Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB4   Type   Machinery gene
Locus tag   G3M68_RS03500 Genome accession   NZ_CP048600
Coordinates   748416..750779 (-) Length   787 a.a.
NCBI ID   WP_163497935.1    Uniprot ID   -
Organism   Helicobacter pylori strain GCT 43     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 743416..755779
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M68_RS03475 (G3M68_03475) lpxE 743896..744429 (+) 534 WP_230078085.1 lipid A 1-phosphatase LpxE -
  G3M68_RS03480 (G3M68_03480) nspC 744480..745697 (-) 1218 WP_097702450.1 carboxynorspermidine decarboxylase -
  G3M68_RS03485 (G3M68_03485) cheV1 745694..746659 (-) 966 WP_000785454.1 chemotaxis protein CheV1 -
  G3M68_RS03490 (G3M68_03490) - 746761..748101 (-) 1341 WP_001876830.1 COG3014 family protein -
  G3M68_RS03500 (G3M68_03500) comB4 748416..750779 (-) 2364 WP_163497935.1 VirB4 family type IV secretion/conjugal transfer ATPase Machinery gene
  G3M68_RS03505 (G3M68_03505) comB3 750781..751044 (-) 264 WP_000584973.1 hypothetical protein Machinery gene
  G3M68_RS03510 (G3M68_03510) comB2 751044..751325 (-) 282 WP_001272690.1 TrbC/VirB2 family protein Machinery gene
  G3M68_RS03515 (G3M68_03515) - 751470..752297 (-) 828 WP_163497936.1 DUF5718 family protein -
  G3M68_RS03520 (G3M68_03520) - 752389..753441 (-) 1053 WP_163497937.1 MnmA/TRMU family protein -
  G3M68_RS03525 (G3M68_03525) dnaG 753438..755117 (-) 1680 WP_163497938.1 DNA primase -
  G3M68_RS03530 (G3M68_03530) groES 755403..755759 (+) 357 WP_000671931.1 co-chaperone GroES -

Sequence

Protein


Download         Length: 787 a.a.        Molecular weight: 90188.72 Da        Isoelectric Point: 8.8662

>NTDB_id=421690 G3M68_RS03500 WP_163497935.1 748416..750779(-) (comB4) [Helicobacter pylori strain GCT 43]
MLEKLLGAIKQKVSNYFLGVLPKSYSMSEENNILGLYDEHFLLTKNENLVGILRLEGVSYTHLSTEQLQDLFTERQMALD
SLEKVVARLVVKRRKIDYKQNIQADSKYLQAILNQFENKEVYENQYFLVLESTHSLQGVLEHKKKSFMHANRENFKDILS
YKAHFLQETLKSLEIQLKNYAPKLLSSKEVLNFYAEYINGFDLPLKPLVGGYLSDSYIASSITFEKDYFIQESFNQKTYN
RLIGIKAYESERITSIAVGALLYQETPLDIIFSIEPMSAHKTLSFLKERAKFSMSNLVKNELLEYQELVKTKRLSMQKFA
LNVLIKAPSLEDLDAQTSLILGLLFKENLVGVIETFGLKGGYFSFFPERIHLNHRLRFLTSKALACLMVFERQNLGFKAN
SWGNSPLSVFKNLDYSPFLFNFHNQEVSHNNAKEIARVNGHTLIIGATGSGKSTLISFLMMSALKYQNMRLLAFDRMQGL
YSFTKFFKGHYHDGQSFSINPFCLEPNLQNLEFLQSFFLSMFDLTPSRDKEALEDMNAISGAIKSLYETLYPKAFSLLDF
KETLKRTSSNQLSLSLEPYLNNPLFNALNDAFNSNAFLNVINLDAITQNPKDLGLLAYYLFYKILEESRKNDSGFLVFLD
EFKSYVENDLLNTKINALITQARKANGVVVLALQDIYQLSGVKNAHSFLSNMGTLILYPQKNARELKHNFNVPLSETEIS
FLENTPLYARQVLVKNLGNGSSNMIDVSLEGLGRYLKIFNSDSSHVNKVKALQKDYPTEWREKLLKS

Nucleotide


Download         Length: 2364 bp        

>NTDB_id=421690 G3M68_RS03500 WP_163497935.1 748416..750779(-) (comB4) [Helicobacter pylori strain GCT 43]
ATGTTAGAAAAGCTTTTAGGCGCTATCAAACAAAAGGTTTCAAACTATTTTTTGGGGGTTTTGCCTAAAAGCTATTCAAT
GAGTGAAGAAAACAACATTTTAGGCTTGTATGATGAGCATTTTTTACTCACTAAAAACGAAAACTTAGTGGGCATCCTCC
GTTTAGAGGGGGTTAGTTACACCCATTTAAGCACAGAGCAATTGCAAGATCTTTTCACAGAGCGCCAAATGGCGTTGGAT
TCTTTAGAAAAGGTCGTGGCACGCCTTGTGGTTAAAAGGCGTAAAATTGATTATAAACAAAACATTCAAGCTGACTCTAA
ATATTTGCAAGCGATTTTGAATCAATTTGAAAATAAAGAAGTGTATGAAAATCAGTATTTTTTAGTTTTAGAAAGCACTC
ACTCTTTACAAGGTGTTTTGGAGCATAAGAAAAAATCTTTCATGCACGCTAATAGGGAAAATTTTAAGGACATTCTCTCT
TATAAAGCGCATTTTTTGCAAGAAACTTTAAAAAGCCTAGAAATCCAACTCAAAAATTATGCCCCCAAACTCTTAAGCTC
TAAAGAGGTTTTGAATTTTTATGCAGAATACATTAATGGGTTTGATCTCCCCCTAAAACCCCTAGTAGGGGGGTATTTGA
GCGATAGTTATATCGCTAGCTCTATCACTTTTGAAAAAGATTATTTCATTCAAGAAAGCTTTAACCAAAAAACCTATAAC
CGCTTGATTGGCATTAAAGCTTATGAGAGCGAACGCATCACTTCTATAGCGGTGGGAGCGCTTTTATACCAAGAGACGCC
ACTAGATATTATCTTTTCTATAGAGCCTATGAGCGCGCATAAAACGCTGAGTTTTTTAAAAGAGAGGGCCAAGTTTAGCA
TGTCCAATCTCGTTAAAAACGAGCTGCTAGAATACCAAGAATTAGTCAAAACCAAACGCTTATCCATGCAAAAATTCGCC
CTAAACGTTCTTATCAAAGCCCCCAGTTTAGAGGATTTAGACGCTCAAACGAGCTTAATTTTAGGGCTTTTATTTAAAGA
AAACTTAGTGGGCGTTATAGAAACTTTTGGCTTGAAAGGGGGGTATTTTTCCTTTTTCCCTGAACGCATCCACTTAAACC
ACCGCTTGCGTTTTTTAACCTCTAAAGCCCTAGCGTGTTTGATGGTGTTTGAAAGGCAAAATTTAGGCTTTAAGGCTAAT
TCATGGGGGAATAGCCCTTTGAGCGTGTTTAAAAATTTGGATTATTCCCCTTTTTTATTCAATTTCCACAACCAAGAAGT
GAGCCACAATAACGCTAAAGAAATCGCCAGAGTGAATGGGCATACTCTAATCATAGGGGCTACCGGAAGCGGTAAAAGCA
CGCTGATTAGCTTTTTAATGATGAGCGCTTTGAAATACCAAAACATGCGCCTTTTAGCCTTTGACAGGATGCAAGGGCTA
TATTCTTTCACAAAATTTTTTAAAGGGCATTACCATGACGGCCAATCTTTTAGCATCAACCCCTTTTGTTTAGAGCCTAA
TTTACAGAATCTAGAATTTTTGCAATCCTTTTTTTTGAGCATGTTTGATCTTACCCCTTCAAGAGATAAAGAAGCCTTAG
AAGACATGAATGCGATTTCTGGCGCGATTAAGAGCCTTTATGAGACCTTATACCCTAAAGCCTTTAGTTTGCTAGACTTT
AAAGAAACGCTTAAAAGAACCTCATCTAACCAACTAAGCTTGAGCTTGGAGCCGTATTTGAATAACCCTCTTTTTAACGC
TTTGAATGACGCGTTCAACTCCAACGCTTTTTTAAACGTGATAAACCTAGACGCGATCACCCAAAACCCTAAAGACTTAG
GGCTTTTAGCCTATTACTTGTTTTATAAAATCTTAGAAGAATCCAGGAAAAACGACAGCGGTTTTTTGGTTTTTTTAGAC
GAGTTTAAATCCTATGTGGAAAACGATTTATTGAACACTAAAATTAACGCTTTAATCACGCAAGCCAGAAAAGCTAATGG
CGTGGTGGTGTTGGCCTTGCAAGATATTTACCAATTAAGCGGGGTTAAAAACGCTCATAGTTTTTTAAGCAACATGGGGA
CTCTCATTTTGTATCCGCAAAAAAACGCTAGGGAGTTGAAACACAACTTCAATGTGCCTTTGAGCGAAACTGAAATTTCT
TTTTTAGAAAACACCCCTTTGTATGCCAGGCAGGTTTTAGTCAAAAATCTGGGTAATGGGAGCTCTAACATGATTGATGT
GAGTTTGGAGGGCTTGGGGCGTTATTTGAAAATCTTTAATTCAGATTCTAGTCATGTCAATAAAGTGAAAGCGTTACAAA
AAGACTACCCTACAGAGTGGCGTGAGAAACTTTTGAAGAGTTAG

Domains

Predicted by InterproScan.

CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB)

(176-375)

FtsK/SpoIIIE family (FtsK_SpoIIIE)

(426-466)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB4 Helicobacter pylori 26695

97.459

100

0.975

Multiple sequence alignment