Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB2   Type   Machinery gene
Locus tag   HPSH417_RS07560 Genome accession   NC_017739
Coordinates   1589679..1589969 (-) Length   96 a.a.
NCBI ID   WP_000736104.1    Uniprot ID   B3VT60
Organism   Helicobacter pylori Shi417     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1584679..1594969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSH417_RS07535 (HPSH417_07615) - 1585352..1586464 (-) 1113 WP_000067670.1 VirB8/TrbF family protein -
  HPSH417_RS08750 - 1586457..1586591 (-) 135 WP_000738750.1 hypothetical protein -
  HPSH417_RS07545 - 1586593..1589158 (-) 2566 Protein_1467 VirB4 family type IV secretion/conjugal transfer ATPase -
  HPSH417_RS07550 (HPSH417_07630) - 1589158..1589394 (-) 237 WP_000806905.1 hypothetical protein -
  HPSH417_RS07555 (HPSH417_07635) comB3 1589406..1589669 (-) 264 WP_001177721.1 hypothetical protein Machinery gene
  HPSH417_RS07560 (HPSH417_07640) comB2 1589679..1589969 (-) 291 WP_000736104.1 TrbC/VirB2 family protein Machinery gene
  HPSH417_RS07565 (HPSH417_07645) - 1589966..1590445 (-) 480 WP_000571646.1 hypothetical protein -
  HPSH417_RS07570 (HPSH417_07650) - 1590442..1590666 (-) 225 WP_000188955.1 hypothetical protein -
  HPSH417_RS07575 (HPSH417_07655) - 1590669..1591457 (-) 789 WP_001140587.1 hypothetical protein -
  HPSH417_RS07580 (HPSH417_07660) - 1591512..1593416 (+) 1905 Protein_1474 HsdR family type I site-specific deoxyribonuclease -
  HPSH417_RS07585 (HPSH417_07665) - 1593416..1594123 (+) 708 WP_000995212.1 SprT family zinc-dependent metalloprotease -

Sequence

Protein


Download         Length: 96 a.a.        Molecular weight: 10958.29 Da        Isoelectric Point: 11.1589

>NTDB_id=42421 HPSH417_RS07560 WP_000736104.1 1589679..1589969(-) (comB2) [Helicobacter pylori Shi417]
MKKLRHFRKLIAFLGFSPLLLQADMTTFFNSIEQQLQSPTGKGILMIIFIAIGIFVWKNLDRWKEILLTILGVVLGTLIF
FKAPALAQWFMTSVGN

Nucleotide


Download         Length: 291 bp        

>NTDB_id=42421 HPSH417_RS07560 WP_000736104.1 1589679..1589969(-) (comB2) [Helicobacter pylori Shi417]
ATGAAGAAATTAAGACATTTTAGAAAGCTTATCGCCTTTTTAGGTTTTTCACCACTTTTATTACAAGCGGATATGACTAC
ATTTTTTAATAGCATTGAACAACAACTCCAAAGCCCTACAGGTAAGGGCATTTTAATGATTATATTCATTGCTATTGGTA
TTTTTGTGTGGAAAAACTTAGATAGATGGAAAGAAATCTTATTAACTATTTTGGGAGTTGTTTTAGGAACGCTGATATTT
TTTAAAGCCCCAGCCTTAGCTCAATGGTTTATGACTAGTGTTGGTAACTAA

Domains

Predicted by InterProScan.

TrbC/VIRB2 pilin (TrbC)

(4-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B3VT60

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB2 Helicobacter pylori 26695

59.77

90.625

0.542

Multiple sequence alignment