Detailed information NTG0420536

Bioinformatically predicted

Overview

• Name: xerS
• Type: Machinery gene
• Locus tag: IB935_RS04840
• Genome accession: NZ_CP061134
• Coordinates: 957163..958233 (-)
• Length: 356 a.a.
• NCBI ID: WP_002984598.1
• Uniprot ID: P0DH45
• Organism: Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 952163..963233

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IB935_RS04820 (IB935_04820)	citX	952743..953321 (+)	579	WP_021299257.1	citrate lyase holo-[acyl-carrier protein] synthase	-
IB935_RS04825 (IB935_04825)	-	953336..954730 (+)	1395	WP_187835560.1	oxaloacetate decarboxylase subunit alpha	-
IB935_RS04830 (IB935_04830)	citC	954840..955892 (-)	1053	WP_011528662.1	[citrate (pro-3S)-lyase] ligase	-
IB935_RS04835 (IB935_04835)	-	955981..956463 (-)	483	WP_002984600.1	PASTA domain-containing protein	-
IB935_RS04840 (IB935_04840)	xerS	957163..958233 (-)	1071	WP_002984598.1	tyrosine recombinase XerS	Machinery gene
IB935_RS04845 (IB935_04845)	-	958707..959405 (+)	699	WP_011528664.1	XRE family transcriptional regulator	-
IB935_RS04850 (IB935_04850)	ffh	959522..961084 (-)	1563	WP_021299250.1	signal recognition particle protein	-
IB935_RS04855 (IB935_04855)	-	961099..961431 (-)	333	WP_002989745.1	putative DNA-binding protein	-
IB935_RS04860 (IB935_04860)	-	961529..962227 (-)	699	WP_021299253.1	GntR family transcriptional regulator	-

Sequence

Protein

• Length: 356 a.a.
• Molecular weight: 41471.57 Da
• Isoelectric Point: 9.5552

>NTDB_id=420536 IB935_RS04840 WP_002984598.1 957163..958233(-) (xerS) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
MRRELLLEKIETYKAIMPWYVLDYYQSKLAVPYSFTTLYEYLKEYKRFFDWLMDADLTQAPKIADIDLSTLEHLTKKDLE
AFVLYLRERPSLNTYSTKEGLSQTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLASRAENIKQK
LFLGDETLAFLDYVDKEYEQKLSNRAKSSFRKNKERDLAIIALLLASGVRLSEAVNLDLKDVNLNMMIIEVIRKGGKRDS
VNVAGFAKGYLESYLAVRQRRYKAEKQDLAFFLTEYRGVPNRMDASSIEKMVGKYSEDFKIRVTPHKLRHTLATRLYDAT
KSQVLVSHQLGHSSTQVTDLYTHIVNDEQKNALDNL

Nucleotide

• Length: 1071 bp

>NTDB_id=420536 IB935_RS04840 WP_002984598.1 957163..958233(-) (xerS) [Streptococcus pyogenes strain BSAC_bs192 isolate Invasive disease]
ATGAGACGCGAATTATTACTAGAAAAAATTGAAACCTACAAGGCTATCATGCCTTGGTATGTTTTAGATTATTACCAATC
CAAATTAGCTGTTCCATACAGCTTTACCACCTTATATGAGTATTTAAAAGAATACAAACGCTTTTTTGATTGGCTGATGG
ATGCTGATTTAACGCAGGCGCCAAAGATTGCTGATATTGACTTGAGCACGCTTGAGCACCTTACCAAGAAGGATTTAGAG
GCCTTTGTGCTTTATTTGCGGGAACGACCTTCTCTCAACACCTATTCCACCAAAGAGGGGCTTTCTCAAACCACTATTAA
TCGGACCTTGTCTGCCCTATCAAGCCTTTACAAGTACTTGACTGAAGAGGTTGAAAATGACCAAGGAGAGCCTTATTTTT
ATCGGAATGTTATGAAAAAAGTGTCAACAAAAAAGAAAAAAGAAACCCTGGCTTCCAGAGCGGAAAATATTAAGCAGAAA
CTGTTTTTAGGTGATGAAACTCTAGCTTTCTTGGATTATGTGGATAAGGAATATGAGCAAAAATTGTCTAATCGTGCCAA
ATCTTCTTTCCGTAAAAATAAGGAGAGGGATTTGGCTATTATTGCTCTACTACTTGCTTCTGGTGTTCGTTTGTCTGAAG
CAGTGAATCTTGATTTAAAAGATGTCAATCTAAATATGATGATTATCGAAGTTATTCGCAAAGGCGGAAAACGTGATTCA
GTCAATGTAGCAGGTTTTGCGAAAGGTTATTTGGAGTCTTATCTAGCTGTTCGTCAGAGACGTTACAAGGCTGAAAAACA
GGATCTTGCTTTCTTTTTAACAGAATACCGTGGCGTTCCAAATCGAATGGATGCTTCTAGTATAGAAAAGATGGTTGGCA
AGTACTCTGAGGATTTTAAAATTCGTGTGACTCCTCACAAATTGCGTCATACGCTAGCGACAAGACTATATGATGCTACT
AAATCTCAGGTGTTAGTTAGTCATCAATTAGGCCATTCCTCTACTCAAGTCACGGATCTTTATACCCATATTGTCAATGA
TGAGCAAAAAAATGCTTTAGATAACCTTTAA

Domains

Predicted by InterProScan.

• Phage integrase family (Phage_integrase) (177-344)

• Phage integrase, N-terminal SAM-like domain (Phage_int_SAM_4) (33-122)

3D structure

• AlphaFold DB: P0DH45

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
xerS	Streptococcus pneumoniae R6	80.618	100	0.806