Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GYO_RS28595 Genome accession   NC_016047
Coordinates   1339200..1339856 (+) Length   218 a.a.
NCBI ID   WP_014113374.1    Uniprot ID   G4NWF3
Organism   Bacillus spizizenii TU-B-10     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1334200..1344856
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GYO_RS28570 (GYO_1451) oppF 1334446..1335363 (+) 918 WP_014113371.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GYO_RS28575 (GYO_1452) - 1335557..1336681 (+) 1125 WP_014113372.1 MFS transporter -
  GYO_RS28580 (GYO_1453) - 1336859..1337437 (+) 579 WP_003224597.1 GNAT family N-acetyltransferase -
  GYO_RS28585 (GYO_1454) spx 1337618..1338013 (+) 396 WP_003239281.1 transcriptional regulator Spx -
  GYO_RS28590 (GYO_1455) - 1338268..1338924 (-) 657 WP_014113373.1 TerC family protein -
  GYO_RS43680 - 1339108..1339233 (+) 126 WP_120698858.1 hypothetical protein -
  GYO_RS28595 (GYO_1456) mecA 1339200..1339856 (+) 657 WP_014113374.1 adaptor protein MecA Regulator
  GYO_RS43685 - 1339851..1339972 (-) 122 Protein_1318 hypothetical protein -
  GYO_RS28600 (GYO_1457) coiA 1340046..1341167 (+) 1122 WP_238528874.1 competence protein CoiA family protein Machinery gene
  GYO_RS28605 (GYO_1458) pepF 1341397..1343226 (+) 1830 WP_166854689.1 oligoendopeptidase F -
  GYO_RS28610 (GYO_1459) - 1343264..1343431 (-) 168 WP_041520918.1 hypothetical protein -
  GYO_RS28620 (GYO_1460) spxH 1343745..1344644 (-) 900 WP_014113378.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25730.60 Da        Isoelectric Point: 4.1174

>NTDB_id=42573 GYO_RS28595 WP_014113374.1 1339200..1339856(+) (mecA) [Bacillus spizizenii TU-B-10]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHEEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPASEDLDALLDDFQKEEQAVNQEEKEQKLQFVLRFGDFEDVISLSKLNVNGSKTTLYSFENR
YYLYVDFGNMTDEEVENQLSILLEYANESSISIHRLEEYGKLIISEHALETIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=42573 GYO_RS28595 WP_014113374.1 1339200..1339856(+) (mecA) [Bacillus spizizenii TU-B-10]
ATGGAAATTGAAAGAATTAACGAGCATACAGTAAAATTTTATATGTCTTACGGAGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTATAACCGTGAACGCAGTGAAGAACTTTTCTGGGAAGTCATGGATGAAGTTCATGAGGAAGAGGAAT
TTGCTGTGGAAGGCCCTCTTTGGATTCAAGTTCAGGCACTGGACAAAGGATTAGAAATCATCGTCACAAAAGCCCAGCTT
TCCAAAGACGGACAAAAGCTCGAACTGCCGATTCCTGAGGATAAAAAGCAAGAACCAGCATCTGAGGATCTTGACGCCTT
GCTGGATGATTTCCAGAAAGAAGAGCAAGCCGTCAATCAGGAAGAGAAGGAGCAAAAGCTTCAATTTGTCTTGCGGTTTG
GCGATTTTGAGGATGTTATTTCTCTATCTAAATTGAACGTTAACGGAAGCAAAACGACTTTATATTCGTTTGAGAACCGA
TATTATTTATATGTAGATTTTGGCAATATGACTGACGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCAAA
TGAATCCTCAATCAGCATACACCGTCTTGAAGAGTACGGCAAGCTGATTATTTCAGAGCATGCTCTGGAAACGATAAAAA
AACACTTTGCATCATAG

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G4NWF3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

99.083

100

0.991

Multiple sequence alignment