Detailed information NTG0042659

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: TEH_RS07350
• Genome accession: NC_016052
• Coordinates: 1528783..1529826 (-)
• Length: 347 a.a.
• NCBI ID: WP_014124890.1
• Uniprot ID: A0A2H6DQ50
• Organism: Tetragenococcus halophilus NBRC 12172
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1523783..1534826

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
TEH_RS07325 (TEH_15090)	-	1524433..1524894 (-)	462	WP_014124885.1	SprT family protein	-
TEH_RS07330 (TEH_15100)	-	1524891..1527068 (-)	2178	WP_014124886.1	Tex family protein	-
TEH_RS07335 (TEH_15110)	-	1527148..1527882 (-)	735	WP_014124887.1	metallophosphoesterase	-
TEH_RS07340 (TEH_15120)	-	1527912..1528283 (-)	372	WP_014124888.1	VOC family protein	-
TEH_RS07345 (TEH_15130)	-	1528297..1528680 (-)	384	WP_014124889.1	DUF1149 family protein	-
TEH_RS07350 (TEH_15140)	sepM	1528783..1529826 (-)	1044	WP_014124890.1	SepM family pheromone-processing serine protease	Regulator
TEH_RS07355 (TEH_15150)	coaD	1529816..1530310 (-)	495	WP_014124891.1	pantetheine-phosphate adenylyltransferase	-
TEH_RS07360 (TEH_15160)	rsmD	1530313..1530867 (-)	555	WP_041591824.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
TEH_RS07365 (TEH_15170)	-	1530901..1531215 (-)	315	WP_014124893.1	YlbG family protein	-
TEH_RS07370 (TEH_15180)	-	1531205..1531630 (-)	426	WP_014124894.1	YlbF family regulator	-
TEH_RS07375 (TEH_15190)	-	1531627..1532742 (-)	1116	WP_014124895.1	CAP-associated domain-containing protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 38257.23 Da
• Isoelectric Point: 4.5199

>NTDB_id=42659 TEH_RS07350 WP_014124890.1 1528783..1529826(-) (sepM) [Tetragenococcus halophilus NBRC 12172]
MKRDSLKKTLILLIIALAIFASVFLPLPYYIEKPGSTIELKDLITVNDKKDQEDGSFSLTSVGVQQASVVTAIKAKISPF
EELVSEEDLFGGASGEEYDQMQNYYMESSQNAAIQQALKLAKRPYNFEYKGVYVMNVMENSSFNGKIDVGDTVTKVDGKS
FDNNQDFMDYVQQKSIGDTVKVTYEHNDKTKKASGKLVELPSNQKAGIGITLVDHTDITSKDDIDFDVEDIGGPSAGLMF
TLEIYEQLTEEDLRKGKDIAGTGTIDEKGKVGRISGIDKKVASADEAGAQIFFAPNDTISKKVLKKNPGLKSNYQEAKET
ADSLDTDMKIVPVKTLQDAIDYLKQMD

Nucleotide

• Length: 1044 bp

>NTDB_id=42659 TEH_RS07350 WP_014124890.1 1528783..1529826(-) (sepM) [Tetragenococcus halophilus NBRC 12172]
ATGAAGCGTGATTCTTTAAAAAAAACGTTAATACTTTTGATCATTGCACTCGCTATTTTCGCGAGTGTCTTTTTACCTTT
ACCCTATTATATTGAAAAGCCCGGTTCTACAATTGAACTTAAAGATTTAATCACTGTTAATGATAAAAAAGACCAGGAAG
ATGGTTCTTTTTCCCTAACTTCGGTAGGTGTTCAGCAGGCTTCAGTTGTTACAGCAATAAAAGCAAAGATTTCTCCTTTT
GAAGAATTGGTTTCAGAAGAAGATCTTTTCGGTGGGGCGAGTGGTGAAGAATATGATCAGATGCAAAATTATTATATGGA
ATCCTCGCAAAACGCAGCGATTCAACAAGCGCTAAAGTTGGCAAAGCGCCCTTATAACTTTGAGTATAAGGGTGTTTATG
TGATGAATGTGATGGAAAATTCGAGCTTTAATGGAAAAATAGATGTTGGTGACACAGTAACGAAAGTCGATGGAAAAAGC
TTTGATAATAACCAGGATTTTATGGATTATGTTCAGCAAAAGTCAATTGGTGACACTGTAAAAGTAACTTATGAACATAA
TGATAAAACAAAGAAAGCTAGTGGCAAGCTGGTAGAACTACCAAGTAATCAAAAAGCAGGAATCGGCATTACTTTAGTAG
ATCACACAGATATTACTTCAAAAGACGATATTGATTTTGATGTAGAGGATATTGGCGGACCTTCTGCTGGTTTAATGTTT
ACACTAGAAATTTATGAACAACTGACTGAAGAAGATTTGAGAAAAGGAAAAGATATCGCAGGAACAGGTACCATTGATGA
AAAAGGCAAAGTCGGGCGAATCAGTGGTATTGACAAAAAAGTGGCCAGCGCAGATGAAGCAGGTGCGCAAATCTTTTTTG
CGCCCAATGATACAATAAGTAAAAAAGTATTAAAGAAAAACCCCGGCTTAAAATCTAACTATCAGGAAGCTAAAGAGACA
GCTGATAGTTTAGATACGGACATGAAAATCGTTCCGGTAAAAACCTTACAAGATGCTATTGATTATTTAAAACAGATGGA
TTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (233-298)

• PDZ domain (PDZ_2) (130-194)

3D structure

• AlphaFold DB: A0A2H6DQ50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	50.149	96.542	0.484