Detailed information NTG0422009

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: GAU34_RS02245
• Genome accession: NZ_CP048643
• Coordinates: 485799..486686 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain SR153
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 480799..491686

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GAU34_RS02215 (GAU34_02215)	-	481531..482292 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
GAU34_RS02220 (GAU34_02220)	-	482537..482992 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
GAU34_RS15005	-	483114..483215 (+)	102	WP_000731976.1	SE2200 family small protein	-
GAU34_RS02230 (GAU34_02230)	-	483275..484699 (-)	1425	WP_063653204.1	alkaline phosphatase	-
GAU34_RS02235 (GAU34_02235)	-	484897..485097 (+)	201	WP_000604730.1	hypothetical protein	-
GAU34_RS02240 (GAU34_02240)	braR	485123..485788 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
GAU34_RS02245 (GAU34_02245)	braS	485799..486686 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
GAU34_RS02250 (GAU34_02250)	-	486794..487549 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
GAU34_RS02255 (GAU34_02255)	-	487546..489546 (+)	2001	WP_000776751.1	ABC transporter permease	-
GAU34_RS02260 (GAU34_02260)	-	490205..490318 (+)	114	Protein_452	hypothetical protein	-
GAU34_RS02265 (GAU34_02265)	-	490700..490960 (+)	261	WP_001791974.1	hypothetical protein	-
GAU34_RS02270 (GAU34_02270)	-	490970..491467 (+)	498	WP_001065268.1	glutathione peroxidase	-
GAU34_RS02275 (GAU34_02275)	-	491575..491667 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=422009 GAU34_RS02245 WP_000143425.1 485799..486686(+) (braS) [Staphylococcus aureus strain SR153]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=422009 GAU34_RS02245 WP_000143425.1 485799..486686(+) (braS) [Staphylococcus aureus strain SR153]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1