Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   IF730_RS13420 Genome accession   NZ_CP062354
Coordinates   2721736..2722449 (-) Length   237 a.a.
NCBI ID   WP_001031454.1    Uniprot ID   A0A0H2XG68
Organism   Staphylococcus aureus strain NAS_AN_206     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2716736..2727449
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF730_RS13385 (IF730_13335) sph 2716738..2717568 (-) 831 Protein_2599 sphingomyelin phosphodiesterase -
  IF730_RS13390 (IF730_13340) - 2717619..2718656 (-) 1038 WP_000857180.1 site-specific integrase -
  IF730_RS13395 (IF730_13345) - 2718719..2718961 (-) 243 WP_000427213.1 hypothetical protein -
  IF730_RS13400 (IF730_13350) - 2718972..2719955 (-) 984 WP_001558608.1 glycosyltransferase family 2 protein -
  IF730_RS13405 (IF730_13355) - 2720055..2720237 (-) 183 WP_000694772.1 hypothetical protein -
  IF730_RS13410 (IF730_13360) - 2720441..2720782 (-) 342 WP_000591749.1 hypothetical protein -
  IF730_RS13415 (IF730_13365) - 2720788..2721720 (-) 933 WP_000759682.1 exonuclease domain-containing protein -
  IF730_RS13420 (IF730_13370) irvR 2721736..2722449 (-) 714 WP_001031454.1 XRE family transcriptional regulator Regulator
  IF730_RS13425 (IF730_13375) - 2722412..2722586 (+) 175 Protein_2607 transcriptional regulator -
  IF730_RS13430 (IF730_13380) - 2722583..2722846 (+) 264 WP_000854072.1 helix-turn-helix transcriptional regulator -
  IF730_RS13435 (IF730_13385) - 2722862..2723077 (+) 216 WP_001025404.1 MW1434 family type I TA system toxin -
  IF730_RS13440 (IF730_13390) - 2723066..2723395 (-) 330 WP_000128909.1 hypothetical protein -
  IF730_RS13445 (IF730_13395) - 2723446..2724198 (+) 753 WP_001148605.1 phage antirepressor KilAC domain-containing protein -
  IF730_RS13450 (IF730_13400) - 2724214..2724411 (+) 198 WP_001148856.1 hypothetical protein -
  IF730_RS13455 (IF730_13405) - 2724442..2724582 (+) 141 WP_000939496.1 hypothetical protein -
  IF730_RS13460 (IF730_13410) - 2724597..2725229 (-) 633 WP_000275058.1 hypothetical protein -
  IF730_RS13465 (IF730_13415) - 2725288..2725608 (+) 321 WP_001120197.1 DUF771 domain-containing protein -
  IF730_RS13470 (IF730_13420) - 2725605..2725766 (+) 162 WP_000066020.1 DUF1270 domain-containing protein -
  IF730_RS13475 (IF730_13425) - 2725859..2726119 (+) 261 WP_000291489.1 DUF1108 family protein -
  IF730_RS13480 (IF730_13430) - 2726129..2726350 (+) 222 WP_000815404.1 DUF2483 domain-containing protein -
  IF730_RS13485 (IF730_13435) - 2726343..2727122 (+) 780 WP_240021883.1 ATP-binding protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27017.58 Da        Isoelectric Point: 5.0545

>NTDB_id=427090 IF730_RS13420 WP_001031454.1 2721736..2722449(-) (irvR) [Staphylococcus aureus strain NAS_AN_206]
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSI
YNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKV
NGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL

Nucleotide


Download         Length: 714 bp        

>NTDB_id=427090 IF730_RS13420 WP_001031454.1 2721736..2722449(-) (irvR) [Staphylococcus aureus strain NAS_AN_206]
ATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACT
TGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATAC
AAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATA
TACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGG
AGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAG
GAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTA
AATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACA
AATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCAC
TAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(127-236)

Helix-turn-helix (HTH_3)

(13-63)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2XG68

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

33.929

100

0.401