Detailed information NTG0430815

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: IF696_RS10660
• Genome accession: NZ_CP062420
• Coordinates: 2165996..2168101 (-)
• Length: 701 a.a.
• NCBI ID: WP_001058992.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NAS_AN_016
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2160996..2173101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF696_RS10645 (IF696_10560)	-	2163518..2163745 (+)	228	WP_000932073.1	ferrous iron transport protein A	-
IF696_RS10650 (IF696_10565)	feoB	2163757..2165751 (+)	1995	WP_000432899.1	ferrous iron transport protein B	-
IF696_RS10655 (IF696_10570)	-	2165764..2165934 (+)	171	WP_000111119.1	FeoB-associated Cys-rich membrane protein	-
IF696_RS10660 (IF696_10575)	clpE	2165996..2168101 (-)	2106	WP_001058992.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
IF696_RS10665 (IF696_10580)	-	2168510..2169031 (+)	522	WP_000455994.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
IF696_RS10670 (IF696_10585)	-	2169196..2170362 (-)	1167	WP_000151982.1	hydroxymethylglutaryl-CoA synthase	-
IF696_RS10675 (IF696_10590)	-	2170616..2171896 (+)	1281	WP_001180331.1	hydroxymethylglutaryl-CoA reductase, degradative	-
IF696_RS10680 (IF696_10595)	-	2172034..2172465 (-)	432	WP_000455861.1	CHAP domain-containing protein	-
IF696_RS10685 (IF696_10600)	-	2172855..2173073 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 701 a.a.
• Molecular weight: 77864.27 Da
• Isoelectric Point: 4.6056

>NTDB_id=430815 IF696_RS10660 WP_001058992.1 2165996..2168101(-) (clpE) [Staphylococcus aureus strain NAS_AN_016]
MNNGFFNSDFDSIFRRMMQDMQGSNQVGNKKYYINGKEVSPEELAQLTQQGGNHSAEQSAQAFQQAAQRQQGQQGGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLVQAIVEGNVPAAIKDKEIISV
DISSLEAGTQYRGAFEENIQKLIEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNILKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKDA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGNDAEEKDIMHEMKKFFRPEFLNRFNGIVEFLHLDKDALQDIVNLLLDDVQVTLDKKGITMDV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDIDVEDNELVVKGK

Nucleotide

• Length: 2106 bp

>NTDB_id=430815 IF696_RS10660 WP_001058992.1 2165996..2168101(-) (clpE) [Staphylococcus aureus strain NAS_AN_016]
ATGAATAACGGTTTTTTCAATAGTGACTTTGATTCAATTTTTCGAAGAATGATGCAAGATATGCAAGGTTCAAATCAAGT
CGGTAACAAAAAGTACTATATTAATGGTAAAGAAGTTTCACCTGAAGAACTAGCGCAACTCACACAACAAGGTGGCAATC
ACTCTGCTGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACAAAGACAACAAGGGCAACAAGGTGGCAACGGCAATTAT
TTAGAACAAATTGGTCGTAACCTTACGCAAGAAGCACGTGACGGTTTATTAGATCCAGTCATTGGTCGTGATAAAGAAAT
TCAAGAAACTGCTGAAGTCTTAAGTAGACGAACTAAAAACAATCCTATATTAGTTGGAGAAGCTGGTGTTGGTAAAACTG
CGATTGTTGAAGGTTTAGTACAGGCAATCGTTGAAGGAAATGTACCAGCAGCAATCAAAGACAAAGAAATTATTTCTGTA
GATATTTCATCATTAGAAGCTGGAACGCAATATCGTGGTGCTTTTGAAGAAAATATTCAAAAATTAATCGAAGGTGTTAA
ATCTTCACAAAATGCCGTACTATTCTTTGATGAAATCCATCAAATTATCGGTTCAGGTGCCACAGGAAGTGATTCAGGTA
GCAAAGGGTTATCTGATATTTTGAAACCTGCATTAAGTCGTGGTGAGATTTCTATTATTGGTGCAACAACACAAGATGAA
TATCGAAACAATATTCTTAAAGATGCTGCATTAACGCGCAGATTTAATGAAGTACTTGTTAATGAACCAAGTGCTAAAGA
TACTGTGGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTAAAATTACCAGATGACGTATTAAAAG
CATGTGTTGACTTATCAATTCAATATATTCCACAACGATTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCGGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATTAAATCATTACAAGATAAATTAGAAA
ATAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATAGGTCAAGATCA
AGCTGTAGAAATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGGTTTGATGACGGCAACCGTCCAATTGGCAGTTTCC
TATTTGTTGGCCCTACTGGTGTTGGTAAAACAGAGCTTGCTAAACAATTAGCAATTGATCTATTTGGTAATAAAGATGCA
CTGATTCGACTTGATATGAGTGAATATAGTGACACAACAGCTGTTTCAAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGATGACAATTCAAATACGTTAACTGAAAAAGTACGCCGTAATCCATACTCAGTCATTCTATTTGATGAAATCGAAA
AAGCAAATCCACAAATTTTAACATTGTTATTACAAGTAATGGATGATGGTAATTTGACTGATGGTCAAGGTAATGTCATC
AACTTTAAAAATACAATTATTATTTGTACATCAAATGCTGGCTTTGGCAATGGTAATGACGCTGAAGAAAAAGATATTAT
GCACGAAATGAAAAAATTCTTCCGCCCTGAATTCCTTAACCGCTTCAACGGCATCGTTGAATTCTTACATTTAGATAAAG
ATGCATTGCAAGATATCGTCAACTTATTATTAGACGATGTACAAGTTACATTAGACAAAAAAGGTATTACGATGGACGTT
TCTCAAGATGCGAAAGATTGGTTAATTGAAGAAGGCTATGATGAAGAATTAGGTGCACGTCCATTAAGACGTATTGTTGA
ACAGCAAGTACGTGACAAAATTACAGATTATTATCTAGATCATACAGACGTTAAACATGTGGATATAGATGTTGAGGATA
ACGAATTAGTCGTAAAAGGTAAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (264-363)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.678	91.726	0.447
clpE	Streptococcus pneumoniae Rx1	48.136	88.017	0.424
clpE	Streptococcus pneumoniae D39	48.136	88.017	0.424
clpE	Streptococcus pneumoniae R6	48.136	88.017	0.424
clpE	Streptococcus pneumoniae TIGR4	48.136	88.017	0.424
clpC	Lactococcus lactis subsp. cremoris KW2	46.656	89.586	0.418
clpC	Bacillus subtilis subsp. subtilis str. 168	44.41	93.153	0.414
clpC	Streptococcus thermophilus LMD-9	44.234	90.3	0.399
clpC	Streptococcus thermophilus LMG 18311	43.918	90.3	0.397
clpC	Streptococcus pneumoniae TIGR4	44.013	88.16	0.388
clpC	Streptococcus pneumoniae Rx1	44.013	88.16	0.388
clpC	Streptococcus pneumoniae D39	44.013	88.16	0.388
clpC	Streptococcus mutans UA159	43.415	87.732	0.381
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.14	92.582	0.381