Detailed information
Bioinformatically predicted
Overview
| Name | clpE | Type | Regulator |
| Locus tag | D39N_RS01565 | Genome accession | NZ_CP061208 |
| Coordinates | 306515..308620 (+) | Length | 701 a.a. |
| NCBI ID | WP_212551732.1 | Uniprot ID | - |
| Organism | Streptococcus pneumoniae strain D39_P0 | ||
| Function | repress competence development (at the early growth phase) (predicted from homology) Competence regulation |
||
Genomic Context
Location: 301515..313620
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| D39N_RS01550 (D39N_00309) | ftsL | 302403..302720 (+) | 318 | WP_000818547.1 | cell division protein FtsL | - |
| D39N_RS01555 (D39N_00310) | pbp2X | 302724..304976 (+) | 2253 | WP_000872267.1 | penicillin-binding protein 2X | - |
| D39N_RS01560 (D39N_00311) | mraY | 304978..305958 (+) | 981 | WP_000470833.1 | phospho-N-acetylmuramoyl-pentapeptide- transferase | - |
| D39N_RS01565 (D39N_00312) | clpE | 306515..308620 (+) | 2106 | WP_212551732.1 | ATP-dependent Clp protease ATP-binding subunit | Regulator |
| D39N_RS01570 (D39N_00313) | - | 308916..309398 (-) | 483 | WP_000032550.1 | S-ribosylhomocysteine lyase | - |
| D39N_RS01575 (D39N_00314) | - | 309493..310977 (-) | 1485 | WP_000743599.1 | DUF1846 domain-containing protein | - |
| D39N_RS01580 (D39N_00315) | - | 311130..312737 (+) | 1608 | WP_001156772.1 | alpha-glucosidase | - |
| D39N_RS01585 (D39N_00316) | - | 312896..313069 (+) | 174 | WP_001022228.1 | S-ribosylhomocysteinase | - |
Sequence
Protein
Download Length: 701 a.a. Molecular weight: 77574.28 Da Isoelectric Point: 4.6355
>NTDB_id=420919 D39N_RS01565 WP_212551732.1 306515..308620(+) (clpE) [Streptococcus pneumoniae strain D39_P0]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRDLINGREVTPEEFAYYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEVVARAICRNRAGFDEGNRPIGNFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRDLINGREVTPEEFAYYRATGQLPGNAESDVQMQQQASGMKQDGVLAKLG
RNLTAEAREGKLDPVIGRNKEIQEASEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIVSIDISGL
EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRNTI
LKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAA
QHPVTDVHAVEREIETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTGIPVSQMGA
SDIERLKDMAHRLQDKVIGQDKAVEVVARAICRNRAGFDEGNRPIGNFLFVGSTGVGKTELAKQLALDMFGTQDAIIRLD
MSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNT
VIIATSNAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLAEVNQTLAKKDIDLVVS
QAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLDAKHLEADMEDGVLVIREKV
Nucleotide
Download Length: 2106 bp
>NTDB_id=420919 D39N_RS01565 WP_212551732.1 306515..308620(+) (clpE) [Streptococcus pneumoniae strain D39_P0]
ATGAACAACAATTTTAATAATTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGACGTGACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTTACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGTGCAAATGCAACAACAGGCTTCAGGTATGAAACAAGATGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAGCATCTGA
AATCCTCTCACGCCGTACCAAGAACAATCCTGTTTTAGTCGGAGACGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCC
TAGCGCAAGCGATTGTGAACGGCGATGTCCCAGCTGCTATTAAGAACAAGGAAATTGTTTCCATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCTGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAACTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGTTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA
ATGAACAACAATTTTAATAATTTTAACAACATGGATGATTTATTTAACCAATTGATGGGTGGTATGCGAGGATACAGTTC
TGAAAATCGACGTGACTTGATTAATGGACGTGAAGTGACACCTGAGGAATTTGCTTACTATCGTGCAACTGGTCAATTGC
CAGGAAATGCAGAATCTGATGTGCAAATGCAACAACAGGCTTCAGGTATGAAACAAGATGGTGTCCTTGCTAAACTGGGT
CGAAACTTGACAGCAGAAGCGCGTGAGGGCAAGCTGGATCCTGTTATCGGACGAAACAAGGAAATTCAAGAAGCATCTGA
AATCCTCTCACGCCGTACCAAGAACAATCCTGTTTTAGTCGGAGACGCAGGTGTTGGTAAGACAGCCGTTGTCGAAGGCC
TAGCGCAAGCGATTGTGAACGGCGATGTCCCAGCTGCTATTAAGAACAAGGAAATTGTTTCCATTGATATCTCAGGTCTT
GAGGCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATGTCCAAAACTTAGTCAATGAAGTGAAAGAAGCAGGGAATAT
TATCCTCTTCTTTGATGAAATTCACCAAATTCTTGGTGCTGGTAGCACTGGTGGAGACAGTGGTTCTAAAGGACTTGCGG
ATATTCTCAAGCCAGCTCTCTCTCGTGGAGAATTGACAGTGATTGGGGCAACAACTCAAGACGAATACCGTAACACCATC
TTGAAGAATGCTGCTCTTGCTCGTCGTTTCAACGAAGTGAAGGTCAATGCTCCTTCGGCAGAGAATACTTTTAAAATTCT
TCAAGGAATTCGTGACCTCTATCAACAACACCACAATGTCATCTTGCCAGACGAAGTCTTGAAAGCAGCGGTGGATTATT
CTGTTCAATACATTCCTCAACGTAGCTTGCCAGATAAGGCTATTGACCTTGTCGATGTAACGGCTGCTCACTTGGCGGCT
CAACATCCAGTAACAGATGTGCATGCTGTTGAACGAGAAATCGAAACGGAAAAAGACAAGCAAGAAAAAGCAGTTGAAGC
AGAAGATTTTGAAGCAGCTCTAAACTATAAAACACGCATTGCAGAATTGGAAAGGAAAATCGAAAACCACACAGAAGATA
TGAAAGTGACTGCAAGTGTCAACGATGTGGCTGAATCTGTGGAACGAATGACAGGTATCCCAGTATCGCAAATGGGAGCT
TCAGATATCGAACGTTTGAAAGATATGGCTCATCGCTTGCAAGACAAGGTGATTGGTCAAGATAAGGCCGTAGAAGTTGT
AGCTCGTGCTATCTGTCGTAACCGTGCTGGTTTTGATGAAGGAAATCGCCCAATCGGCAACTTCCTCTTTGTAGGGTCTA
CTGGGGTTGGTAAGACGGAGCTTGCTAAGCAATTGGCACTCGATATGTTTGGAACCCAGGATGCGATTATCCGTTTGGAT
ATGTCTGAATACAGTGACCGCACAGCTGTTTCTAAGTTAATTGGTACAACAGCAGGCTATGTGGGTTATGATGACAATAG
CAATACCTTAACAGAACGTGTTCGTCGCAATCCATACTCTATCATTCTCTTGGATGAAATTGAAAAGGCTGACCCTCAAG
TTATTACCCTTCTCCTCCAAGTTCTAGATGATGGTCGTTTGACAGATGGTCAAGGAAATACAGTAAACTTCAAGAACACT
GTCATTATTGCGACCTCAAATGCTGGATTTGGCTATGAAGCCAACTTGACAGAAGATGCGGATAAACCAGAATTGATGGA
CCGTTTGAAACCCTTCTTCCGTCCAGAATTCCTCAACCGCTTTAATGCAGTCATCGAGTTCTCACACTTGACTAAGGAAG
ACCTTTCTAAGATTGTAGATTTGATGTTGGCTGAAGTTAACCAAACCTTGGCTAAGAAAGACATTGACTTGGTAGTCAGT
CAAGCGGCTAAAGATTATATCACAGAAGAAGGTTACGACGAAGTCATGGGGGTTCGTCCTCTCCGTCGCGTGGTTGAACA
AGAAATTCGTGATAAGGTGACAGACTTCCACTTGGATCATTTAGATGCTAAACATCTGGAAGCAGATATGGAAGATGGCG
TTTTGGTTATTCGTGAGAAAGTCTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| clpE | Streptococcus mutans UA159 |
46.571 |
99.857 |
0.465 |
| clpC | Lactococcus lactis subsp. cremoris KW2 |
49.531 |
91.298 |
0.452 |
| clpE | Streptococcus pneumoniae Rx1 |
47.31 |
90.157 |
0.427 |
| clpE | Streptococcus pneumoniae D39 |
47.31 |
90.157 |
0.427 |
| clpE | Streptococcus pneumoniae R6 |
47.31 |
90.157 |
0.427 |
| clpE | Streptococcus pneumoniae TIGR4 |
47.235 |
90.3 |
0.427 |
| clpC | Bacillus subtilis subsp. subtilis str. 168 |
44.427 |
92.154 |
0.409 |
| clpC | Streptococcus pneumoniae Rx1 |
42.448 |
89.729 |
0.381 |
| clpC | Streptococcus pneumoniae D39 |
42.448 |
89.729 |
0.381 |
| clpC | Streptococcus pneumoniae TIGR4 |
42.289 |
89.729 |
0.379 |
| clpC | Lactococcus lactis subsp. lactis strain DGCC12653 |
42.626 |
88.017 |
0.375 |
| clpC | Streptococcus thermophilus LMD-9 |
42.419 |
88.445 |
0.375 |
| clpC | Streptococcus thermophilus LMG 18311 |
42.258 |
88.445 |
0.374 |
| clpC | Streptococcus mutans UA159 |
41.586 |
88.16 |
0.367 |