Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   G3M67_RS02590 Genome accession   NZ_CP048601
Coordinates   560945..562729 (-) Length   594 a.a.
NCBI ID   WP_163524471.1    Uniprot ID   -
Organism   Helicobacter pylori strain GCT 27     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 555945..567729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M67_RS02560 (G3M67_02560) - 556326..556574 (+) 249 WP_000790551.1 RNA-binding protein -
  G3M67_RS02565 (G3M67_02565) - 556784..557605 (-) 822 WP_163524470.1 glycosyltransferase family 25 protein -
  G3M67_RS02570 (G3M67_02570) trxB 557975..558910 (-) 936 WP_001881291.1 thioredoxin-disulfide reductase -
  G3M67_RS02575 (G3M67_02575) trxA 558916..559236 (-) 321 WP_000020192.1 thioredoxin -
  G3M67_RS02580 (G3M67_02580) - 559325..559669 (-) 345 WP_001211712.1 YraN family protein -
  G3M67_RS02585 (G3M67_02585) - 559670..560935 (-) 1266 WP_000746754.1 homoserine dehydrogenase -
  G3M67_RS02590 (G3M67_02590) uvrC 560945..562729 (-) 1785 WP_163524471.1 excinuclease ABC subunit UvrC Machinery gene
  G3M67_RS02595 (G3M67_02595) - 562730..563191 (-) 462 WP_000437154.1 hypothetical protein -
  G3M67_RS02600 (G3M67_02600) - 563183..563362 (+) 180 WP_000468798.1 hypothetical protein -
  G3M67_RS02605 (G3M67_02605) - 563365..564015 (-) 651 WP_163524472.1 ATP-binding cassette domain-containing protein -
  G3M67_RS02610 (G3M67_02610) - 564018..565680 (-) 1663 Protein_532 glycine betaine ABC transporter substrate-binding protein -
  G3M67_RS02615 (G3M67_02615) - 565796..566233 (-) 438 WP_000802458.1 hypothetical protein -
  G3M67_RS02620 (G3M67_02620) motB 566239..567012 (-) 774 WP_163524473.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68618.75 Da        Isoelectric Point: 9.5365

>NTDB_id=421708 G3M67_RS02590 WP_163524471.1 560945..562729(-) (uvrC) [Helicobacter pylori strain GCT 27]
MADLLSGLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSVRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMECLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
DCSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDLILEEVRSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRN

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=421708 G3M67_RS02590 WP_163524471.1 560945..562729(-) (uvrC) [Helicobacter pylori strain GCT 27]
ATGGCTGATTTATTGTCCGGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCTGTCCGTAATAATGAAATCACGCCCA
ACCCTCGCGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCCAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCCATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTAGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGTGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGAGATAGGATTGCAAAAATCCAAAAAATC
GCCCCCTTCACTTGCATGGATTTAGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGTGGGAACAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAGCAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTGATGCCTGAACAGATCTTATTGAGC
GATTGCTCTAATGAGGTGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAGGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCTGATTTTAGAAGAAGTGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTTCAAAAAAACTCTTATCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACCAGAAGGGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTGATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAATTAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

95.953

99.832

0.958

Multiple sequence alignment