Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   G3G86_RS00285 Genome accession   NZ_CP048713
Coordinates   64094..65719 (-) Length   541 a.a.
NCBI ID   WP_058649872.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain CGMH-SL138     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 38370..65719 64094..65719 within 0


Gene organization within MGE regions


Location: 38370..65719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3G86_RS00175 mecA 38370..40379 (-) 2010 WP_063852638.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  G3G86_RS00180 - 40476..41462 (+) 987 WP_001549960.1 beta-lactam sensor/signal transducer MecR1 -
  G3G86_RS00185 - 41434..41694 (+) 261 WP_001549961.1 type I restriction enzyme endonuclease domain-containing protein -
  G3G86_RS00190 - 41685..43292 (-) 1608 Protein_35 IS1182 family transposase -
  G3G86_RS00195 - 43344..43850 (-) 507 WP_001092189.1 DUF1643 domain-containing protein -
  G3G86_RS00200 - 43865..44176 (-) 312 WP_000700851.1 DUF960 family protein -
  G3G86_RS00205 - 44263..44613 (-) 351 WP_000849672.1 SAUGI family uracil-DNA glycosylase inhibitor -
  G3G86_RS00210 ccrB 45135..46763 (-) 1629 WP_031870018.1 recombinase family protein Machinery gene
  G3G86_RS00215 ccrA 46785..48134 (-) 1350 WP_249689264.1 recombinase family protein Machinery gene
  G3G86_RS00220 - 48368..50155 (-) 1788 WP_249689265.1 DUF927 domain-containing protein -
  G3G86_RS00225 - 50155..50451 (-) 297 WP_002454339.1 single-stranded DNA-binding protein -
  G3G86_RS00230 - 50644..51690 (-) 1047 WP_001042023.1 hypothetical protein -
  G3G86_RS00235 - 52145..53299 (+) 1155 WP_000912116.1 ATP-binding protein -
  G3G86_RS00240 - 53329..54129 (+) 801 WP_058649865.1 abortive infection family protein -
  G3G86_RS00245 - 54285..55426 (+) 1142 WP_094449189.1 IS3 family transposase -
  G3G86_RS00250 - 55869..58898 (-) 3030 WP_058649866.1 type I restriction endonuclease -
  G3G86_RS00255 - 58911..60149 (-) 1239 WP_228279883.1 restriction endonuclease subunit S -
  G3G86_RS00260 - 60142..61929 (-) 1788 WP_058649867.1 class I SAM-dependent DNA methyltransferase -
  G3G86_RS00265 - 62072..62293 (-) 222 WP_058649868.1 hypothetical protein -
  G3G86_RS00270 - 62307..62810 (-) 504 WP_058649869.1 DUF1643 domain-containing protein -
  G3G86_RS00275 - 62825..63136 (-) 312 WP_058649870.1 DUF960 family protein -
  G3G86_RS00280 - 63223..63573 (-) 351 WP_058649871.1 SAUGI family uracil-DNA glycosylase inhibitor -
  G3G86_RS00285 ccrB 64094..65719 (-) 1626 WP_058649872.1 recombinase family protein Machinery gene

Sequence

Protein


Download         Length: 541 a.a.        Molecular weight: 62319.54 Da        Isoelectric Point: 9.7539

>NTDB_id=422489 G3G86_RS00285 WP_058649872.1 64094..65719(-) (ccrB) [Staphylococcus lugdunensis strain CGMH-SL138]
MTQLKKKRIGLYARVSTEMQTDGYSIQGQLNQLKDYCQFQGYEVVNEYTDRGISGKTTQRPELQRMLKDANDGKLDCIMV
YKTNRLARNTSDLLNIVEELYKINVEFFSLTEKIEIASSTGKLMLQILASFSEFERNTIVENVYNGQRQRAIEGYYQGNL
PLGYDKVPDSKKELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDKALWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSIRADVLEKYVMDQILEIIKSKKVLKQLVEKINENSQIDVSSLNHDIAYKQSQCEE
IKAKMHTLTKTIEDSPDLNSVLKPTILSYQDELNQINNQIHQLERDKQAEAPHYDADMIANVLQAIFKDINKLEKSQLKS
LYLTVIDRIDIRKHEHHKKQFYVTLKLNNDIIKQLFDNHPLDEVLLSTSSLFFPQTLYLTI

Nucleotide


Download         Length: 1626 bp        

>NTDB_id=422489 G3G86_RS00285 WP_058649872.1 64094..65719(-) (ccrB) [Staphylococcus lugdunensis strain CGMH-SL138]
ATGACACAACTCAAAAAGAAACGTATTGGATTATATGCCCGTGTATCAACTGAAATGCAAACCGATGGTTACAGTATTCA
AGGTCAATTGAACCAACTCAAAGATTATTGTCAATTTCAAGGCTATGAAGTTGTTAATGAATATACCGATCGTGGTATAT
CTGGTAAAACAACCCAACGCCCTGAACTGCAACGTATGTTAAAAGATGCAAACGACGGTAAGTTAGACTGTATTATGGTC
TACAAAACCAATCGTTTAGCTAGAAATACCTCAGACTTACTAAATATTGTCGAAGAATTGTATAAGATTAATGTCGAATT
TTTTAGTCTCACTGAAAAAATAGAAATTGCCAGCTCAACAGGTAAATTGATGCTCCAAATTCTTGCTAGTTTCTCTGAGT
TTGAAAGAAATACAATCGTAGAAAACGTTTATAACGGTCAAAGACAACGTGCCATTGAAGGTTATTACCAAGGTAATTTA
CCTCTAGGCTATGATAAAGTGCCTGATAGTAAAAAAGAGCTCATGATCAATCAACATGAAGCGAATATTGTTAAATATAT
TTTTGAGTCATACGCCAAAGGTCATGGTTATCGTAAGATTGCGAACGCATTAAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCTTTTAGTATTTCATCCATTACCTACATCATCTCAAACCCTTTTTATATTGGAAAGATACAATTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAAGAACCGATTATTGCAGATGGTAAGCATGCACCTATTATTGA
TAAAGCTTTATGGGATAAAGTACAGTTTAAACGCCAAGAGAGTCGCAAGAAACCACAAGTTCACGGTAAAGGGACCAACC
TACTGACTGGCATTGTAAAATGTCCAAAATGTGGTGCAGCAATGGCCGCAAGTAATACAACCAATACTTTAAAAGATGGC
ACTAAGAAACGAATCAGATATTACTCATGTAGTAATTTTCGTAATAAAGGTTCTAAAGTATGTTCGGCCAATAGCATTAG
AGCAGATGTATTGGAAAAATACGTTATGGATCAAATATTGGAGATTATCAAAAGTAAAAAAGTATTGAAGCAATTGGTTG
AAAAGATAAATGAAAACAGTCAAATAGACGTCTCTTCTTTGAATCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
ATAAAAGCCAAAATGCATACACTAACGAAAACCATTGAAGACTCACCTGACTTAAATAGCGTATTGAAACCAACAATACT
TAGCTACCAAGATGAATTGAATCAAATAAATAATCAAATACATCAACTAGAACGAGATAAACAAGCGGAAGCTCCACATT
ATGATGCTGATATGATTGCCAACGTACTACAAGCTATATTCAAAGACATTAATAAATTAGAGAAATCGCAGTTGAAATCA
CTCTATCTGACGGTTATCGATCGTATTGATATCCGAAAACATGAACATCATAAGAAGCAATTTTATGTTACGCTCAAATT
GAATAACGATATTATTAAACAACTATTTGATAATCATCCACTCGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTTTTC
CCCAAACACTATATCTTACTATTTAG

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Recombinase (Recombinase)

(179-280)

Resolvase, N terminal domain (Resolvase)

(11-154)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.325

100

0.725

Multiple sequence alignment