Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   GWK37_RS14950 Genome accession   NZ_CP048002
Coordinates   3004121..3004777 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain CACC 316     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2999121..3009777
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWK37_RS14925 (GWK37_14935) oppF 2999650..3000567 (+) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -
  GWK37_RS14930 (GWK37_14940) - 3000674..3001861 (+) 1188 WP_115940905.1 putative glycoside hydrolase -
  GWK37_RS14935 (GWK37_14945) - 3001979..3002557 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  GWK37_RS14940 (GWK37_14950) spx 3002736..3003131 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  GWK37_RS14945 (GWK37_14955) - 3003189..3003845 (-) 657 WP_014417421.1 TerC family protein -
  GWK37_RS14950 (GWK37_14960) mecA 3004121..3004777 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  GWK37_RS14955 (GWK37_14965) - 3004929..3006089 (+) 1161 WP_094295680.1 competence protein CoiA family protein -
  GWK37_RS14960 (GWK37_14970) pepF 3006317..3008146 (+) 1830 WP_115940977.1 oligoendopeptidase F Regulator
  GWK37_RS19640 - 3008184..3008351 (-) 168 WP_003155026.1 hypothetical protein -
  GWK37_RS14965 (GWK37_14975) spxH 3008637..3009539 (-) 903 WP_115940904.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=419258 GWK37_RS14950 WP_003155032.1 3004121..3004777(+) (mecA) [Bacillus velezensis strain CACC 316]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=419258 GWK37_RS14950 WP_003155032.1 3004121..3004777(+) (mecA) [Bacillus velezensis strain CACC 316]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAAGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment