Detailed information NTG0430289

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: IF723_RS13435
• Genome accession: NZ_CP062414
• Coordinates: 2732709..2733422 (-)
• Length: 237 a.a.
• NCBI ID: WP_001031454.1
• Uniprot ID: A0A0H2XG68
• Organism: Staphylococcus aureus strain NAS_AN_175
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2727709..2738422

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF723_RS13405 (IF723_13300)	sph	2728273..2729103 (-)	831	Protein_2603	sphingomyelin phosphodiesterase	-
IF723_RS13410 (IF723_13305)	-	2729154..2730191 (-)	1038	WP_240100856.1	site-specific integrase	-
IF723_RS13415 (IF723_13310)	-	2730364..2730903 (-)	540	WP_000391618.1	type II toxin-antitoxin system PemK/MazF family toxin	-
IF723_RS13420 (IF723_13315)	-	2731043..2731210 (-)	168	WP_031806878.1	hypothetical protein	-
IF723_RS13425 (IF723_13320)	-	2731414..2731755 (-)	342	WP_000591749.1	hypothetical protein	-
IF723_RS13430 (IF723_13325)	-	2731761..2732693 (-)	933	WP_000759682.1	exonuclease domain-containing protein	-
IF723_RS13435 (IF723_13330)	irvR	2732709..2733422 (-)	714	WP_001031454.1	XRE family transcriptional regulator	Regulator
IF723_RS13440 (IF723_13335)	-	2733385..2733558 (+)	174	WP_001801500.1	hypothetical protein	-
IF723_RS13445 (IF723_13340)	-	2733555..2733818 (+)	264	WP_000854072.1	helix-turn-helix transcriptional regulator	-
IF723_RS13450 (IF723_13345)	-	2733834..2734031 (+)	198	WP_001148862.1	hypothetical protein	-
IF723_RS13455 (IF723_13350)	-	2734018..2734398 (-)	381	WP_000762521.1	DUF2513 domain-containing protein	-
IF723_RS13460 (IF723_13355)	-	2734453..2734776 (+)	324	WP_001120201.1	DUF771 domain-containing protein	-
IF723_RS13465 (IF723_13360)	-	2734773..2734934 (+)	162	WP_000048132.1	DUF1270 family protein	-
IF723_RS13470 (IF723_13365)	-	2735029..2735331 (+)	303	WP_000165371.1	DUF2482 family protein	-
IF723_RS13475 (IF723_13370)	-	2735336..2735596 (+)	261	WP_000291510.1	DUF1108 family protein	-
IF723_RS13480 (IF723_13375)	-	2735605..2735868 (+)	264	WP_001205732.1	hypothetical protein	-
IF723_RS13485 (IF723_13380)	-	2735877..2737820 (+)	1944	WP_000700555.1	AAA family ATPase	-

Sequence

Protein

• Length: 237 a.a.
• Molecular weight: 27017.58 Da
• Isoelectric Point: 5.0545

>NTDB_id=430289 IF723_RS13435 WP_001031454.1 2732709..2733422(-) (irvR) [Staphylococcus aureus strain NAS_AN_175]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide

• Length: 714 bp

>NTDB_id=430289 IF723_RS13435 WP_001031454.1 2732709..2733422(-) (irvR) [Staphylococcus aureus strain NAS_AN_175]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTACGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

• Peptidase S24-like (Peptidase_S24) (127-236)

• Helix-turn-helix (HTH_3) (13-63)

3D structure

• AlphaFold DB: A0A0H2XG68

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	33.929	100	0.401