Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   G3M69_RS02680 Genome accession   NZ_CP048599
Coordinates   575370..577154 (-) Length   594 a.a.
NCBI ID   WP_163562937.1    Uniprot ID   -
Organism   Helicobacter pylori strain GCT 97     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 570370..582154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  G3M69_RS02650 (G3M69_02650) - 570726..570974 (+) 249 WP_077366900.1 RNA-binding protein -
  G3M69_RS02655 (G3M69_02655) - 571193..572014 (-) 822 WP_163562935.1 glycosyltransferase family 25 protein -
  G3M69_RS02660 (G3M69_02660) trxB 572397..573332 (-) 936 WP_000564379.1 thioredoxin-disulfide reductase -
  G3M69_RS02665 (G3M69_02665) trxA 573338..573658 (-) 321 WP_000020199.1 thioredoxin -
  G3M69_RS02670 (G3M69_02670) - 573750..574094 (-) 345 WP_001211718.1 YraN family protein -
  G3M69_RS02675 (G3M69_02675) - 574095..575360 (-) 1266 WP_163562936.1 homoserine dehydrogenase -
  G3M69_RS02680 (G3M69_02680) uvrC 575370..577154 (-) 1785 WP_163562937.1 excinuclease ABC subunit UvrC Machinery gene
  G3M69_RS02685 (G3M69_02685) - 577155..577616 (-) 462 WP_077657861.1 hypothetical protein -
  G3M69_RS02690 (G3M69_02690) - 577608..577787 (+) 180 WP_000468798.1 hypothetical protein -
  G3M69_RS02695 (G3M69_02695) - 577791..578441 (-) 651 WP_001935889.1 ATP-binding cassette domain-containing protein -
  G3M69_RS02700 (G3M69_02700) - 578444..580105 (-) 1662 WP_163562938.1 glycine betaine ABC transporter substrate-binding protein -
  G3M69_RS02705 (G3M69_02705) - 580174..580611 (-) 438 WP_001039460.1 hypothetical protein -
  G3M69_RS02710 (G3M69_02710) motB 580617..581390 (-) 774 WP_001085363.1 flagellar motor protein MotB -

Sequence

Protein


Download         Length: 594 a.a.        Molecular weight: 68657.82 Da        Isoelectric Point: 9.7127

>NTDB_id=421668 G3M69_RS02680 WP_163562937.1 575370..577154(-) (uvrC) [Helicobacter pylori strain GCT 97]
MADLLSSLKNLSSSSGVYQYFDKNRQLLYIGKAKNLKKRIKSYFSIRNNEITPNPRASLRIQMMVKQIAFLETILVENEQ
DALILENSLIKQLKPKYNILLRDDKTYPYIYMDFSTDFPIPLITRKILKQPGVKYFGPFTSGAKDILDSLYELLPLVQKK
NCIKDKKACMFYQIERCKAPCEDKITKEEYLKIAKECLEMIENKDRLIKELELKMERLSSNLRFEEALIYRDRIAKIQKI
APFTCMDLAKLYDLDIFAFYGGNNKAVLVKMFMRGGKIISSAFEKIHSLNGFDTDEAMKQAIINHYQSHLPLMPEQILLS
ACSNEVLKELQEFISHQYSKKIALNIPKKGDKLALIEIAMKNAQEIFSQEKTSNEDRILEEARSLFNLECVPYRVEIFDT
SHHSNSQCVGGMVVYENNAFQKNSYRRYHLKGSNEYDQMSELLTRRALDFAKEPPPNLWVIDGGRAQLNIALEILKSSGS
FVEVIAISKEKRDSKAYRSKGGAKDIIHTPSDTFKLLPSDKRLQWVQKLRDESHRYAINFHRSTKLKNMKQIALLKEKGI
GEASVKKLLDYFGSFEAIEKASEQEKNAVLKKRK

Nucleotide


Download         Length: 1785 bp        

>NTDB_id=421668 G3M69_RS02680 WP_163562937.1 575370..577154(-) (uvrC) [Helicobacter pylori strain GCT 97]
ATGGCTGATTTATTATCCAGTTTGAAAAACCTTTCTAGTAGTAGTGGCGTGTATCAATATTTTGATAAAAACCGCCAATT
ACTCTACATCGGTAAGGCGAAAAATTTAAAAAAGCGCATCAAAAGCTATTTTTCCATCCGTAATAATGAAATCACGCCCA
ATCCTCGTGCAAGCTTACGCATCCAAATGATGGTCAAACAAATCGCTTTTTTAGAAACCATTTTAGTGGAAAACGAGCAA
GACGCTTTGATTTTGGAAAATTCTTTAATCAAGCAGCTCAAGCCTAAATACAATATTCTTTTAAGAGATGATAAAACTTA
CCCTTATATTTACATGGATTTTTCCACTGATTTCCCTATCCCTTTAATCACACGAAAAATTTTAAAACAGCCTGGCGTTA
AATATTTTGGCCCTTTTACGAGTGGGGCTAAGGATATTTTGGACAGCTTGTATGAATTGCTCCCGTTAGTTCAAAAGAAA
AATTGCATTAAGGATAAAAAGGCATGCATGTTTTATCAAATAGAGCGTTGCAAAGCCCCATGCGAGGATAAAATCACCAA
AGAAGAGTATTTAAAAATCGCTAAAGAATGTTTAGAAATGATTGAAAATAAAGACAGGCTCATCAAAGAGCTTGAATTGA
AAATGGAGCGCCTTTCTAGTAACTTGCGTTTTGAAGAAGCCCTCATTTACAGGGATAGGATTGCTAAAATCCAAAAAATC
GCCCCTTTCACTTGCATGGATTTAGCCAAACTCTACGATCTGGATATTTTTGCTTTTTATGGTGGGAACAACAAGGCGGT
GTTAGTGAAAATGTTCATGCGCGGAGGTAAAATCATTTCTTCAGCGTTTGAAAAAATCCACTCCCTTAATGGGTTTGACA
CCGATGAAGCGATGAAACAAGCCATTATCAATCATTACCAATCGCATTTGCCTTTAATGCCTGAACAGATCTTATTGAGC
GCTTGCTCCAATGAAGTGCTTAAAGAATTGCAAGAATTTATCTCTCATCAATATTCTAAAAAAATCGCTCTTAATATCCC
TAAAAAGGGCGATAAACTCGCTTTAATAGAAATCGCTATGAAAAACGCTCAAGAGATTTTTAGCCAAGAAAAAACCTCTA
ATGAAGATCGGATTTTAGAAGAAGCGCGATCGCTTTTCAATTTAGAGTGCGTGCCTTATAGGGTGGAAATCTTTGATACA
AGCCACCATTCAAACAGCCAATGCGTGGGGGGAATGGTCGTGTATGAAAACAATGCATTCCAAAAAAACTCTTACCGGCG
CTACCATTTAAAAGGCTCTAACGAATACGATCAAATGAGCGAATTGCTCACTAGAAGAGCTTTAGACTTTGCCAAAGAGC
CACCGCCTAATTTGTGGGTAATAGATGGAGGGAGGGCGCAATTAAACATCGCTTTAGAAATTTTAAAAAGCAGCGGGAGT
TTTGTAGAAGTGATCGCTATTTCTAAAGAAAAAAGGGATTCTAAAGCTTATCGCTCTAAAGGGGGCGCTAAAGACATTAT
CCATACGCCTAGCGATACTTTTAAATTGCTCCCTAGCGACAAACGCTTGCAGTGGGTGCAAAAATTGCGCGATGAAAGCC
ACCGGTATGCGATAAACTTCCACAGATCCACTAAACTTAAAAACATGAAACAAATCGCTCTTTTAAAAGAAAAGGGCATA
GGAGAAGCCAGCGTGAAAAAATTGTTGGATTATTTTGGGAGTTTTGAAGCGATAGAAAAAGCGAGCGAGCAGGAAAAAAA
CGCCGTTTTAAAAAAACGAAAATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-239)

GIY-YIG catalytic domain (GIY-YIG)

(15-98)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(385-538)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

97.133

99.832

0.97

Multiple sequence alignment