Detailed information    

insolico Bioinformatically predicted

Overview

Name   treR   Type   Regulator
Locus tag   G8B46_RS08495 Genome accession   NZ_CP049686
Coordinates   1737693..1738406 (+) Length   237 a.a.
NCBI ID   WP_002982243.1    Uniprot ID   A0A9X5LXW4
Organism   Streptococcus pyogenes strain TSPY637     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1732693..1743406
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G8B46_RS08485 (G8B46_08565) treC 1733763..1735391 (-) 1629 WP_011529089.1 alpha,alpha-phosphotrehalase -
  G8B46_RS08490 (G8B46_08570) treP 1735459..1737482 (-) 2024 Protein_1620 PTS system trehalose-specific EIIBC component -
  G8B46_RS08495 (G8B46_08575) treR 1737693..1738406 (+) 714 WP_002982243.1 trehalose operon repressor Regulator
  G8B46_RS08500 (G8B46_08580) - 1738685..1739023 (-) 339 WP_011529091.1 helix-turn-helix domain-containing protein -
  G8B46_RS08505 (G8B46_08585) - 1739209..1740057 (+) 849 Protein_1623 VOC family protein -
  G8B46_RS08510 (G8B46_08590) yaaA 1740099..1740830 (+) 732 WP_219208676.1 peroxide stress protein YaaA -
  G8B46_RS08515 (G8B46_08595) nrdG 1741004..1741618 (-) 615 WP_021299115.1 anaerobic ribonucleoside-triphosphate reductase activating protein -
  G8B46_RS08520 (G8B46_08600) - 1741633..1742127 (-) 495 WP_011055085.1 GNAT family N-acetyltransferase -
  G8B46_RS08525 (G8B46_08605) - 1742136..1743071 (-) 936 WP_021299109.1 Gfo/Idh/MocA family protein -
  G8B46_RS08530 (G8B46_08610) - 1743100..1743246 (-) 147 WP_011106921.1 hypothetical protein -

Sequence

Protein


Download         Length: 237 a.a.        Molecular weight: 27592.78 Da        Isoelectric Point: 9.6226

>NTDB_id=426663 G8B46_RS08495 WP_002982243.1 1737693..1738406(+) (treR) [Streptococcus pyogenes strain TSPY637]
MTKYERIYKDLETKINKDFYKEGDFLPTEIELSQQYQASRDTVRKALSLLTKAGLILKKQGRGTQVIKHHQIMFPISELT
SYQELVSYSNLDSKTNVIAIDKLIVDETLSKLTGFSKNSLVWRVTRQRVVEGVASVLDIDYLSKTLVPIMTREIAEHSIY
QYLEKELHLAIDFALKEVTIDQITDRDKILLDLGSDQHVVSVKSKVYLSNNNQFQFTESRHKLEKFKFLDFARRRPK

Nucleotide


Download         Length: 714 bp        

>NTDB_id=426663 G8B46_RS08495 WP_002982243.1 1737693..1738406(+) (treR) [Streptococcus pyogenes strain TSPY637]
ATGACAAAGTATGAACGTATTTATAAAGACCTCGAAACAAAAATAAACAAAGACTTTTACAAAGAAGGGGATTTTTTACC
TACTGAAATAGAATTGAGTCAACAATACCAAGCTAGCCGAGATACCGTCCGCAAGGCTCTCTCACTTCTCACAAAGGCAG
GTCTTATCCTCAAAAAACAAGGACGTGGCACCCAAGTGATTAAACATCATCAGATCATGTTCCCTATCTCAGAACTAACT
AGTTATCAGGAACTCGTCTCTTACTCAAATCTAGATTCTAAGACCAACGTCATTGCCATTGATAAACTGATTGTGGATGA
GACACTTTCAAAATTGACCGGTTTTAGCAAAAACAGCTTGGTCTGGCGTGTTACGCGCCAACGCGTTGTTGAGGGTGTGG
CTTCCGTCTTAGACATTGATTACCTTAGTAAAACTTTGGTGCCAATAATGACAAGGGAAATCGCAGAGCATTCTATTTAT
CAATATTTGGAAAAGGAACTCCATCTCGCCATTGACTTTGCCCTCAAAGAGGTTACCATTGACCAAATAACCGATCGTGA
TAAAATTTTACTTGACCTTGGATCAGACCAACATGTTGTTTCCGTCAAATCCAAAGTTTACCTTTCCAATAATAACCAAT
TCCAATTCACCGAGAGTCGCCATAAACTGGAAAAATTTAAATTTTTAGATTTTGCTCGGCGCAGACCAAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, gntR family (GntR)

(3-66)

UTRA domain (UTRA)

(91-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  treR Streptococcus mutans UA159

68.803

98.734

0.679