Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   LRC_RS05460 Genome accession   NC_015975
Coordinates   1081808..1082632 (-) Length   274 a.a.
NCBI ID   WP_014073505.1    Uniprot ID   G2SNZ2
Organism   Ligilactobacillus ruminis ATCC 27782     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1076808..1087632
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LRC_RS05430 (LRC_10260) - 1077291..1077968 (-) 678 WP_014073501.1 DUF3862 domain-containing protein -
  LRC_RS05435 (LRC_10270) - 1078020..1078571 (-) 552 WP_014073502.1 NUMOD4 domain-containing protein -
  LRC_RS11945 (LRC_10280) - 1078721..1078939 (-) 219 WP_014073503.1 hypothetical protein -
  LRC_RS11950 (LRC_10290) - 1078923..1079303 (-) 381 WP_241531264.1 endo alpha-1,4 polygalactosaminidase -
  LRC_RS05445 (LRC_10300) - 1079426..1080670 (-) 1245 WP_014073504.1 RNA-guided endonuclease TnpB family protein -
  LRC_RS05450 (LRC_10310) - 1080805..1081002 (-) 198 WP_258414218.1 hypothetical protein -
  LRC_RS11955 (LRC_10320) - 1081083..1081606 (-) 524 Protein_1049 nitroreductase family protein -
  LRC_RS12275 - 1081497..1081730 (-) 234 WP_225354871.1 hypothetical protein -
  LRC_RS05460 (LRC_10330) endA 1081808..1082632 (-) 825 WP_014073505.1 DNA/RNA non-specific endonuclease Machinery gene
  LRC_RS10590 (LRC_10340) - 1083105..1083254 (-) 150 WP_080876831.1 methyl-accepting chemotaxis protein -
  LRC_RS05470 (LRC_10350) - 1083524..1086886 (-) 3363 WP_014073506.1 DNA polymerase III subunit alpha -
  LRC_RS05475 (LRC_10360) - 1087050..1087232 (+) 183 WP_014073507.1 YjzD family protein -

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 30486.86 Da        Isoelectric Point: 9.7342

>NTDB_id=42301 LRC_RS05460 WP_014073505.1 1081808..1082632(-) (endA) [Ligilactobacillus ruminis ATCC 27782]
MVKRRKQNKSFATLIIAIGVVLLSWTAFGKKIGLDEWLNSGGQSQTSRVQNDESTPERQLAESVLSDSIRQRLGQKIEWN
GHGAFIINDNKTDLNANVSSAPYAVNRKETGAMIGDAWLNKTTRQYKNRSETGQGRTDWRPQGFKQKLDLSGRYSHAYDR
GHLLAYALVGGLRGFDASESNPDNIATQTAWANEAQSANSTGQNYYEGLVRKALDQNERVRYRVTDLFEEGNLVPSGAHI
EAKSRSGSLEFNVFVPNVQKGIEINYQTGDVSVK

Nucleotide


Download         Length: 825 bp        

>NTDB_id=42301 LRC_RS05460 WP_014073505.1 1081808..1082632(-) (endA) [Ligilactobacillus ruminis ATCC 27782]
ATGGTCAAAAGAAGAAAACAAAACAAAAGCTTTGCGACCCTGATCATTGCCATCGGGGTGGTCCTGCTGAGCTGGACTGC
CTTCGGCAAAAAAATCGGCTTGGACGAGTGGCTGAATTCAGGAGGTCAATCTCAAACAAGCCGCGTCCAAAACGACGAAA
GCACACCGGAAAGACAGCTTGCGGAAAGCGTTTTGAGCGATTCGATCAGACAAAGACTCGGACAGAAAATCGAGTGGAAC
GGACATGGAGCCTTCATCATCAATGATAACAAGACCGATTTGAATGCCAATGTTTCAAGTGCTCCGTATGCGGTCAACAG
AAAAGAAACCGGGGCGATGATTGGGGATGCCTGGCTGAACAAGACGACCAGACAATACAAAAATCGCAGCGAAACCGGCC
AAGGCAGGACCGACTGGCGCCCCCAAGGCTTCAAACAAAAACTTGATTTGAGCGGTCGCTACTCTCATGCTTACGACAGA
GGTCACTTGCTGGCTTATGCTTTGGTCGGGGGACTGAGAGGGTTTGACGCATCTGAATCCAATCCAGACAATATCGCAAC
GCAAACGGCCTGGGCAAATGAGGCCCAAAGCGCAAATTCGACCGGTCAAAACTACTATGAAGGACTTGTCCGAAAAGCGC
TTGATCAAAATGAACGGGTTCGCTATCGCGTTACCGATTTGTTTGAAGAAGGCAATCTGGTTCCTTCCGGGGCGCATATT
GAGGCCAAAAGCAGATCGGGATCGCTTGAATTCAACGTGTTCGTGCCAAACGTTCAAAAGGGCATCGAAATCAATTACCA
AACCGGAGATGTCAGCGTCAAATAA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(119-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G2SNZ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

61.161

81.752

0.5
  endA Streptococcus pneumoniae D39

61.161

81.752

0.5
  endA Streptococcus pneumoniae R6

61.161

81.752

0.5
  endA Streptococcus pneumoniae TIGR4

61.161

81.752

0.5

Multiple sequence alignment