470 (ILP78_11470) vraG 2295053..2296942 (-) 1890 WP_000143612.1 ABC transporter permease VraG -
  ILP78_RS11475 (ILP78_11475) vraF 2296932..2297693 (-) 762 WP_000985996.1 ABC transporter ATP-binding protein VraF -
  ILP78_RS11480 (ILP78_11480) graS 2297837..2298877 (-) 1041 WP_001061247.1 histidine kinase GraS/ApsS -
  ILP78_RS11485 (ILP78_11485) braR 2298870..2299544 (-) 675 WP_001166500.1 response regulator transcription factor GraR/ApsR Regulator
  ILP78_RS11490 (ILP78_11490) graX 2299560..2300483 (-) 924 WP_000802955.1 auxiliary protein GraX/ApsX -
  ILP78_RS11495 (ILP78_11495) - 2300596..2301102 (+) 507 WP_000940129.1 GNAT family N-acetyltransferase -
  ILP78_RS11500 (ILP78_11500) - 2301311..2301667 (-) 357 Protein_2243 hypothetical protein -
  ILP78_RS11505 (ILP78_11505) - 2301888..2302424 (-) 537 WP_078056058.1 IS30 family transposase -
  ILP78_RS11510 (ILP78_11510) - 2302405..2302908 (-) 504 WP_000746372.1 transposase -
  ILP78_RS11515 (ILP78_11515) - 2303017..2303373 (-) 357 WP_001255379.1 cystatin-like fold lipoprotein -
  ILP78_RS11520 (ILP78_11520) - 2303429..2304019 (-) 591 WP_031883302.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 26065.87 Da        Isoelectric Point: 4.3563

>NTDB_id=431085 ILP78_RS11485 WP_001166500.1 2298870..2299544(-) (braR) [Staphylococcus aureus strain MRSA - AMRF 6]
MQILLVEDDNTLFQELKKELEQWDFNVAGIEDFGKVMDTFESFNPEIVILDVQLPKYDGFYWCRKMREVSNVPILFLSSR
DNPMDQVMSMELGADDYMQKPFYTNVLIAKLQAIYRRVYEFTAEEKRTLTWQDAVVDLSKDSIQKGDDTIFLSKTEMIIL
EILITKKNQIVSRDTIITALWDDEAFVSDNTLTVNVNRLRKKLSEISMDSAIETKVGKGYMAHE

Nucleotide


Download         Length: 675 bp        

>NTDB_id=431085 ILP78_RS11485 WP_001166500.1 2298870..2299544(-) (braR) [Staphylococcus aureus strain MRSA - AMRF 6]
ATGCAAATACTACTAGTAGAAGATGACAATACTTTGTTTCAAGAATTGAAAAAAGAATTAGAACAATGGGATTTTAATGT
TGCTGGTATTGAAGATTTCGGCAAAGTAATGGATACATTTGAAAGTTTTAATCCTGAAATTGTTATATTGGATGTTCAAT
TACCTAAATATGATGGGTTTTATTGGTGCAGAAAAATGAGAGAAGTTTCCAACGTACCAATATTATTTTTATCATCTCGT
GATAATCCAATGGATCAAGTGATGAGTATGGAACTTGGCGCAGATGATTATATGCAAAAACCGTTCTATACCAATGTATT
AATTGCTAAATTACAAGCGATTTATCGTCGTGTCTATGAGTTTACAGCTGAAGAAAAACGTACATTGACTTGGCAAGATG
CTGTCGTTGATCTATCAAAAGATAGTATACAAAAAGGTGACGATACGATTTTTCTATCCAAAACAGAAATGATTATATTA
GAAATTCTTATTACCAAAAAAAATCAAATCGTTTCGAGAGATACAATTATCACTGCATTATGGGATGATGAAGCATTTGT
TAGTGATAATACGTTAACAGTAAATGTGAATCGTTTACGAAAAAAATTATCTGAAATAAGTATGGATAGTGCAATCGAAA
CAAAAGTAGGAAAAGGATATATGGCTCATGAATAA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(149-221)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q99VW2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

40.455

98.214

0.397