Detailed information NTG0042693

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: SMULJ23_RS05295
• Genome accession: NC_017768
• Coordinates: 1073382..1074053 (-)
• Length: 223 a.a.
• NCBI ID: WP_014678012.1
• Uniprot ID: Q8VUH0
• Organism: Streptococcus mutans LJ23
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1068382..1079053

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMULJ23_RS05275 (SMULJ23_1019)	-	1069471..1070160 (+)	690	WP_002269136.1	GntR family transcriptional regulator	-
SMULJ23_RS05280 (SMULJ23_1020)	citG	1070166..1071056 (+)	891	WP_002265082.1	triphosphoribosyl-dephospho-CoA synthase CitG	-
SMULJ23_RS05285 (SMULJ23_1021)	citC	1071232..1072281 (+)	1050	WP_002270831.1	[citrate (pro-3S)-lyase] ligase	-
SMULJ23_RS05290 (SMULJ23_1022)	-	1072432..1073385 (-)	954	WP_002270830.1	sensor histidine kinase	-
SMULJ23_RS05295 (SMULJ23_1023)	braR	1073382..1074053 (-)	672	WP_014678012.1	response regulator transcription factor	Regulator
SMULJ23_RS05300 (SMULJ23_1024)	-	1074095..1076098 (-)	2004	WP_002263238.1	ABC transporter permease	-
SMULJ23_RS05305 (SMULJ23_1025)	-	1076100..1076852 (-)	753	WP_002265085.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 223 a.a.
• Molecular weight: 25828.94 Da
• Isoelectric Point: 5.0036

>NTDB_id=42693 SMULJ23_RS05295 WP_014678012.1 1073382..1074053(-) (braR) [Streptococcus mutans LJ23]
MLKQEKIYLVEDDTTIVNLLKNHLGQHYQVKSVDNFRAILQEVKEFKPDLILMDITLPYFNGFYWTTEIRKSMTMPIIFI
SSADEEMNAVMAMNMGGDDFLSKPFSLPILDAKIAAFLRRANEFTKQGHQIEEFELTLDGVFSNLERQETIQLTPTETKI
LSLLIDYKGEVVTKEALLNRLWEGEEFIDQNTLSVNMTRLRKKVLSVSFDKIYTVRGVGYLIK

Nucleotide

• Length: 672 bp

>NTDB_id=42693 SMULJ23_RS05295 WP_014678012.1 1073382..1074053(-) (braR) [Streptococcus mutans LJ23]
ATGCTAAAGCAAGAAAAAATTTACTTGGTTGAAGATGATACAACCATTGTCAATCTTTTAAAGAATCATTTGGGACAACA
CTATCAAGTTAAAAGCGTTGATAACTTTAGGGCTATCTTGCAAGAAGTTAAAGAATTTAAACCCGATTTAATTCTGATGG
ATATTACTTTGCCCTATTTCAATGGCTTTTATTGGACTACTGAAATCAGAAAGAGCATGACCATGCCCATTATCTTTATT
TCCAGTGCTGATGAAGAAATGAATGCAGTAATGGCTATGAATATGGGAGGTGATGATTTTTTGAGCAAGCCTTTCTCGCT
GCCTATTTTGGATGCCAAAATCGCTGCTTTCTTGCGCCGTGCTAACGAGTTCACTAAGCAAGGCCATCAAATTGAAGAGT
TTGAATTAACGTTAGATGGTGTATTCTCAAATTTAGAAAGACAAGAGACTATCCAATTGACTCCAACAGAAACGAAAATT
CTTTCCTTACTTATTGATTATAAAGGAGAGGTTGTCACTAAGGAAGCTCTTCTCAACCGACTATGGGAGGGAGAGGAATT
TATTGATCAAAACACGCTTAGTGTCAATATGACACGTCTTCGTAAAAAGGTTCTATCAGTAAGTTTTGATAAGATTTATA
CAGTAAGAGGAGTAGGGTATTTAATTAAATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (7-114)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (149-221)

3D structure

• AlphaFold DB: Q8VUH0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	43.498	100	0.435