Detailed information NTG0423680

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: G4O42_RS17100
• Genome accession: NZ_CP048876
• Coordinates: 3446157..3447320 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus sp. LUNF1
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3441157..3452320

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
G4O42_RS17070 (G4O42_16950)	-	3441421..3441840 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
G4O42_RS17075 (G4O42_16955)	comFC	3441914..3442603 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
G4O42_RS17080 (G4O42_16960)	-	3442609..3442893 (-)	285	WP_003151389.1	competence protein ComFB	-
G4O42_RS17085 (G4O42_16965)	comFA	3442951..3444336 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
G4O42_RS17090 (G4O42_16970)	-	3444445..3445293 (-)	849	WP_032876160.1	DegV family protein	-
G4O42_RS17095 (G4O42_16975)	degU	3445391..3446080 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
G4O42_RS17100 (G4O42_16980)	degS	3446157..3447320 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
G4O42_RS17105 (G4O42_16985)	-	3447543..3448190 (+)	648	WP_007614107.1	YigZ family protein	-
G4O42_RS17110 (G4O42_16990)	-	3448195..3449376 (+)	1182	WP_032876157.1	LCP family protein	-
G4O42_RS17115 (G4O42_16995)	-	3449475..3450551 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
G4O42_RS17120 (G4O42_17000)	-	3450684..3451880 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=423680 G4O42_RS17100 WP_007407484.1 3446157..3447320(-) (degS) [Bacillus sp. LUNF1]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=423680 G4O42_RS17100 WP_007407484.1 3446157..3447320(-) (degS) [Bacillus sp. LUNF1]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951