Detailed information NTG0421872

Bioinformatically predicted

Overview

• Name: lqsT
• Type: Regulator
• Locus tag: GCO85_RS12645
• Genome accession: NZ_CP048618
• Coordinates: 2834711..2835973 (+)
• Length: 420 a.a.
• NCBI ID: WP_010948208.1
• Uniprot ID: Q5ZSL1
• Organism: Legionella pneumophila strain ERS1305867
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 2829711..2840973

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GCO85_RS12635 (GCO85_12645)	ceg32	2830585..2833413 (+)	2829	WP_061636134.1	Dot/Icm T4SS effector Ceg32/SidI	-
GCO85_RS12640 (GCO85_12650)	mesI	2833415..2834305 (+)	891	WP_080450413.1	Dot/Icm T4SS effector metaeffector MesI	-
GCO85_RS12645 (GCO85_12655)	lqsT	2834711..2835973 (+)	1263	WP_010948208.1	HAMP domain-containing sensor histidine kinase	Regulator
GCO85_RS12650 (GCO85_12660)	-	2836021..2836716 (-)	696	WP_061636132.1	iron-containing redox enzyme family protein	-
GCO85_RS12655 (GCO85_12665)	sdjA	2837113..2839536 (-)	2424	WP_061636131.1	Dot/Icm T4SS effector SdjA	-
GCO85_RS12660 (GCO85_12670)	dupB	2839608..2840801 (-)	1194	WP_072356452.1	Dot/Icm T4SS effector deubiquitinase DupB/LaiF	-

Sequence

Protein

• Length: 420 a.a.
• Molecular weight: 48657.07 Da
• Isoelectric Point: 7.9744

>NTDB_id=421872 GCO85_RS12645 WP_010948208.1 2834711..2835973(+) (lqsT) [Legionella pneumophila strain ERS1305867]
MQRLKNIFTAIYQYLLKETEDASHQITLFGIVMMINYPLFGVFWKLEHFQLTEEFILRITAALLCACLAFNQFWPRQLLK
FLPVFWYIVLLFCLPYFFAYLTLINNGSTLWLMNCVSAIFFLLLVSSVLGALILLISGVGLAFFHFYILSNNQFVYIPGT
ISLFSLIVTFIAAIIIGALFARDREITYAGRLSGMRMLAGSIAHDLRTPLASIYLQAELQELIVERLNNPEVQKDLKENL
SKITRGIEMSNQLIRMQLNNIQRDKLDTSTFSIYSIKKLLKASLEEYPFKENQKSLIHLNDKNDFSIWIDEVGFKNMMWN
LLKNSLEYIEETHKGEISIWLEQGWEKENFNYLHIKDTAKGLNHKEYEKIFDFFYSGRKEGTGLGLAYCKLLMQAAGGDI
SCKGKKNEFAHFTLKFPKID

Nucleotide

• Length: 1263 bp

>NTDB_id=421872 GCO85_RS12645 WP_010948208.1 2834711..2835973(+) (lqsT) [Legionella pneumophila strain ERS1305867]
ATGCAAAGGTTAAAAAATATATTTACTGCAATTTACCAATATTTATTAAAAGAAACTGAAGATGCAAGCCACCAAATCAC
TTTATTTGGCATCGTCATGATGATTAATTACCCTCTTTTCGGAGTTTTCTGGAAACTGGAGCATTTTCAACTGACAGAAG
AATTTATTTTACGCATCACTGCAGCCCTCCTCTGTGCCTGTTTGGCATTTAATCAATTTTGGCCAAGACAATTATTAAAA
TTTTTACCTGTTTTTTGGTATATAGTTCTTCTCTTTTGTTTACCTTACTTTTTTGCTTATTTGACTCTCATAAACAATGG
CTCGACTCTTTGGCTAATGAATTGCGTATCCGCTATCTTTTTTCTTTTATTAGTTTCCAGTGTATTGGGGGCTCTTATAT
TACTTATATCAGGTGTTGGACTTGCTTTTTTTCATTTTTATATTTTATCAAATAATCAGTTTGTCTATATCCCAGGAACC
ATATCACTTTTTAGTTTAATTGTTACGTTTATTGCAGCAATAATCATTGGCGCCTTGTTTGCACGAGATAGAGAAATTAC
CTATGCCGGACGTTTATCGGGTATGCGCATGCTGGCTGGAAGTATCGCTCATGATTTAAGAACGCCGCTTGCCAGTATTT
ATTTACAAGCCGAATTACAGGAATTGATTGTTGAAAGATTAAATAATCCAGAAGTTCAAAAGGACCTGAAGGAAAATTTA
AGCAAAATTACTCGCGGCATAGAAATGAGTAATCAACTAATTCGTATGCAATTAAATAATATTCAACGAGACAAATTAGA
TACCAGTACATTTTCGATTTATTCCATCAAAAAATTGCTCAAAGCGTCTTTAGAAGAATACCCTTTCAAAGAAAATCAAA
AATCATTGATTCATTTAAATGATAAAAATGATTTTTCCATATGGATTGATGAAGTGGGTTTTAAAAATATGATGTGGAAT
TTGCTAAAAAATAGCCTGGAATATATTGAGGAAACCCATAAAGGCGAAATCTCTATCTGGCTAGAACAAGGATGGGAGAA
AGAGAATTTTAATTACCTCCATATAAAAGATACAGCTAAAGGTTTAAATCATAAAGAATATGAAAAAATATTTGATTTCT
TCTATTCTGGCAGAAAAGAAGGAACTGGTTTAGGCTTGGCCTATTGTAAACTTCTGATGCAAGCAGCTGGTGGTGATATT
TCCTGTAAAGGGAAAAAAAATGAATTCGCTCATTTCACTTTAAAATTCCCCAAAATTGATTAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (310-417)

• His Kinase A (phospho-acceptor) domain (HisKA) (198-255)

3D structure

• AlphaFold DB: Q5ZSL1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
lqsT	Legionella pneumophila subsp. pneumophila str. Philadelphia 1	100	100	1