Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   G3M68_RS03565 Genome accession   NZ_CP048600
Coordinates   763368..765152 (-) Length   594 a.a.
NCBI ID   WP_163497942.1    Uniprot ID   -
Organism   Helicobacter pylori strain GCT 43     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 758368..770152
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M68_RS03545 (G3M68_03545) trxB 760397..761332 (-) 936 WP_163497940.1 thioredoxin-disulfide reductase -
  G3M68_RS03550 (G3M68_03550) trxA 761338..761658 (-) 321 WP_000020189.1 thioredoxin -
  G3M68_RS03555 (G3M68_03555) - 761747..762091 (-) 345 WP_077648390.1 YraN family protein -
  G3M68_RS03560 (G3M68_03560) - 762092..763357 (-) 1266 WP_163497941.1 homoserine dehydrogenase -
  G3M68_RS03565 (G3M68_03565) uvrC 763368..765152 (-) 1785 WP_163497942.1 excinuclease ABC subunit UvrC Machinery gene
  G3M68_RS03570 (G3M68_03570) - 765153..765614 (-) 462 WP_000437155.1 hypothetical protein -
  G3M68_RS03575 (G3M68_03575) - 765606..765785 (+) 180 WP_001884321.1 hypothetical protein -
  G3M68_RS03580 (G3M68_03580) - 765788..766438 (-) 651 WP_097703055.1 ATP-binding cassette domain-containing protein -
  G3M68_RS03585 (G3M68_03585) - 766441..768102 (-) 1662 WP_163497943.1 glycine betaine ABC transporter substrate-binding protein -
  G3M68_RS03590 (G3M68_03590) - 768171..768608 (-) 438 WP_163497944.1 hypothetical protein -
  G3M68_RS03595 (G3M68_03595) motB 768614..769387 (-) 774 WP_120820822.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68661.79 Da        Isoelectric Point: 9.7157

>NTDB_id=421693 G3M68_RS03565 WP_163497942.1 763368..765152(-) (uvrC) [Helicobacter pylori strain GCT 43]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRVQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACIFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGASNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNETLKELQEFISHQYSKKIALSIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKDSYRRYHLKGSNEYDQMSELLTRRALDFTKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTISNTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLRKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=421693 G3M68_RS03565 WP_163497942.1 763368..765152(-) (uvrC) [Helicobacter pylori strain GCT 43]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAACTTAAAAAAGCGCATCAAAAGCTATTTTTCTATCCGTAATAATGAAATCACGCCCA
ACCCTCGTGCAAGTTTACGCGTCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTGATCAAGCAGCTCAAGCCTAAATACAACATTCTTTTAAGAGACGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCCATCCCTTTAATCACACGAAAAATCTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTCACGAGCGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCTTTGGTTCAAAAGAAA
AATTGCATCAAGGATAAAAAGGCATGCATATTTTATCAAATAGAGCGTTGTAAAGCCCCATGCGAGGATAAAATCACTAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTAATTTACAGGGACAGAATTGCAAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTGGCCAAACTCTACGATTTGGATATTTTTGCTTTTTATGGCGCAAGCAATAAGGCGGT
GTTAGTGAAAATGTTTATGCGTGGGGGTAAAATCATTTCTTCTGCGTTTGAAAAAATCCACTCCCTCAATGGGTTTGACA
CTGATGAAGCGATGAAGCAAGCCATTATCAACCATTACCAATCGCATTTGCCTTTGATGCCTGAACAAATCTTATTGAGC
GCTTGTTCTAATGAAACGCTTAAAGAATTGCAAGAGTTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAGCATTCC
TAAAAAAGGCGATAAGCTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTCTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGACACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCCTTTCAAAAAGACTCTTATCGGCG
TTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACTAGAAGAGCCTTAGACTTTACTAAAGAGC
CACCGCCTAATTTGTGGGTGATTGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGTTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGATTAGTAATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAATGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTATTAGATTATTTTGGAAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAGAAAACGAAAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)

UvrB/uvrC motif (UVR)

(205-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

96.965

99.832

0.968

Multiple sequence alignment