Detailed information
Bioinformatically predicted
Overview
| Name | rocC | Type | Regulator |
| Locus tag | GCO85_RS00750 | Genome accession | NZ_CP048618 |
| Coordinates | 166607..167299 (+) | Length | 230 a.a. |
| NCBI ID | WP_011212783.1 | Uniprot ID | - |
| Organism | Legionella pneumophila strain ERS1305867 | ||
| Function | rocR chaperone; repress natural transformation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 141080..203726 | 166607..167299 | within | 0 |
Gene organization within MGE regions
Location: 141080..203726
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| GCO85_RS00645 (GCO85_00645) | - | 141505..142749 (-) | 1245 | WP_061636572.1 | HDOD domain-containing protein | - |
| GCO85_RS00650 (GCO85_00650) | gcvPB | 142954..144408 (-) | 1455 | WP_027225338.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPB | - |
| GCO85_RS00655 (GCO85_00655) | - | 144411..144710 (-) | 300 | WP_014840766.1 | YciI family protein | - |
| GCO85_RS00660 (GCO85_00660) | gcvPA | 144710..146080 (-) | 1371 | WP_061636571.1 | aminomethyl-transferring glycine dehydrogenase subunit GcvPA | - |
| GCO85_RS00665 (GCO85_00665) | gcvH | 146083..146460 (-) | 378 | WP_010945878.1 | glycine cleavage system protein GcvH | - |
| GCO85_RS00670 (GCO85_00670) | gcvT | 146494..147576 (-) | 1083 | WP_011212769.1 | glycine cleavage system aminomethyltransferase GcvT | - |
| GCO85_RS00675 (GCO85_00675) | - | 147711..148178 (+) | 468 | WP_011945317.1 | DUF3592 domain-containing protein | - |
| GCO85_RS00680 (GCO85_00680) | - | 148153..148683 (-) | 531 | WP_042754837.1 | DotI/IcmL family type IV secretion protein | - |
| GCO85_RS00685 (GCO85_00685) | - | 149182..150921 (+) | 1740 | WP_080450487.1 | ABC transporter permease subunit | - |
| GCO85_RS00690 (GCO85_00690) | - | 150929..152227 (+) | 1299 | WP_010945883.1 | nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein | - |
| GCO85_RS00695 (GCO85_00695) | - | 152387..153001 (-) | 615 | WP_011212772.1 | thiol:disulfide interchange protein DsbA/DsbL | - |
| GCO85_RS00700 (GCO85_00700) | - | 153012..153614 (-) | 603 | WP_061636570.1 | c-type cytochrome | - |
| GCO85_RS00705 (GCO85_00705) | yihA | 153689..154291 (+) | 603 | WP_027225341.1 | ribosome biogenesis GTP-binding protein YihA/YsxC | - |
| GCO85_RS00710 (GCO85_00710) | cegC2 | 154405..157716 (+) | 3312 | WP_061636569.1 | Dot/Icm T4SS effector CegC2 | - |
| GCO85_RS00715 (GCO85_00715) | acs | 157813..159696 (-) | 1884 | WP_061636568.1 | acetate--CoA ligase | - |
| GCO85_RS00720 (GCO85_00720) | mmsB | 159698..160594 (-) | 897 | WP_061636567.1 | 3-hydroxyisobutyrate dehydrogenase | - |
| GCO85_RS00725 (GCO85_00725) | - | 160618..162117 (-) | 1500 | WP_027225345.1 | CoA-acylating methylmalonate-semialdehyde dehydrogenase | - |
| GCO85_RS00730 (GCO85_00730) | - | 162228..162404 (-) | 177 | WP_014840774.1 | dodecin domain-containing protein | - |
| GCO85_RS00735 (GCO85_00735) | - | 162582..165050 (+) | 2469 | WP_011212780.1 | hypothetical protein | - |
| GCO85_RS00740 (GCO85_00740) | dapB | 165154..165885 (-) | 732 | WP_011212781.1 | 4-hydroxy-tetrahydrodipicolinate reductase | - |
| GCO85_RS00745 (GCO85_00745) | - | 166065..166250 (-) | 186 | WP_011212782.1 | hypothetical protein | - |
| GCO85_RS00750 (GCO85_00750) | rocC | 166607..167299 (+) | 693 | WP_011212783.1 | ProQ/FinO family protein | Regulator |
| GCO85_RS00755 (GCO85_00755) | - | 167300..168370 (+) | 1071 | WP_011212784.1 | hypothetical protein | - |
| GCO85_RS00760 (GCO85_00760) | - | 168470..174097 (-) | 5628 | WP_080450485.1 | SdhB | - |
| GCO85_RS00765 (GCO85_00765) | pyk | 174189..175613 (-) | 1425 | WP_061636565.1 | pyruvate kinase | - |
| GCO85_RS00770 (GCO85_00770) | - | 175597..176787 (-) | 1191 | WP_027268220.1 | phosphoglycerate kinase | - |
| GCO85_RS00775 (GCO85_00775) | gap | 176798..177790 (-) | 993 | WP_061636564.1 | type I glyceraldehyde-3-phosphate dehydrogenase | - |
| GCO85_RS00780 (GCO85_00780) | tkt | 177871..179949 (-) | 2079 | WP_080450484.1 | transketolase | - |
| GCO85_RS00785 (GCO85_00785) | - | 180135..181469 (+) | 1335 | WP_061401246.1 | hypothetical protein | - |
| GCO85_RS00790 (GCO85_00790) | - | 181569..183584 (+) | 2016 | WP_061401245.1 | M3 family metallopeptidase | - |
| GCO85_RS00800 (GCO85_00800) | - | 184528..185721 (-) | 1194 | WP_061636562.1 | site-specific integrase | - |
| GCO85_RS00805 (GCO85_00805) | - | 185670..185876 (-) | 207 | WP_080450483.1 | excisionase | - |
| GCO85_RS00810 (GCO85_00810) | - | 185883..186164 (-) | 282 | WP_061636561.1 | hypothetical protein | - |
| GCO85_RS00815 (GCO85_00815) | - | 186408..187049 (+) | 642 | WP_061636608.1 | LexA family transcriptional regulator | - |
| GCO85_RS00820 (GCO85_00820) | - | 187024..187779 (-) | 756 | WP_061636560.1 | queuosine precursor transporter | - |
| GCO85_RS00825 (GCO85_00825) | - | 187798..188292 (-) | 495 | WP_061636559.1 | hypothetical protein | - |
| GCO85_RS00830 (GCO85_00830) | - | 188303..189526 (-) | 1224 | WP_061636558.1 | methyltransferase | - |
| GCO85_RS00835 (GCO85_00835) | - | 189620..190339 (-) | 720 | WP_061636557.1 | hypothetical protein | - |
| GCO85_RS00840 (GCO85_00840) | - | 190336..190998 (-) | 663 | WP_061636556.1 | hypothetical protein | - |
| GCO85_RS00845 (GCO85_00845) | - | 191075..191332 (-) | 258 | WP_061636555.1 | conjugal transfer protein TraD | - |
| GCO85_RS00850 (GCO85_00850) | - | 191319..191525 (-) | 207 | WP_061636554.1 | hypothetical protein | - |
| GCO85_RS00855 (GCO85_00855) | traA | 191773..194793 (+) | 3021 | WP_061636553.1 | Ti-type conjugative transfer relaxase TraA | - |
| GCO85_RS00860 (GCO85_00860) | - | 194687..195754 (-) | 1068 | WP_061636552.1 | hypothetical protein | - |
| GCO85_RS00865 (GCO85_00865) | - | 195755..197656 (-) | 1902 | WP_061636551.1 | type IV secretory system conjugative DNA transfer family protein | - |
| GCO85_RS00870 (GCO85_00870) | virB11 | 197649..198653 (-) | 1005 | WP_061636550.1 | P-type DNA transfer ATPase VirB11 | - |
| GCO85_RS00875 (GCO85_00875) | - | 198655..199746 (-) | 1092 | WP_061636549.1 | TrbI/VirB10 family protein | - |
| GCO85_RS00880 (GCO85_00880) | virB9 | 199743..200495 (-) | 753 | WP_061636548.1 | P-type conjugative transfer protein VirB9 | - |
| GCO85_RS00885 (GCO85_00885) | - | 200492..201208 (-) | 717 | WP_061636547.1 | type IV secretion system protein | - |
| GCO85_RS00890 (GCO85_00890) | - | 201205..202245 (-) | 1041 | WP_061636546.1 | type IV secretion system protein | - |
| GCO85_RS00895 (GCO85_00895) | lvrD | 202248..202643 (-) | 396 | WP_061636545.1 | T4SS-associated protein LvrD | - |
| GCO85_RS15955 | lvhB7 | 202640..202786 (-) | 147 | WP_080450481.1 | T4SS-associated protein LvhB7 | - |
| GCO85_RS00900 (GCO85_00900) | - | 202801..203511 (-) | 711 | WP_061636544.1 | type IV secretion system protein | - |
Sequence
Protein
Download Length: 230 a.a. Molecular weight: 25773.65 Da Isoelectric Point: 10.6563
>NTDB_id=421858 GCO85_RS00750 WP_011212783.1 166607..167299(+) (rocC) [Legionella pneumophila strain ERS1305867]
MRKQALHPRTAVINKAQKNQSKRARSDALLWLAANFPEAFDNSLRIRPLKIGIMSDILQHAEKAEQVGVSKSKLREAVVL
FTRRLDYLACLKAREVRIDLHGNPVAEVTEEEAENASMKIKKRVEKSVKNARKQVNAKAANHSYVNNQPSTVSSVKPMNS
FDSHPEPLLPIYPLRSSTYASQNVAMQSAKSPSVVVKHKAPKQYDPDAVARLKEKLGLSRKAEDKKETTE
MRKQALHPRTAVINKAQKNQSKRARSDALLWLAANFPEAFDNSLRIRPLKIGIMSDILQHAEKAEQVGVSKSKLREAVVL
FTRRLDYLACLKAREVRIDLHGNPVAEVTEEEAENASMKIKKRVEKSVKNARKQVNAKAANHSYVNNQPSTVSSVKPMNS
FDSHPEPLLPIYPLRSSTYASQNVAMQSAKSPSVVVKHKAPKQYDPDAVARLKEKLGLSRKAEDKKETTE
Nucleotide
Download Length: 693 bp
>NTDB_id=421858 GCO85_RS00750 WP_011212783.1 166607..167299(+) (rocC) [Legionella pneumophila strain ERS1305867]
ATGAGAAAGCAGGCGCTGCACCCACGAACCGCTGTCATCAATAAAGCACAAAAAAATCAATCCAAGCGCGCGCGATCTGA
CGCATTATTATGGCTTGCGGCTAATTTCCCTGAGGCATTCGATAATTCTTTGCGTATTCGGCCATTAAAGATTGGTATTA
TGTCTGATATATTGCAGCATGCAGAAAAAGCAGAGCAAGTTGGAGTTTCTAAAAGCAAATTAAGGGAAGCTGTTGTTCTT
TTTACCCGTCGTCTTGATTATCTGGCTTGCCTGAAAGCTCGTGAAGTCCGTATCGATTTGCACGGAAATCCAGTAGCGGA
GGTTACTGAGGAAGAAGCGGAGAATGCTTCCATGAAAATTAAAAAACGCGTGGAAAAGAGTGTTAAAAATGCTCGCAAAC
AAGTGAATGCAAAAGCGGCTAATCATTCATATGTAAATAATCAGCCAAGTACAGTTTCCAGCGTTAAGCCAATGAATTCG
TTTGACTCTCATCCTGAGCCTCTTTTGCCAATATATCCTCTCAGAAGCTCTACCTATGCCTCACAAAATGTGGCAATGCA
ATCCGCCAAGTCACCATCCGTAGTAGTCAAACATAAAGCACCAAAGCAATATGATCCGGATGCTGTAGCTCGTTTAAAAG
AAAAATTAGGATTGTCTCGAAAAGCAGAAGATAAAAAGGAAACAACAGAGTAA
ATGAGAAAGCAGGCGCTGCACCCACGAACCGCTGTCATCAATAAAGCACAAAAAAATCAATCCAAGCGCGCGCGATCTGA
CGCATTATTATGGCTTGCGGCTAATTTCCCTGAGGCATTCGATAATTCTTTGCGTATTCGGCCATTAAAGATTGGTATTA
TGTCTGATATATTGCAGCATGCAGAAAAAGCAGAGCAAGTTGGAGTTTCTAAAAGCAAATTAAGGGAAGCTGTTGTTCTT
TTTACCCGTCGTCTTGATTATCTGGCTTGCCTGAAAGCTCGTGAAGTCCGTATCGATTTGCACGGAAATCCAGTAGCGGA
GGTTACTGAGGAAGAAGCGGAGAATGCTTCCATGAAAATTAAAAAACGCGTGGAAAAGAGTGTTAAAAATGCTCGCAAAC
AAGTGAATGCAAAAGCGGCTAATCATTCATATGTAAATAATCAGCCAAGTACAGTTTCCAGCGTTAAGCCAATGAATTCG
TTTGACTCTCATCCTGAGCCTCTTTTGCCAATATATCCTCTCAGAAGCTCTACCTATGCCTCACAAAATGTGGCAATGCA
ATCCGCCAAGTCACCATCCGTAGTAGTCAAACATAAAGCACCAAAGCAATATGATCCGGATGCTGTAGCTCGTTTAAAAG
AAAAATTAGGATTGTCTCGAAAAGCAGAAGATAAAAAGGAAACAACAGAGTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| rocC | Legionella pneumophila str. Paris |
100 |
100 |
1 |