Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   GYN05_RS10680 Genome accession   NZ_CP048250
Coordinates   2045922..2047175 (+) Length   417 a.a.
NCBI ID   WP_250328967.1    Uniprot ID   -
Organism   Neisseria gonorrhoeae strain CT532     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2040922..2052175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GYN05_RS10660 (GYN05_10425) - 2041669..2042670 (+) 1002 WP_003686999.1 thiamine ABC transporter substrate-binding protein -
  GYN05_RS10665 (GYN05_10430) - 2042764..2043612 (+) 849 WP_250328966.1 mechanosensitive ion channel family protein -
  GYN05_RS10670 (GYN05_10435) - 2043639..2044124 (+) 486 WP_003687001.1 CinA family protein -
  GYN05_RS10675 (GYN05_10440) msrAB 2044208..2045776 (-) 1569 WP_003694393.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  GYN05_RS10680 (GYN05_10445) pilA 2045922..2047175 (+) 1254 WP_250328967.1 signal recognition particle-docking protein FtsY Machinery gene
  GYN05_RS10685 - 2047253..2047426 (-) 174 WP_164823228.1 hypothetical protein -
  GYN05_RS10690 (GYN05_10450) - 2047440..2048270 (-) 831 WP_250329010.1 opacity family porin -
  GYN05_RS10695 (GYN05_10455) - 2048681..2049198 (-) 518 Protein_2075 pilin -
  GYN05_RS10700 (GYN05_10460) - 2049567..2049710 (-) 144 WP_050171575.1 hypothetical protein -
  GYN05_RS10705 - 2049815..2049895 (-) 81 Protein_2077 pilin -
  GYN05_RS10710 (GYN05_10465) - 2049969..2050364 (-) 396 Protein_2078 pilin -
  GYN05_RS10715 (GYN05_10470) - 2050472..2050879 (-) 408 Protein_2079 pilin -
  GYN05_RS10720 (GYN05_10475) lpxC 2051008..2051931 (-) 924 WP_003687007.1 UDP-3-O-acyl-N-acetylglucosamine deacetylase -

Sequence

Protein


Download         Length: 417 a.a.        Molecular weight: 44373.74 Da        Isoelectric Point: 4.8152

>NTDB_id=420212 GYN05_RS10680 WP_250328967.1 2045922..2047175(+) (pilA) [Neisseria gonorrhoeae strain CT532]
MFSFFRRKKKQETPALEEAQVQETAAKVESEVAQIVGNIKEDVESLAESVKGRAESAVETVSGAVEQVKETVAEMPSEAG
EAAERVESAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLAKSRDKMAKSLAGVFGGGQIGEDLYEELETVLIT
GDMGMEATEYLMKDVRGRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGKLAKY
FQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTAGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHLMEEI
KKVKRVLQKAIPGAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGVGEGI
DDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1254 bp        

>NTDB_id=420212 GYN05_RS10680 WP_250328967.1 2045922..2047175(+) (pilA) [Neisseria gonorrhoeae strain CT532]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCCCAAGTTCAGGAAACCGCAGCAAA
AGTAGAATCTGAAGTTGCTCAAATAGTTGGAAATATTAAAGAAGATGTCGAATCTTTAGCAGAAAGCGTCAAAGGGCGGG
CCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCCGTCTGAAGCAGGG
GAAGCGGCGGAACGCGTTGAATCCGCAAAAGAAGCTGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCAAGTTCAAGAAGC
CGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCTGCGCGTTTGAAACAAGGCTTGGCCAAATCACGCGACAAAATGG
CGAAATCGCTGGCCGGCGTGTTCGGCGGCGGACAAATCGGCGAGGATTTGTACGAAGAGCTGGAAACCGTGCTGATTACC
GGCGATATGGGCATGGAGGCCACCGAATACCTGATGAAAGACGTGCGCGGCCGCGTCAGCCTCAAAGGGCTGAAAGACGG
CAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCGTTGGAAAAACCGCTGGTCTTGCCCGAAA
CTAAAGAGCCTTTCGTGATTATGCTTGCCGGTATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAACTCGCCAAATAT
TTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGCGCCGCCGCGCGCGAGCAGCTTCAGGCTTG
GGGCGAACGCAACAATGTAACCGTCATTTCACAAACTGCGGGCGATTCCGCCGCCGTGTGCTTCGATGCCGTCCAAGCCG
CGAAAGCGCGCGGGATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTGATGGAAGAAATC
AAAAAAGTGAAGCGCGTGCTGCAAAAAGCCATTCCCGGCGCGCCGCACGAAATTATCGTCGTACTCGATGCCAATATCGG
GCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACGGGGCTTATCGTTACCAAACTCGACGGCA
CGGCAAAAGGCGGCATCCTCGCCGCGCTTGCTTCCGACCGCCCCGTCCCCGTCCGCTACATCGGCGTGGGCGAAGGCATA
GACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(132-198)

SRP54-type protein, GTPase domain (SRP54)

(217-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

99.52

100

0.995

Multiple sequence alignment