Detailed information NTG0427353

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: IF722_RS12735
• Genome accession: NZ_CP062360
• Coordinates: 2549324..2551432 (+)
• Length: 702 a.a.
• NCBI ID: WP_098817988.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NAS_AN_157
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2544324..2556432

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IF722_RS12715 (IF722_12665)	-	2544643..2545923 (-)	1281	WP_106875250.1	hydroxymethylglutaryl-CoA reductase, degradative	-
IF722_RS12720 (IF722_12670)	-	2546178..2547344 (+)	1167	WP_000151980.1	hydroxymethylglutaryl-CoA synthase	-
IF722_RS12725 (IF722_12675)	sey	2547573..2548238 (-)	666	WP_072491179.1	staphylococcal enterotoxin type Y	-
IF722_RS12730 (IF722_12680)	-	2548440..2548961 (-)	522	WP_072491178.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
IF722_RS12735 (IF722_12685)	clpE	2549324..2551432 (+)	2109	WP_098817988.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
IF722_RS12740 (IF722_12690)	-	2551499..2551669 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
IF722_RS12745 (IF722_12695)	feoB	2551682..2553676 (-)	1995	WP_000432900.1	ferrous iron transport protein B	-
IF722_RS12750 (IF722_12700)	-	2553688..2553915 (-)	228	WP_000932073.1	ferrous iron transport protein A	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78147.75 Da
• Isoelectric Point: 4.6893

>NTDB_id=427353 IF722_RS12735 WP_098817988.1 2549324..2551432(+) (clpE) [Staphylococcus aureus strain NAS_AN_157]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSARDTVEILKGIREKFEAHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQIPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNATDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEDLGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=427353 IF722_RS12735 WP_098817988.1 2549324..2551432(+) (clpE) [Staphylococcus aureus strain NAS_AN_157]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
CTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACAACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAGAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAGCACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATTGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAATCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACTGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGCTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAAGGTTATGATGAAGACTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (265-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	46.361	90.028	0.417
clpE	Streptococcus pneumoniae Rx1	47.488	87.892	0.417
clpE	Streptococcus pneumoniae D39	47.488	87.892	0.417
clpE	Streptococcus pneumoniae R6	47.488	87.892	0.417
clpE	Streptococcus pneumoniae TIGR4	47.488	87.892	0.417
clpC	Bacillus subtilis subsp. subtilis str. 168	43.884	93.162	0.409
clpC	Streptococcus thermophilus LMD-9	44.48	89.031	0.396
clpC	Streptococcus thermophilus LMG 18311	44.16	89.031	0.393
clpC	Streptococcus pneumoniae TIGR4	43.61	89.174	0.389
clpC	Streptococcus pneumoniae Rx1	43.61	89.174	0.389
clpC	Streptococcus pneumoniae D39	43.61	89.174	0.389
clpC	Streptococcus mutans UA159	43.577	87.607	0.382
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.308	88.889	0.376