Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   GZ067_RS13225 Genome accession   NZ_CP048431
Coordinates   2694553..2695269 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain SA1428     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2689553..2700269
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GZ067_RS13205 (GZ067_13200) - 2690645..2691595 (+) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -
  GZ067_RS13210 (GZ067_13205) - 2691744..2693228 (+) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  GZ067_RS13215 (GZ067_13210) - 2693225..2694184 (+) 960 WP_001253302.1 carbohydrate kinase -
  GZ067_RS13220 (GZ067_13215) - 2694372..2694481 (-) 110 Protein_2567 hypothetical protein -
  GZ067_RS13225 (GZ067_13220) agrA 2694553..2695269 (-) 717 WP_000688498.1 LytTR family DNA-binding domain-containing protein Regulator
  GZ067_RS13230 (GZ067_13225) - 2695288..2696580 (-) 1293 WP_206208709.1 GHKL domain-containing protein -
  GZ067_RS13235 (GZ067_13230) - 2696605..2696745 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide -
  GZ067_RS13240 (GZ067_13235) agrB 2696742..2697311 (-) 570 WP_164026409.1 accessory gene regulator AgrB -
  GZ067_RS14035 (GZ067_13240) - 2697547..2697681 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  GZ067_RS13250 (GZ067_13245) - 2698277..2699062 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  GZ067_RS13255 (GZ067_13250) - 2699423..2700049 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=421317 GZ067_RS13225 WP_000688498.1 2694553..2695269(-) (agrA) [Staphylococcus aureus strain SA1428]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=421317 GZ067_RS13225 WP_000688498.1 2694553..2695269(-) (agrA) [Staphylococcus aureus strain SA1428]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment