Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   SPPN_RS06440 Genome accession   NC_015875
Coordinates   1246558..1248792 (-) Length   744 a.a.
NCBI ID   WP_000942433.1    Uniprot ID   -
Organism   Streptococcus pseudopneumoniae IS7493     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1245812..1246099 1246558..1248792 flank 459


Gene organization within MGE regions


Location: 1245812..1248792
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPPN_RS12110 - 1245815..1246500 (-) 686 Protein_1306 transposase family protein -
  SPPN_RS06440 (SPPN_06535) comEC/celB 1246558..1248792 (-) 2235 WP_000942433.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene

Sequence

Protein


Download         Length: 744 a.a.        Molecular weight: 84426.61 Da        Isoelectric Point: 9.2904

>NTDB_id=42002 SPPN_RS06440 WP_000942433.1 1246558..1248792(-) (comEC/celB) [Streptococcus pseudopneumoniae IS7493]
MLQWIKNIPIPLIYLSFLLLWFYYAIFSASYLALLGFVFLLVCLFFQFPWKSTGKVLVICGVFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKADGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSESEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVFLLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVASESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFALSFLYPVIQLNFIFEWLEGMIRLVSQMTSRPFVFGQPNAWFLILLLISLALVYDLRKNIKRVAGFSLLIVGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESDKKIEKWQEKATTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
EHVGDLLEVTKAFHVGEILVSKGSLKQKEFVAELQATQTKVRSVTAGENLPIFGSQLEVLSPRKIGDHEDTLVLYGKLLD
KNFLFTGNLEEKGEKDMLKHYPDLEVDVLKASQHGSKKSLSSDFLEQLKPEMTLISVGKNNRTKLPHQETLTRLEGINSK
VYRTDKQGAIRFKGWNSWKIESVR

Nucleotide


Download         Length: 2235 bp        

>NTDB_id=42002 SPPN_RS06440 WP_000942433.1 1246558..1248792(-) (comEC/celB) [Streptococcus pseudopneumoniae IS7493]
ATGTTACAGTGGATTAAGAACATCCCCATTCCCCTAATTTACCTGAGTTTTTTGTTACTTTGGTTTTATTACGCTATTTT
CTCAGCATCCTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTTTCCAATTTCCATGGAAATCAACAG
GCAAAGTTTTAGTGATTTGTGGAGTCTTTGGCTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGCCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTCTGCCTGACACTGTTAAGGTCAATGGTGATAGTCTGTCCTTTCGCGGCAA
GGCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGTCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAACGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACAGTGTTTCTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTGCTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCCATCCTCTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATC
TTATTTGCCCTTTCCTTTCTCTATCCAGTCATTCAACTGAATTTTATCTTTGAATGGTTGGAGGGAATGATTCGCTTGGT
CTCGCAGATGACAAGTAGGCCGTTTGTCTTTGGACAACCTAATGCATGGTTTTTAATTTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAATATCAAAAGAGTAGCTGGCTTCAGCTTACTTATTGTGGGTCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATTACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTAAGGGATGTAACTGGGAAGAC
CATTCTCATAGATGTAGGTGGCAAGGCAGAATCTGATAAGAAAATTGAAAAATGGCAAGAAAAGGCGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCCAAGATTGACCAGCTGATTTTGACAAATACGGACAAG
GAACATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTTCATGTAGGGGAGATTTTAGTATCAAAAGGAAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACCAAGGTGCGCAGTGTGACAGCAGGAGAGAACTTGCCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATCATGAAGATACCCTGGTTTTGTATGGAAAACTCTTGGAT
AAAAACTTTCTTTTCACTGGAAATTTGGAGGAGAAAGGAGAGAAGGACATGCTGAAGCACTATCCTGACCTAGAAGTGGA
TGTTTTGAAAGCTAGCCAACATGGCTCTAAAAAATCATTAAGTTCAGACTTTTTAGAACAGCTCAAACCAGAGATGACTC
TCATCTCAGTTGGAAAGAACAATCGAACGAAACTCCCCCATCAGGAAACTTTGACACGACTGGAAGGTATCAATAGCAAA
GTTTACCGAACTGACAAGCAAGGAGCTATACGCTTTAAGGGGTGGAATAGTTGGAAGATTGAAAGCGTTCGATAG

Domains

Predicted by InterproScan.

Metallo-beta-lactamase superfamily (Lactamase_B)

(492-689)

Competence protein (Competence)

(216-458)

Domain of unknown function (DUF4131) (DUF4131)

(30-176)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

92.225

100

0.925
  comEC/celB Streptococcus pneumoniae Rx1

92.225

100

0.925
  comEC/celB Streptococcus pneumoniae D39

92.225

100

0.925
  comEC/celB Streptococcus pneumoniae R6

92.225

100

0.925
  comEC/celB Streptococcus mitis NCTC 12261

92.081

100

0.922
  comEC/celB Streptococcus pneumoniae TIGR4

91.823

100

0.921
  comEC Lactococcus lactis subsp. cremoris KW2

44.043

100

0.442

Multiple sequence alignment