Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Regulator
Locus tag   M654_RS05340 Genome accession   NZ_CP048273
Coordinates   1089872..1090510 (+) Length   212 a.a.
NCBI ID   WP_026588580.1    Uniprot ID   A0A6I7F976
Organism   Bacillus sp. NSP9.1     
Function   promoting transcription of comS (predicted from homology)   
Competence regulation

Genomic Context

Location: 1084872..1095510
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M654_RS05315 (M654_005310) - 1085251..1085580 (-) 330 WP_026588585.1 hypothetical protein -
  M654_RS05320 (M654_005315) degQ 1086075..1086215 (+) 141 WP_026588584.1 degradation enzyme regulation protein DegQ Regulator
  M654_RS05325 (M654_005320) - 1086402..1087283 (+) 882 WP_026588583.1 polyprenyl synthetase family protein -
  M654_RS05330 (M654_005325) comX 1087292..1087456 (+) 165 WP_026588582.1 competence pheromone ComX -
  M654_RS05335 (M654_005330) comP 1087479..1089785 (+) 2307 WP_026588581.1 ATP-binding protein Regulator
  M654_RS05340 (M654_005335) comA 1089872..1090510 (+) 639 WP_026588580.1 response regulator transcription factor Regulator
  M654_RS05345 (M654_005340) - 1090530..1090919 (+) 390 WP_026588579.1 hotdog fold thioesterase -
  M654_RS05350 (M654_005345) mnhG 1090960..1091334 (-) 375 WP_026588578.1 monovalent cation/H(+) antiporter subunit G -
  M654_RS05355 (M654_005350) - 1091318..1091602 (-) 285 WP_026588577.1 Na(+)/H(+) antiporter subunit F1 -
  M654_RS05360 (M654_005355) - 1091602..1092078 (-) 477 WP_026588576.1 Na+/H+ antiporter subunit E -
  M654_RS05365 (M654_005360) - 1092084..1093562 (-) 1479 WP_026588575.1 Na+/H+ antiporter subunit D -
  M654_RS05370 (M654_005365) - 1093555..1093896 (-) 342 WP_026588574.1 Na(+)/H(+) antiporter subunit C -
  M654_RS05375 (M654_005370) - 1093896..1094327 (-) 432 WP_026588573.1 Na(+)/H(+) antiporter subunit B -

Sequence

Protein


Download         Length: 212 a.a.        Molecular weight: 24162.49 Da        Isoelectric Point: 4.5138

>NTDB_id=420432 M654_RS05340 WP_026588580.1 1089872..1090510(+) (comA) [Bacillus sp. NSP9.1]
MRRLLVIDDHPAVMEGTKAILETNQDFIVDCLSPEASEQFLTNHDFSAYDLILMDLNLGEINGMDLSKKILETCSSCKII
VYTGYEVEDYFEEAIRSGMHGAISKTESKEKIIEYIYQVLDNKIVVDYDYFKQLITQQKTKTNSQQTEHELLTERECLIL
KEVEKGYTNQEIADALHLSKRSIEYSLTSVFSKLNVGSRTEAVLIAKSEGVL

Nucleotide


Download         Length: 639 bp        

>NTDB_id=420432 M654_RS05340 WP_026588580.1 1089872..1090510(+) (comA) [Bacillus sp. NSP9.1]
ATGAGAAGATTACTTGTGATCGATGATCATCCGGCTGTTATGGAGGGGACGAAGGCAATTCTTGAAACAAATCAGGACTT
CATTGTCGATTGCCTCAGCCCTGAAGCCAGCGAACAATTTCTGACGAACCATGATTTTTCTGCGTATGACCTGATCTTAA
TGGATTTGAATCTAGGTGAAATCAACGGAATGGACCTATCCAAGAAAATCCTTGAGACCTGTTCATCATGCAAAATTATC
GTATATACCGGATATGAGGTGGAAGATTATTTTGAAGAAGCGATTCGTTCAGGTATGCACGGCGCGATCAGCAAGACGGA
ATCAAAAGAAAAGATCATCGAGTACATATACCAGGTGTTGGACAATAAAATTGTCGTCGACTACGATTATTTTAAACAGC
TGATTACACAGCAAAAGACGAAGACAAACAGCCAGCAGACCGAGCACGAGCTTTTGACAGAAAGGGAATGCCTGATTCTG
AAAGAAGTTGAAAAAGGCTATACGAATCAGGAGATTGCCGATGCCCTCCATTTGAGCAAGCGCTCGATTGAATACAGTCT
GACGTCGGTATTCAGCAAGCTGAATGTCGGCTCGCGGACCGAGGCTGTGCTGATCGCGAAATCCGAAGGTGTACTGTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(151-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6I7F976

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Bacillus subtilis subsp. subtilis str. 168

77.103

100

0.778

Multiple sequence alignment