Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   HB753_RS06325 Genome accession   NZ_CP050270
Coordinates   1285736..1287535 (-) Length   599 a.a.
NCBI ID   WP_019804697.1    Uniprot ID   -
Organism   Streptococcus mutans strain S4     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1280736..1292535
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB753_RS06305 (HB753_06305) - 1282347..1282847 (-) 501 WP_002265403.1 LURP-one-related/scramblase family protein -
  HB753_RS06310 (HB753_06310) prsA 1283086..1284087 (-) 1002 WP_002261893.1 peptidylprolyl isomerase PrsA -
  HB753_RS06315 (HB753_06315) - 1284149..1284856 (-) 708 WP_002261894.1 O-methyltransferase -
  HB753_RS06320 (HB753_06320) - 1284906..1285523 (-) 618 WP_002261895.1 HAD-IA family hydrolase -
  HB753_RS06325 (HB753_06325) pepF 1285736..1287535 (-) 1800 WP_019804697.1 oligoendopeptidase F Regulator
  HB753_RS06330 (HB753_06330) - 1287557..1288495 (-) 939 WP_002268795.1 competence protein CoiA -
  HB753_RS06335 (HB753_06335) - 1288800..1289693 (-) 894 WP_002267117.1 alpha/beta hydrolase -
  HB753_RS06340 (HB753_06340) - 1289799..1290080 (-) 282 Protein_1245 hypothetical protein -
  HB753_RS06345 (HB753_06345) - 1290165..1290292 (+) 128 Protein_1246 ArsR/SmtB family transcription factor -
  HB753_RS06350 (HB753_06350) - 1290325..1291293 (-) 969 WP_002285395.1 alcohol dehydrogenase catalytic domain-containing protein -

Sequence

Protein


Download         Length: 599 a.a.        Molecular weight: 69792.42 Da        Isoelectric Point: 4.8113

>NTDB_id=431059 HB753_RS06325 WP_019804697.1 1285736..1287535(-) (pepF) [Streptococcus mutans strain S4]
MSDNRSHIEEKYQWDLTSIFPNDQTWEKEEKSLAKDLEIAVKRAGHLLDSSQSLLEITELYLALSRRLEKLYVYASMKND
QDTTVSYYQELQAKATALIAKFNQTFAFYEPEFMLLSTEKYQDFLADCPDLLPYQHFFEKLFKQKKHVLSQKEEALLAEA
SEIFGAAGETFEILDNADIIFPWVKDETGEEVELSHGNFISLMESKNRKVRQEAYKAMYRIYEQYQHTYAKTLQTNVKVN
NFQAKIRNYKSAREAALAANFIPETVYDTLVEAVHNHLPLLQRYVKLRQNVLGLDDLKMYDIYVPLSEMDMTFTYEAALD
KAEEVLAIFGRDYAERVHRAFRERWIDVRVNKGKRSGAYSGGSYDTNAFILLNWQDTLDNLFTLVHETGHSLHSTFTREN
QPYVYGDYSIFLAEIASTTNENILTETLLKEATDEKQRFAILNHYLDGFKGTVFRQTQFAEFEDLIYKADQAGDVLTSDY
LNNLYADLNEKYYGLSKKNNPEIQYEWARIPHFYYNFYVYQYATGFAAASFLAHKIVHGNQEDKDKYLNYLKAGNSDYPL
NVIAKAGLDMTESTYLDQAFKVFEERLIELEELVEKGID

Nucleotide


Download         Length: 1800 bp        

>NTDB_id=431059 HB753_RS06325 WP_019804697.1 1285736..1287535(-) (pepF) [Streptococcus mutans strain S4]
ATGTCTGATAATCGCAGTCATATTGAAGAAAAATACCAATGGGATTTGACCAGCATTTTTCCAAACGATCAAACTTGGGA
AAAAGAGGAGAAATCTTTAGCTAAGGATTTGGAAATAGCCGTTAAAAGAGCGGGTCATCTGCTTGACTCCAGTCAAAGTC
TGCTGGAGATCACAGAACTTTATCTGGCTTTGAGCCGTCGTTTGGAAAAACTTTATGTTTATGCTTCTATGAAGAATGAC
CAAGACACCACGGTCAGTTACTATCAAGAATTACAAGCTAAGGCAACAGCCTTGATCGCTAAATTTAATCAGACTTTTGC
CTTCTATGAGCCTGAATTTATGCTGTTATCAACAGAAAAATATCAGGATTTTTTGGCAGATTGTCCGGATTTATTGCCTT
ATCAACATTTTTTTGAAAAATTATTCAAACAAAAAAAGCATGTTCTTTCTCAAAAGGAAGAGGCACTTTTGGCTGAAGCC
AGTGAAATTTTTGGTGCTGCTGGTGAAACCTTTGAAATTCTTGACAATGCCGATATTATCTTTCCTTGGGTAAAAGACGA
GACAGGAGAAGAAGTTGAACTATCTCATGGTAATTTCATCAGTTTGATGGAATCCAAAAACCGCAAAGTTCGACAAGAAG
CTTATAAGGCCATGTACAGGATTTATGAGCAGTATCAACACACCTATGCTAAAACGCTGCAAACCAATGTTAAAGTTAAT
AATTTTCAAGCGAAAATCAGAAACTATAAGAGTGCGCGTGAAGCTGCTCTGGCAGCTAATTTTATTCCCGAAACTGTTTA
TGACACTTTAGTAGAAGCGGTCCATAATCACTTACCTTTGTTACAGCGTTATGTGAAGCTAAGGCAAAACGTTTTAGGCC
TTGATGATCTTAAGATGTATGATATTTACGTACCACTCTCAGAAATGGATATGACTTTTACTTATGAAGCAGCCTTGGAC
AAAGCAGAAGAAGTGTTAGCTATTTTTGGGCGAGACTATGCTGAGCGTGTGCATCGTGCATTTAGGGAGCGTTGGATTGA
TGTACGAGTCAATAAAGGCAAGCGTTCAGGCGCTTATTCAGGTGGTTCCTATGACACCAATGCTTTTATATTGCTTAATT
GGCAGGATACTTTGGATAATCTCTTCACTCTTGTTCATGAAACAGGACATTCTTTGCATTCTACTTTTACACGTGAAAAC
CAACCCTATGTTTATGGTGATTATTCTATTTTTCTGGCAGAAATTGCTTCGACAACCAATGAAAATATTTTGACAGAGAC
ACTGCTCAAGGAAGCAACAGATGAGAAACAGCGTTTTGCGATTTTGAATCATTATCTTGATGGTTTCAAAGGAACGGTTT
TCCGCCAAACACAATTTGCAGAATTTGAAGACTTGATTTATAAGGCTGATCAAGCAGGTGACGTTTTGACCAGTGATTAT
TTGAATAATCTCTATGCGGATCTCAATGAAAAATACTATGGTTTAAGCAAGAAAAATAATCCGGAAATTCAGTATGAATG
GGCTAGGATTCCGCATTTCTATTACAATTTTTATGTTTATCAGTATGCCACAGGCTTTGCTGCAGCTAGTTTTTTGGCTC
ACAAAATTGTTCATGGCAATCAAGAAGATAAGGACAAATATCTCAATTATCTCAAAGCTGGCAATTCAGACTATCCTCTC
AATGTTATTGCTAAAGCAGGTCTTGATATGACTGAGTCGACCTATCTTGACCAAGCCTTCAAAGTCTTTGAAGAACGGTT
AATAGAGTTGGAAGAGTTGGTCGAAAAAGGAATTGATTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

69.398

99.833

0.693