Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   SPPN_RS09950 Genome accession   NC_015875
Coordinates   1911450..1912280 (-) Length   276 a.a.
NCBI ID   WP_001036778.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 1906450..1917280
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS14250 - 1909586..1909720 (-) 135 WP_259390846.1 hypothetical protein -
  SPPN_RS09940 (SPPN_10075) - 1909782..1911113 (-) 1332 WP_000390028.1 hemolysin family protein -
  SPPN_RS09950 (SPPN_10080) endA 1911450..1912280 (-) 831 WP_001036778.1 DNA/RNA non-specific endonuclease Machinery gene
  SPPN_RS09955 (SPPN_10085) - 1912319..1912507 (-) 189 WP_044012464.1 DNA-directed RNA polymerase subunit beta -
  SPPN_RS09960 (SPPN_10090) murA 1912500..1913783 (-) 1284 WP_000358020.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPPN_RS09965 (SPPN_10095) - 1913807..1914037 (-) 231 WP_014017351.1 DUF1146 family protein -
  SPPN_RS09970 (SPPN_10100) sepM 1914095..1915132 (-) 1038 WP_000727282.1 SepM family pheromone-processing serine protease Regulator
  SPPN_RS09975 (SPPN_10105) coaD 1915116..1915604 (-) 489 WP_001280725.1 pantetheine-phosphate adenylyltransferase -
  SPPN_RS09980 (SPPN_10110) rsmD 1915594..1916133 (-) 540 WP_000706954.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPPN_RS09985 (SPPN_10115) asnA 1916198..1917190 (-) 993 WP_000748004.1 aspartate--ammonia ligase -

Sequence

Protein


Download         Length: 276 a.a.        Molecular weight: 30052.60 Da        Isoelectric Point: 9.9527

>NTDB_id=42025 SPPN_RS09950 WP_001036778.1 1911450..1912280(-) (endA) [Streptococcus pseudopneumoniae IS7493]
MNKKTRQTLIGLLVLLLLSAGSYYIKQNELGNQAAKTKMSQKSQSPDAPGQALAESVLTDAVKNQVKGSLEWNGSGAFIV
NGNKTNLNAKVSSKPYADNKTKTVGKETVPTVANALLSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESKVRKALDQNKRVRYRVTLYYASNEDLVPSASQIE
AKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTHTQ

Nucleotide


Download         Length: 831 bp        

>NTDB_id=42025 SPPN_RS09950 WP_001036778.1 1911450..1912280(-) (endA) [Streptococcus pseudopneumoniae IS7493]
ATGAACAAAAAAACAAGACAGACACTGATTGGCTTGCTAGTGTTATTGCTCTTATCTGCGGGGAGCTATTATATCAAGCA
GAATGAACTAGGCAATCAGGCTGCTAAGACAAAAATGAGTCAGAAAAGTCAATCACCAGACGCGCCTGGTCAAGCATTGG
CAGAGAGTGTCTTAACAGACGCAGTCAAAAACCAAGTAAAAGGGAGTCTGGAGTGGAACGGATCAGGTGCTTTTATCGTC
AATGGTAATAAAACAAACCTAAATGCCAAGGTTTCAAGTAAGCCCTACGCTGATAATAAAACAAAGACGGTGGGCAAGGA
GACCGTACCAACCGTGGCTAATGCCCTCTTGTCTAAGGCTACTCGTCAGTACAAGAATCGTGAAGAAACTGGGAATGGTT
CGACTTCATGGACTCCTCCAGGCTGGCATCAGGTCAAGAATCTAAAGGGCTCTTATACCCATGCAGTCGATAGAGGTCAT
CTGTTAGGCTATGCCTTAATCGGTGGTTTGGATGGTTTTGATGCCTCGACAAGCAATCCTAAAAACATTGCTGTTCAGAC
AGCCTGGGCAAATCAGGCGCAGGCCGAGGATTCGACTGGTCAAAACTACTATGAAAGTAAGGTGCGTAAAGCCTTGGACC
AAAACAAGCGTGTCCGTTACCGTGTAACCCTTTACTACGCTTCAAACGAGGATTTAGTTCCTTCAGCTTCACAGATTGAA
GCCAAGTCTTCAGATGGAGAATTGGAATTTAATGTTCTAGTTCCCAATGTTCAAAAGGGGCTTCAACTGGATTACCGAAC
TGGAGAAGTCACTGTTACTCATACTCAATGA

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(75-247)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

91.971

99.275

0.913
  endA Streptococcus pneumoniae D39

91.971

99.275

0.913
  endA Streptococcus pneumoniae R6

91.971

99.275

0.913
  endA Streptococcus pneumoniae TIGR4

91.971

99.275

0.913

Multiple sequence alignment