Detailed information NTG0430736

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: IF697_RS13415
• Genome accession: NZ_CP062419
• Coordinates: 2728082..2728795 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain NAS_AN_023
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2723082..2733795

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF697_RS13385 (IF697_13310)	sph	2723860..2724690 (-)	831	Protein_2599	sphingomyelin phosphodiesterase	-
IF697_RS13390 (IF697_13315)	-	2724741..2725778 (-)	1038	WP_000857191.1	site-specific integrase	-
IF697_RS13395 (IF697_13320)	-	2725837..2726301 (-)	465	WP_000825947.1	hypothetical protein	-
IF697_RS13400 (IF697_13325)	-	2726401..2726583 (-)	183	WP_000705248.1	hypothetical protein	-
IF697_RS13405 (IF697_13330)	-	2726787..2727128 (-)	342	WP_000591749.1	hypothetical protein	-
IF697_RS13410 (IF697_13335)	-	2727134..2728066 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
IF697_RS13415 (IF697_13340)	irvR	2728082..2728795 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
IF697_RS13420 (IF697_13345)	-	2728758..2728931 (+)	174	WP_240122453.1	transcriptional regulator	-
IF697_RS13425 (IF697_13350)	-	2728928..2729191 (+)	264	WP_000854073.1	helix-turn-helix transcriptional regulator	-
IF697_RS13430 (IF697_13355)	-	2729207..2729404 (+)	198	WP_001148862.1	hypothetical protein	-
IF697_RS13435 (IF697_13360)	-	2729391..2729771 (-)	381	WP_000762519.1	DUF2513 domain-containing protein	-
IF697_RS13440 (IF697_13365)	-	2729826..2730149 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
IF697_RS13445 (IF697_13370)	-	2730146..2730307 (+)	162	WP_000048129.1	DUF1270 family protein	-
IF697_RS13450 (IF697_13375)	-	2730402..2730704 (+)	303	WP_000165371.1	DUF2482 family protein	-
IF697_RS13455 (IF697_13380)	-	2730709..2730969 (+)	261	WP_000291510.1	DUF1108 family protein	-
IF697_RS13460 (IF697_13385)	-	2730978..2731241 (+)	264	WP_001205732.1	hypothetical protein	-
IF697_RS13465 (IF697_13390)	-	2731250..2733193 (+)	1944	WP_000700555.1	AAA family ATPase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=430736 IF697_RS13415 WP_001031454.1 2728082..2728795(-) (irvR) [Staphylococcus aureus strain NAS_AN_023]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=430736 IF697_RS13415 WP_001031454.1 2728082..2728795(-) (irvR) [Staphylococcus aureus strain NAS_AN_023]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCTTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401