Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   G6Z52_RS01425 Genome accession   NZ_CP049187
Coordinates   268385..269455 (+) Length   356 a.a.
NCBI ID   WP_002986002.1    Uniprot ID   Q1JNF7
Organism   Streptococcus pyogenes strain TSPY1687     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 263385..274455
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G6Z52_RS01410 (G6Z52_01415) amiA 263913..265883 (+) 1971 WP_024623426.1 peptide ABC transporter substrate-binding protein Regulator
  G6Z52_RS01415 (G6Z52_01420) amiC 265948..267450 (+) 1503 WP_002991105.1 ABC transporter permease Regulator
  G6Z52_RS01420 (G6Z52_01425) amiD 267450..268376 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  G6Z52_RS01425 (G6Z52_01430) amiE 268385..269455 (+) 1071 WP_002986002.1 ABC transporter ATP-binding protein Regulator
  G6Z52_RS01430 (G6Z52_01435) amiF 269448..270371 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  G6Z52_RS01435 - 270520..270699 (-) 180 WP_100215900.1 transposase -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39749.85 Da        Isoelectric Point: 5.7015

>NTDB_id=425277 G6Z52_RS01425 WP_002986002.1 268385..269455(+) (amiE) [Streptococcus pyogenes strain TSPY1687]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGRQITEVIIKHQKVSNAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=425277 G6Z52_RS01425 WP_002986002.1 268385..269455(+) (amiE) [Streptococcus pyogenes strain TSPY1687]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGACAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTAATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGCCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)

ABC transporter (ABC_tran)

(29-187)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q1JNF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.389

100

0.772
  amiE Streptococcus thermophilus LMG 18311

75.278

100

0.761
  amiE Streptococcus thermophilus LMD-9

75.278

100

0.761
  oppD Streptococcus mutans UA159

56.677

94.663

0.537