Detailed information NTG0428457

Bioinformatically predicted

Overview

• Name: hexB
• Type: Machinery gene
• Locus tag: IF700_RS03645
• Genome accession: NZ_CP062388
• Coordinates: 723331..725340 (-)
• Length: 669 a.a.
• NCBI ID: WP_000516269.1
• Uniprot ID: B1VK93
• Organism: Staphylococcus aureus strain NAS_AN_044
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 718331..730340

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF700_RS03630 (IF700_03625)	glpK	719865..721361 (-)	1497	WP_000417372.1	glycerol kinase GlpK	-
IF700_RS03635 (IF700_03630)	-	721490..722308 (-)	819	WP_001103743.1	MIP/aquaporin family protein	-
IF700_RS03640 (IF700_03635)	-	722783..723325 (-)	543	WP_001077635.1	glycerol-3-phosphate responsive antiterminator	-
IF700_RS03645 (IF700_03640)	hexB	723331..725340 (-)	2010	WP_000516269.1	DNA mismatch repair endonuclease MutL	Machinery gene
IF700_RS03650 (IF700_03645)	hexA	725353..727971 (-)	2619	WP_000073352.1	DNA mismatch repair protein MutS	Machinery gene
IF700_RS03655 (IF700_03650)	thiW	728274..728765 (-)	492	WP_000842277.1	energy coupling factor transporter S component ThiW	-
IF700_RS03660 (IF700_03655)	-	728792..729157 (-)	366	WP_000282386.1	RicAFT regulatory complex protein RicA family protein	-

Sequence

Protein

• Length: 669 a.a.
• Molecular weight: 76871.06 Da
• Isoelectric Point: 5.0107

>NTDB_id=428457 IF700_RS03645 WP_000516269.1 723331..725340(-) (hexB) [Staphylococcus aureus strain NAS_AN_044]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLYSFEQQKIEFEQRQNTENNQEKTFSSEESNSKSFMAENQNDEIVIKEDSYNPFV
TKTSESLITDDESSGYNNTREKDEDYFKKQQEILQEMDQTFDSNEDASVQNYENKASDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide

• Length: 2010 bp

>NTDB_id=428457 IF700_RS03645 WP_000516269.1 723331..725340(-) (hexB) [Staphylococcus aureus strain NAS_AN_044]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGATCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
TAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATACTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAATAGAATGGCTATGAGCCATCCGGACATTCGAATAGC
ACTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGCTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTCCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCAAAAAAAAATAAAGTATTATA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACAGTAAGTCATTTATGGCAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTCGTA
ACGAAAACATCTGAAAGTTTAATAACTGATGATGAATCTTCTGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGATTCAAATGAGGATGCATCTGTGCAAAATTATGAGA
ATAAAGCGTCTGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGGACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAGGATGAACAATTAGTTATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATCAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATTAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATAATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

• MutL C terminal dimerisation domain (MutL_C) (483-625)

• DNA mismatch repair protein, C-terminal domain (DNA_mis_repair) (209-325)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3) (25-118)

3D structure

• AlphaFold DB: B1VK93

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexB	Streptococcus pneumoniae R6	40.828	100	0.413