Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   IBC03_RS09000 Genome accession   NZ_CP061025
Coordinates   1742413..1742706 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain 13496     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1737413..1747706
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBC03_RS08970 (IBC03_08990) - 1737940..1738137 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  IBC03_RS08975 (IBC03_08995) - 1738386..1739579 (-) 1194 WP_014608740.1 acetate kinase -
  IBC03_RS08980 (IBC03_09000) comGH 1739635..1740591 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  IBC03_RS08985 (IBC03_09005) comGG 1740636..1740956 (-) 321 WP_278249177.1 competence type IV pilus minor pilin ComGG Machinery gene
  IBC03_RS08990 (IBC03_09010) - 1740977..1741912 (-) 936 WP_138496752.1 IS30 family transposase -
  IBC03_RS08995 (IBC03_09015) comGF 1741995..1742429 (-) 435 WP_138496599.1 competence type IV pilus minor pilin ComGF Machinery gene
  IBC03_RS09000 (IBC03_09020) comGE 1742413..1742706 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  IBC03_RS09005 (IBC03_09025) comGD 1742678..1743106 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  IBC03_RS09010 (IBC03_09030) comGC 1743066..1743392 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  IBC03_RS09015 (IBC03_09035) comGB 1743389..1744489 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  IBC03_RS09020 (IBC03_09040) comGA/cglA/cilD 1744371..1745312 (-) 942 WP_014608745.1 competence type IV pilus ATPase ComGA Machinery gene
  IBC03_RS09025 (IBC03_09045) - 1745393..1745755 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=419619 IBC03_RS09000 WP_011226625.1 1742413..1742706(-) (comGE) [Streptococcus thermophilus strain 13496]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=419619 IBC03_RS09000 WP_011226625.1 1742413..1742706(-) (comGE) [Streptococcus thermophilus strain 13496]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361