Detailed information NTG0041993

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SPPN_RS04105
• Genome accession: NC_015875
• Coordinates: 795248..797506 (-)
• Length: 752 a.a.
• NCBI ID: WP_000882535.1
• Uniprot ID: -
• Organism: Streptococcus pseudopneumoniae IS7493
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 790248..802506

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPPN_RS13150	-	793755..793970 (+)	216	Protein_836	transposase	-
SPPN_RS04090 (SPPN_04150)	-	794157..794456 (-)	300	WP_000767185.1	DUF1827 family protein	-
SPPN_RS13830 (SPPN_04155)	-	794524..794670 (+)	147	WP_000693567.1	hypothetical protein	-
SPPN_RS04100 (SPPN_04160)	-	794667..795119 (-)	453	WP_000013081.1	NUDIX hydrolase	-
SPPN_RS04105 (SPPN_04165)	clpE	795248..797506 (-)	2259	WP_000882535.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
SPPN_RS04110 (SPPN_04175)	-	797736..797966 (-)	231	WP_000443574.1	DUF1797 family protein	-
SPPN_RS04115 (SPPN_04180)	-	798157..798840 (+)	684	WP_001011642.1	amino acid ABC transporter permease	-
SPPN_RS04120 (SPPN_04185)	-	798840..799574 (+)	735	WP_000140962.1	amino acid ABC transporter ATP-binding protein	-
SPPN_RS04125 (SPPN_04190)	-	799728..800585 (+)	858	WP_000192087.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
SPPN_RS04130 (SPPN_04195)	-	800726..801598 (+)	873	WP_000863090.1	NAD(P)H-hydrate dehydratase	-

Sequence

Protein

• Length: 752 a.a.
• Molecular weight: 83984.38 Da
• Isoelectric Point: 5.2298

>NTDB_id=41993 SPPN_RS04105 WP_000882535.1 795248..797506(-) (clpE) [Streptococcus pseudopneumoniae IS7493]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPP
TQSGGGYGGNGGYGSQNRGSTQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
SDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAS
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEQTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHIIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKSEANVGFGATREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDYYLENP
SEKDLKAVLTSKGNIQIKSAKKVEVKTYEKEV

Nucleotide

• Length: 2259 bp

>NTDB_id=41993 SPPN_RS04105 WP_000882535.1 795248..797506(-) (clpE) [Streptococcus pseudopneumoniae IS7493]
ATGCTTTGTCAAAACTGTAAAATCAACGACTCAACAATTCATCTTTACACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTACAAGATTATCAAAACAGATCCTAACAATAGCCTCTTCAAAGGTATGACGGATCTGAACAATC
GTGACTTCGATCCCTTTGGTGATTTCTTCAATGATCTAAACAATTTCAGACCTTCTAGCAATACTCCTCCTATTCCCCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAACGGCGGTTATGGTTCCCAAAATCGTGGATCTACTCAAACTCCGCCACCTAG
CCAAGAAAAAGGCCTGCTGGAAGAATTTGGTATTAATGTAACTGAAATTGCCCGTCGTGGAGACATTGACCCCGTTATTG
GGCGCGACGATGAGATTATCCGTGTCATCGAGATTCTCAATCGTAGAACCAAGAATAATCCTGTCCTTATCGGTGAACCT
GGTGTCGGAAAAACGGCCGTTGTCGAAGGTCTAGCTCAGAAAATTGTCGATGGCGATGTGCCACATAAACTCCAAGGTAA
ACAAGTCATCCGTCTGGATGTGGTTAGCTTAGTTCAAGGAACGGGGATTCGAGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAAGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCTGGTTCTGCG
AGTGATGGTAATATGGACGCAGGAAATATCCTCAAGCCAGCCCTTGCTCGTGGAGAACTGCAACTGGTCGGCGCTACTAC
CCTCAATGAATACCGTATCATTGAAAAGGATGCTGCCCTCGAGCGTCGTATGCAGCCTGTCAAGGTTGATGAACCAACCG
TGGAAGAAACAATCACTATCCTCAAAGGGATTCAAAAGAAATACGAAGACTACCACCACGTTCAATATACCGATGCTTCG
ATTGAAGCAGCTGCAACTCTTTCCAATCGTTACATCCAAGATCGCTTCTTACCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAATTTGACCTTGAATTTTGTAGACCCTAAAGTCATTGATCAGCGCTTGATTGAGGCTGAAAATC
TCAAGTCTCAAGCTACACGAGAAGAAGATTTTGAAAAAGCCGCCTACTTCCGTGACCAGATTGCCAAATATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAGGATACTCCAATCATCAGTGAACAAACCATTGAGCATATTATTGAGCAGAAAACCAA
CATCCCTGTTGGTGATTTAAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATATTATTG
GCCAAGATGATGCAGTCGATAAGATTGCTAAGGCTATTCGCCGTAATCGTGTCGGTCTTGGTACGCCTAACCGTCCAATT
GGAAGCTTCCTCTTTGTCGGACCAACTGGGGTCGGTAAGACAGAACTTTCCAAACAATTAGCTATCGAACTCTTTGGTTC
TGCTGATAGTATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTGGCTAAGTTGGTCGGCGCTCCTCCAG
GTTATGTTGGCTATGATGAGGCTGGTCAATTAACTGAAAAAGTTCGCCGCAATCCATATTCTCTCATCCTTCTCGATGAA
GTGGAAAAAGCTCACCCAGATGTTATGCACATGTTTCTACAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACG
GACCGTTAGCTTCAAGGATGCCATCATTATCATGACCTCAAATGCAGGTACAGGTAAGTCTGAAGCCAACGTTGGATTTG
GGGCTACTAGAGAAGGACGTACCAACTCTGTTCTCGGTGAACTCGGCAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGCATTATCGAATTTAAGGCTCTCAGCAAGGATAATCTCCTTCAGATTGTCGAGCTCATGCTAGCAGATGTTAACAA
GCGCCTCTCTAGCAACAACATTCATTTGGATGTAACTGACAAGGTCAAGGAAAAGCTGGTTGACCTAGGTTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGGACTATTCAAGACTATATTGAGGACGCAATCACTGACTACTACCTTGAAAATCCA
AGCGAAAAAGACCTCAAAGCAGTTCTGACTAGCAAGGGAAACATTCAAATTAAGTCTGCCAAAAAAGTTGAAGTAAAAAC
TTATGAAAAAGAAGTATAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (478-641)

• AAA lid domain (AAA_lid_9) (293-390)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (649-723)

• ATPase family associated with various cellular activities (AAA) (AAA) (155-276)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	97.87	99.867	0.977
clpE	Streptococcus pneumoniae D39	97.87	99.867	0.977
clpE	Streptococcus pneumoniae R6	97.87	99.867	0.977
clpE	Streptococcus pneumoniae TIGR4	97.736	99.867	0.976
clpE	Streptococcus mutans UA159	82.8	99.734	0.826
clpC	Lactococcus lactis subsp. cremoris KW2	74.704	100	0.754
clpC	Bacillus subtilis subsp. subtilis str. 168	50.215	92.686	0.465
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.528	83.378	0.396
clpC	Streptococcus pneumoniae Rx1	46.593	83.91	0.391
clpC	Streptococcus pneumoniae D39	46.593	83.91	0.391
clpC	Streptococcus pneumoniae TIGR4	46.593	83.91	0.391
clpC	Streptococcus thermophilus LMD-9	46.474	82.979	0.386
clpC	Streptococcus mutans UA159	46.314	82.979	0.384
clpC	Streptococcus thermophilus LMG 18311	46.08	83.112	0.383